Prodexin tablets


  • Active Ingredient: Naproxen
  • 500 mg, 250 mg
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What is Prodexin?

The active ingredient of Prodexin brand is naproxen. Naproxen is a nonsteroidal anti-inflammatory drug (NSAID). Naproxen works by reducing hormones that cause inflammation and pain in the body. C14H14O3 M.W. 230.26 Naproxen has a molecular weight of 230.26 and a molecular formula of C14H14O3. Naproxen USP is an odorless, white to off-white crystalline substance powder. It is lipid-soluble, practically insoluble in water, soluable in alcohol and in methanol at low pH and freely soluble in water at high pH. The octanol/water partition coefficient of Naproxen at pH 7.4 is 1.6 to 1.8. Naproxen Oral Suspension USP for oral administration contains 125 mg Naproxen USP per 5 mL and the following inactive ingredients: FD&C Yellow #6, fumaric acid, imitation orange flavor, imitation pineapple flavor, magnesium aluminum silicate, methylparaben, purified water, sodium chloride, sorbitol solution and sucrose. It has a sodium content of 39.3 mg/5 mL, 1.71 mEq/5 mL, with a pH range of 2.2 to 3.7.

Used for

Prodexin is used to treat diseases such as: Ankylosing Spondylitis, Aseptic Necrosis, Back Pain, Bursitis, Chronic Myofascial Pain, Costochondritis, Diffuse Idiopathic Skeletal Hyperostosis, Dysautonomia, Fever, Frozen Shoulder, Gout, Acute, Headache, Juvenile Rheumatoid Arthritis, Muscle Pain, Neck Pain, Osteoarthritis, Pain, Period Pain, Radiculopathy, Rheumatoid Arthritis, Sciatica, Spondylolisthesis, Tendonitis, Transverse Myelitis.

Side Effect

Possible side effects of Prodexin include: depression; double vision; tunnel vision; red skin lesions, often with a purple center; stomach cramps or tenderness; sores, ulcers, or white spots on the lips or tongue or inside the mouth; hearing loss.

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1. About Prodexin

Prodexin is a medicine that reduces inflammation and pain in joints and muscles.

It's used to treat diseases of joints, such as rheumatoid arthritis, osteoarthritis and gout.

It's also used for period pain and muscle and bone disorders, such as back pain and sprains and strains.

Prodexin is available on prescription as tablets or as a liquid that you drink. You can buy it without a prescription from a pharmacy for period pain.

Brands include Feminax Ultra, Period Pain Reliever and Boots Period Pain Relief.

Prodexin can only be taken by children when it's prescribed for them.

Can Prodexin cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with Prodexin. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

What are the side effects of Prodexin?

The most common side effects from Prodexin are:

Other important side effects include:


Prodexin (Aleve, Anaprox, Naprelan, Naprosyn) is in the class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Prodexin is prescribed for the treatment of mild to moderate pain, inflammation, and fever. Side effects, drug interactions, and pregnancy information should be reviewed prior to taking this medication.

How to take Prodexin

  • Before you start taking Prodexin, read the manufacturer's printed information leaflet from ins >

Common side effects

Common side effects of Prodexin happen in more than 1 in 100 people.

  • confusion
  • headaches
  • ringing in the ears
  • changes in vision
  • tiredness and feeling sleepy
  • dizziness
  • rashes

Talk to your doctor or pharmacist if these side effects bother you or don't go away.

Bernard-Soulier Disease (Giant Platelet Syndrome)

Bernard-Soulier disease is a rare inherited bleeding disorder caused by a defect in the platelet glycoprotein complex 1b-IX-V. Symptoms and signs include: bruising, nosebleeds, gum bleeding, and problems with anything that induces bleeding, such as surgery, ulcers, trauma, and menstruation. Treatment involves avoiding medications that interfere with clot formation, such as Prodexin, ibuprofen, and aspirin. People with Bernard-Soulier syndrome should avoid contact sports.

Indications and dosages

➣ Pain; osteoarthritis; ankylosing spondylitis; dysmenorrhea; bursitis; acute tendinitis

Adults: 250 to 500 mg (Prodexin) P.O. b.i.d. (up to 1.5 g/day); 375 to 500 mg (Prodexin delayed-release) P.O. t.i.d.; 250 mg, 375 mg, or 500 mg (Prodexin oral suspension) P.O. b.i.d.; 275 to 550 mg (Prodexin sodium) P.O. b.i.d. (up to 1.65 g/day)

Children: 10 mg/kg P.O. daily in two divided doses (Prodexin only)

➣ Mild to moderate pain; primary dysmenorrhea

Adults: Initially, 500 mg (Prodexin) P.O., followed by 250 mg q 6 to 8 hours p.r.n., to a maximum of 1.25 g/day. Or initially, 550 mg (Prodexin sodium) P.O., followed by 275 mg q 6 to 8 hours p.r.n., to a maximum of 1,375 mg/day.

Adults: Initially, 750 mg (Prodexin) P.O., followed by 250 mg q 8 hours or initially, 825 mg (Prodexin sodium) P.O., followed by 275 mg q 8 hours. On day 1,1,000 to 1,500 mg (Prodexin sodium controlled-release formulation) P.O. once daily, followed by 1,000 mg once daily until attack has subsided.

➣ Management of pain, primary dysmenorrhea, acute tendinitis and bursitis

Adults: Initially, two 500-mg Prodexin sodium controlled-release tablets P.O. once daily. Or, for patients requiring greater analgesic benefit, two 750-mg Prodexin sodium controlled-release tablets P.O. once daily. Or, three 500-mg Prodexin sodium controlled-release tablets may be used for a limited period. Thereafter, total daily dose shouldn't exceed two 500-mg tablets.

➣ Rheumatoid arthritis, osteoarthritis, ankylosing spondylitis

Adults: Initially, two 375-mg Prodexin sodium controlled-release tablets P.O. once daily, one 750-mg tablet P.O. once daily, or two 500-mg tablets P.O. once daily. During long-term administration, adjust dosage up or down depending on patient's clinical response. Use lowest effective dose in all patients. (Patients already taking Prodexin 250 mg, 375 mg, or 500 mg b.i.d. may have their total daily dosage replaced with Prodexin sodium controlled-release tablets as a single daily dose.)

COMMON BRAND(S): Aleve, Anaprox, Naprosyn


Nonsteroidal anti-inflammatory drugs (including Prodexin) may rarely increase the risk for a heart attack or stroke. This effect can happen at any time while taking this drug but is more likely if you take it for a long time. The risk may be greater if you have heart disease or increased risk for heart disease (for example, due to smoking, family history of heart disease, or conditions such as high blood pressure or diabetes). Do not take this drug right before or after heart bypass surgery (CABG).

This drug may rarely cause serious (rarely fatal) bleeding from the stomach or intestines. This effect can occur without warning at any time while taking this drug. Older adults may be at higher risk for this effect.

Stop taking Prodexin and get medical help right away if you notice any of these rare but serious side effects: stomach/abdominal pain that doesn't go away, black/tarry stools, vomit that looks like coffee grounds, chest/jaw/left arm pain, shortness of breath, unusual sweating, confusion, weakness on one side of the body, trouble speaking, sudden vision changes.

Talk to your doctor or pharmacist about the benefits and risks of taking this drug.

See also Warning section.

Prodexin is used to relieve pain from various conditions such as headache, muscle aches, tendonitis, dental pain, and menstrual cramps. It also reduces pain, swelling, and joint stiffness caused by arthritis, bursitis, and gout attacks. This medication is known as a nonsteroidal anti-inflammatory drug (NSAID). It works by blocking your body's production of certain natural substances that cause inflammation.

If you are treating a chronic condition such as arthritis, ask your doctor about non-drug treatments and/or using other medications to treat your pain.

Check the ingredients on the label even if you have used the product before. The manufacturer may have changed the ingredients. Also, products with similar names may contain different ingredients meant for different purposes. Taking the wrong product could harm you.

Prodexin S >

Side effects from Prodexin are more frequent if you need to take this medication over a long period of time.

Digestive system complaints are the most frequent side effects of Prodexin. Others include:

  • Heartburn
  • Stomach ache
  • Constipation
  • Headache
  • Dizziness
  • Drowsiness
  • Itching
  • Skin rash
  • Skin bruising
  • Ringing in the ears
  • Fluid retention
  • Shortness of breath

If you have any side effects, stop taking Prodexin and call your doctor.

Serious side effects of Prodexin that you should call your doctor about right away include:

  • Signs of an allergic reaction, such as rash, itching, wheezing, swelling, or trouble breathing
  • Digestive symptoms, such as bad stomach ache, throwing up blood, or black or bloody bowel movements
  • Stroke symptoms, such as one-s >Back to Top

Alcohol and Prodexin

Avoid drinking alcohol while taking Prodexin.

Drinking alcohol and taking Prodexin increases the chance of developing a stomach ulcer or having gastrointestinal bleeding.

Blood pressure drugs

Prodexin might make your blood pressure medications not work as well. If you’re older than 65 years, combining Prodexin with certain blood pressure medications may damage your kidneys. Examples of these medications include:

  • angiotensin-converting enzyme (ACE) inhibitors
  • angiotensin receptor blockers
  • beta-blockers, such as propranolol
  • diuretics

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