Ruvominox tablets

Ruvominox

  • Active Ingredient: Diclofenac
  • 100 mg
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What is Ruvominox?

The active ingredient of Ruvominox brand is diclofenac. Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID). This medicine works by reducing substances in the body that cause pain and inflammation. The inactive ingredients in Diclofenac sodium delayed-release tablets include: hydroxypropyl methylcellulose, lactose monohydrate, magnesium stearate, methacrylic acid copolymer, microcrystalline cellulose, polyethylene glycol, povidone, propylene glycol, sodium starch glycolate, talc, titanium dioxide, triethyl citrate.

Used for

Ruvominox is used to treat diseases such as: Ankylosing Spondylitis, Aseptic Necrosis, Back Pain, Frozen Shoulder, Migraine, Muscle Pain, Osteoarthritis, Pain, Period Pain, Rheumatoid Arthritis, Sciatica, Spondyloarthritis.

Side Effect

Possible side effects of Ruvominox include: severe stomach pain; Agitation; diarrhea; irregular, fast or slow, or shallow breathing; muscle twitching; passing gas; excess air or gas in the stomach or intestines; weight loss.

How to Buy Ruvominox gel online?

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Pregnancy and Ruvominox

Because risk of damage to the unborn child varies during pregnancy, Ruvominox falls under two FDA pregnancy categories:

  • In the first 29 weeks of pregnancy, Ruvominox has a category C rating: There is a risk of harm to the fetus, but it has not yet been confirmed in humans.
  • During or after the 30th week of pregnancy, Ruvominox has a category D rating: In this case, the drug can cause a birth defect by causing a major artery to close that nourishes the baby’s heart. So you should only take Ruvominox if there are no other safer options available.

Regardless, you should tell your doctor if you are pregnant or plan to become pregnant before taking this medication.

You should also alert your physician if you are breastfeeding or plan to breastfeed. Ruvominox is found in breast milk, and mothers should avoid taking this drug while nursing.

INDICATIONS

Carefully consider the potential benefits and risks of VOLTAREN ® (Ruvominox sodium enteric-coated tablets) and other treatment options before deciding to use VOLTAREN. Use the lowest effective dose for the shortest duration consistent with individual patient treatment goals (see WARNINGS; Gastrointestinal Bleeding, Ulceration, And Perforation).

VOLTAREN is indicated:

  • For relief of the signs and symptoms of osteoarthritis
  • For relief of the signs and symptoms of rheumatoid arthritis
  • For acute or long-term use in the relief of signs and symptoms of ankylosing spondylitis

Ruvominox sodium administered to male and female rats at 4 mg/kg/day (approximately 0.2 times the MRHD based on BSA comparison) did not affect fertility.

Based on the mechanism of action, the use of prostaglandin-mediated NSAIDs, including VOLTAREN, may delay or prevent rupture of ovarian follicles, which has been associated with reversible infertility in some women. Published animal studies have shown that administration of prostaglandin synthesis inhibitors has the potential to disrupt prostaglandin-mediated follicular rupture required for ovulation. Small studies in women treated with NSAIDs have also shown a reversible delay in ovulation. Consider withdrawal of NSAIDs, including VOLTAREN, in women who have difficulties conceiving or who are undergoing investigation of infertility.

General

VOLTAREN ® (Ruvominox sodium enteric-coated tablets) cannot be expected to substitute for corticosteroids or to treat corticosteroid insufficiency. Abrupt discontinuation of corticosteroids may lead to disease exacerbation. Patients on prolonged corticosteroid therapy should have their therapy tapered slowly if a decision is made to discontinue corticosteroids and the patient should be observed closely for any evidence of adverse effects, including adrenal insufficiency and exacerbation of symptoms of arthritis. The pharmacological activity of VOLTAREN in reducing fever and inflammation may diminish the utility of these diagnostic signs in detecting complications of presumed noninfectious, painful conditions.

Histopathology

Ruvominox hepatotoxicity is typically associated with an acute hepatitis-like histology with necrosis that may be most prominent in zone 3 (centrally). There is usually focal necrosis and inflammation, but with severe cases the injury can be confluent or submassive. Chronic hepatitis-like injury with prominence of portal inflammation, interface hepatitis and fibrosis can be found, particularly in cases with longer latency and more prolonged course. A minority of cases showed mixed hepatocellular cholestatic injury (cholestatic hepatitis) with varying degrees of inflammation. Three photomicrographs are shown.

Ruvominox and Grapefruit Juice

Whether grapefruit interacts with Ruvominox remains uncertain. Therefore, your best bet is to avoid all grapefruit products while taking Ruvominox.

How it works

Ruvominox is a nonsteroidal anti-inflammatory drug (NSAID).

The drug works by blocking a particular enzyme in your body. When the enzyme is blocked, your body decreases the amount of inflammatory chemicals it makes. This helps to reduce inflammation and pain.

Ruvominox topical gel may cause drowsiness. Don’t drive or use machinery until you know how this drug affects you.

Ruvominox can also cause other side effects.

Warnings for other groups

For pregnant women: Before 30 weeks of pregnancy, this drug is a pregnancy category C drug. After 30 weeks of pregnancy, it’s a pregnancy category D drug.

A category C drug means that means that studies have shown that the drug can be a risk to the offspring of lab animals. However, not enough studies have been done to show risk in humans.

Category D means two things:

  1. Studies show a risk of adverse effects to the fetus when the mother uses the drug.
  2. The benefits of using Ruvominox during pregnancy may outweigh the potential risks in certain cases.

Do not use Ruvominox if you’re pregnant, unless your doctor advises you to. Be especially sure to avoid using Ruvominox at 30 weeks of pregnancy and later.

For women who are breastfeeding: This drug may pass into the breast milk, which means it may pass to a child who is breastfed. This may lead to dangerous effects for the child.

Talk to your doctor regarding whether breastfeeding is a good choice for you.

For seniors: Seniors are at higher risk for stomach problems, bleeding, water retention, and other side effects from Ruvominox. Seniors may also have kidneys that aren’t working at peak levels, so the drug can build up and cause more side effects.

What is the dosage for Ruvominox?

Ruvominox should be taken with food to reduce stomach upset. The recommended dose for most conditions is 100-200 mg daily. Dosing intervals are 2 to 4 times daily depending on the Ruvominox formulation used and the condition being treated.


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