1. About Vostar-R
Vostar-R is a medicine that reduces inflammation and pain.
It's used to treat aches and pains, as well as problems with joints, muscles and bones. These include:
Vostar-R comes as tablets, capsules and suppositories. These are available on prescription only.
It can also be given as an injection or as eyedrops. These are usually only given in hospital.
Vostar-R gel and plasters for joint pain are available to buy from pharmacies.
What Are Side Effects Associated with Using Vostar-R?
Side effects associated with use of Vostar-R, include the following:
This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.
Mechanism Of Action
Vostar-R has analgesic, anti-inflammatory, and antipyretic properties.
The mechanism of action of VOLTAREN, like that of other NSAIDs, is not completely understood but involves inhibition of cyclooxygenase (COX-1 and COX-2).
Vostar-R is a potent inhibitor of prostaglandin synthesis in vitro. Vostar-R concentrations reached during therapy have produced in vivo effects. Prostaglandins sensitize afferent nerves and potentiate the action of bradykinin in inducing pain in animal models. Prostaglandins are mediators of inflammation. Because Vostar-R is an inhibitor of prostaglandin synthesis, its mode of action may be due to a decrease of prostaglandins in peripheral tissues.
Vostar-R interactions and warnings
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking your Vostar-R dosage, it is important that your doctor knows:
- If you have asthma or any other allergic disorder.
- If you have ever had a stomach or duodenal ulcer, or if you have an inflammatory bowel disorder such as Crohn's disease or ulcerative colitis.
- If you have a heart condition, or a problem with your blood vessels or circulation.
- If you are pregnant or breastfeeding.
- If you have high blood pressure.
- If you have any blood clotting problems.
- If you have a connective tissue disorder, such as a condition called systemic lupus erythematosus (SLE).
- If you have problems with the way your liver works, or problems with the way your k >
Vostar-R interacts with many different drugs. It’s always important to tell your doctor and pharmacist about all of the treatments you are taking.
This includes not only all of your prescription and over-the-counter medicines, but also products that may not seem like medication, such as: vitamins and other dietary supplements (nutritional shakes, protein powders, etc.), and herbals along with any legal or illegal recreational drugs.
You should not take Vostar-R if you are taking the following drugs:
- Apixaban (Eliquis)
- Elvitegravir/cobicistat/emtricitabine/tenofovir (Stirbild)
- Ketorolac nasal spray (Sprix)
- Methotrexate (Trexall)
- Premetrexed (Alimta)
- Pirfinidone (Esbriet)
If you are taking any of the following, talk to your doctor about drug options other than Vostar-R:
- Blood thinners, such as fondaparinux (Arixtra), dabigatran (Pradaxa) warfarin (Jantoven, Coumadin) or heparin
- Antidepressants, such as citalopram (Celexa), paroxetine (Paxil), or escitalopram (Lexapro)
- Water pills, such as hydrochlorothiazide (Esidrix, Microzide), chorthalidone (Thalitone), or chlorothiazide (Diuril)
- Beta blockers, such as acebutolol (Sectral), bisoprolol ( Zebeta), atenolol (Tenormin), esmolol (Brevibloc), or carvedilol (Coreg)
- Other NSAIDS, including: celecoxib (Celebrex), naproxen (Aleve, Naprosyn), meloxicam (Mobic), nabumetone (Relafen), or etodolac (Lodine)
- Diabetes medications called sulfonylureas, such as glimepiride (Amaryl), glyburide (DiaBeta, Micronase, Glynase), and glipizide (Glucotrol)
COMMON BRAND(S): Voltaren
GENERIC NAME(S): Vostar-R Sodium
Nonsteroidal anti-inflammatory drugs (including Vostar-R) may rarely increase the risk for a heart attack or stroke. This effect can happen at any time while taking this drug but is more likely if you take it for a long time. The risk may be greater if you have heart disease or increased risk for heart disease (for example, due to smoking, family history of heart disease, or conditions such as high blood pressure or diabetes). Do not take this drug right before or after heart bypass surgery (CABG).
Also, this drug may rarely cause serious (rarely fatal) bleeding from the stomach or intestines. This effect can occur without warning symptoms at any time while taking this drug. Older adults may be at higher risk for this effect. (See also Precautions and Drug Interactions sections.)
Stop taking Vostar-R and get medical help right away if you notice any of the following rare but serious side effects: bloody or black/tarry stools, persistent stomach/abdominal pain, vomit that looks like coffee grounds, chest/jaw/left arm pain, shortness of breath, unusual sweating, weakness on one side of the body, sudden vision changes, slurred speech.
Talk with your doctor or pharmacist about the risks and benefits of treatment with this medication.
Vostar-R is used to relieve pain, swelling (inflammation), and joint stiffness caused by arthritis. Reducing these symptoms helps you do more of your normal daily activities. This medication is known as a nonsteroidal anti-inflammatory drug (NSAID).
If you are treating a chronic condition such as arthritis, ask your doctor about non-drug treatments and/or using other medications to treat your pain. See also Warning section.
Vostar-R and Alcohol
You should not drink alcohol while taking Vostar-R. It can increase the risk of stomach bleeding and may cause damage to your kidneys.