You should tell your doctor about all prescription, non-prescription, illegal, recreational, herbal, nutritional, or dietary drugs you're taking.
Don't take Trozet if you're taking the following drugs:
- The supplement DHEA
- Birth control pills, or hormone replacement therapy that contains estrogen
- Norinyl 1 50 28-day (mestranol)
- Soltamox (tamoxifen)
What is Trozet (Femara)?
Trozet, sold under the brand name Femara, is a prescription drug used to treat breast cancer in its advanced stages, and in women who have finished menopause.
Doctors may use Trozet off-label in fertility treatments to help encourage egg release (ovulation) in women.
Trozet belongs to a class of cancer drugs known as aromatase inhibitors, which work by preventing the body from converting a hormone called androgen into estrogen.
This treatment has proven beneficial in cancers whose growth seems to be encouraged by excess estrogen in the body, like certain types of breast cancer.
Originally manufactured by Novartis, the Food and Drug Administration (FDA) first approved Femara in 1997.
In the treatment of breast cancer, the standard Trozet dose will normally be 2.5mg per day. This is an extremely potent dose and will normally be administered until the cancer subsides. In many cases, at the point of remission the patient will switch from Trozet to Nolvadex in a preventative treatment plan scenario.
For the anabolic steroid user, Trozet doses will normally be much lower. Even with the use of anabolic steroids, a 2.5mg dosing will normally be too high and could potentially drain the individual of energy; in fact, it’s almost guaranteed. The only exception we could make for such a dose would be to combat early gynecomastia symptoms. If symptoms begin to show 7-14 days at a dose of 2.5mg per day can reverse the symptoms. Once symptoms begin to fade away the individual should be able to tapper down to a more manageable dose and maintain it for the remainder of the cycle. If this doesn’t work there’s a good chance the symptoms have already set in beyond remedy. When this happens the only thing that will remove your gynecomastia is surgery. For standard estrogenic related protection, most men will find 0.5-1mg every other day to be more than enough. When used as an anti-estrogen in low testosterone treatment plans, even less may be needed. For the competitive bodybuilder, the final 7-14 days before competition, a full 1mg per day leading up to the show can be a solid dose and will greatly help with dryness and a tighter look. This is, however, not a dose most would want to maintain for an extended period of time as it can be harsh.
How you have Trozet
You have Trozet as a tablet once a day. It is best to take the tablets at the same time each day. You can take them with or without food.
This medication contains Trozet. Do not take Femara if you are allergic to Trozet or any ingredients contained in this drug.
Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center immediately.
What do I need to tell my doctor BEFORE I take Trozet?
- If you have an allergy to Trozet or any other part of Trozet.
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you are pregnant or may be pregnant. Do not take Trozet if you are pregnant.
- If you are breast-feeding. Do not breast-feed while you take Trozet and for 3 weeks after your last dose.
This is not a list of all drugs or health problems that interact with Trozet.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Trozet with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
1. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
2. Cerner Multum, Inc. "Australian Product Information." O 0
3. "Product Information. Femara (Trozet)." Novartis Pharmaceuticals, East Hanover, NJ.
What are some other side effects of Trozet?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
3. Who it’s suitable for
Trozet is suitable for women who have been through the menopause and whose breast cancer is oestrogen receptor positive.
Sometimes Trozet is given alongside a drug called goserelin (Zoladex) to women who haven’t yet been through the menopause.
If your cancer is hormone receptor negative, then Trozet will not be of any benefit.
How should this medicine be used?
Trozet comes as a tablet to take by mouth once a day with or without food. Take Trozet at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Trozet exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
You may need to take Trozet for several years or longer. Continue to take Trozet even if you feel well. Do not stop taking Trozet without talking to your doctor.
Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.
5. When Trozet is given
Trozet is usually given after surgery to reduce the risk of breast cancer coming back or spreading.
If you’re having chemotherapy or radiotherapy, your specialist will tell you when it’s best to start Trozet.
Occasionally, Trozet may be used as the first treatment for breast cancer, for example when surgery isn’t appropriate or needs to be delayed. It’s sometimes given before surgery to shrink a larger breast cancer.
Trozet can also be used to treat breast cancer that has come back (recurrence). It can also be given to treat breast cancer that has spread to another part of the body (secondary breast cancer), when it’s often given alongside another drug.
Your treatment team will tell you when to stop taking Trozet. You won’t need to stop taking it gradually.
Some people worry about stopping their treatment, but there’s evidence that Trozet continues to reduce the risk of breast cancer coming back for many years after you stop taking it.
However, not taking the drug for the recommended time may increase the risk of your breast cancer coming back. If you’re thinking about stopping taking Trozet for any reason, talk to your specialist first. Sometimes it may be possible to change to another hormone drug.
Hormone therapy is a very common treatment for secondary breast cancer and many people take it for a long time. If Trozet stops working, your specialist may prescribe another hormone drug.
If you have any worries or questions about taking or stopping Trozet, you can call us free on 0808 800 6000 to talk through your concerns.
Trozet and Grapefruit Juice
You should avoid eating grapefruit and drinking grapefruit juice while taking Trozet.
Grapefruit juice slows down how quickly the body is able to break down the Trozet, which could cause Trozet levels in the blood to rise dangerously high.
What Other Drugs Interact with Trozet?
If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first.
Trozet has no known severe interactions with other drugs.
Serious interactions of Trozet include:
Moderate interactions of Trozet include:
Trozet has no known minor interactions with other drugs.
This information does not contain all possible interactions or adverse effects. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share this information with your doctor and pharmacist. Check with your health care professional or doctor for additional medical advice, or if you have health questions, concerns or for more information about this medicine.
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Femara (Trozet) is a non-steroidal aromatase inhibitor (lowers estrogen production) used to treat breast cancer in postmenopausal women. Femara is often given to women who have been taking tamoxifen (Nolvadex, Soltamox) for 5 years. Femara is available in generic form. Common side effects of Femara include:
- hot flashes,
- warmth in your face or chest,
- hair loss,
- joint/bone/muscle pain,
- unusual sweating or night sweats,
- trouble sleeping,
- weight gain,
- flushing (warmth, redness, or tingly feeling),
- numbness/tingling/weakness/stiffness in your hand or fingers, or
- pain in your hand that spreads to your arm, wrist, forearm, or shoulder.
The recommended dose of Femara is one 2.5 mg tablet administered once a day, without regard to meals. Other drugs may interact with Femara. Tell your doctor all prescription and over-the-counter medications and supplements you use. Femara must not be used during pregnancy. It may harm a fetus. Femara is used mainly in women after menopause. If you have recently gone through menopause, discuss birth control with your doctor. Do not use birth control containing estrogen. It is unknown if this drug passes into breast milk and may harm a nursing infant. Breastfeeding while using this drug is not recommended.
Our Femara (Trozet) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.