Prekursan tablets

Prekursan

  • Active Ingredient: Diclofenac
  • 100 mg
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What is Prekursan?

The active ingredient of Prekursan brand is diclofenac. Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID). This medicine works by reducing substances in the body that cause pain and inflammation. The inactive ingredients in Diclofenac sodium delayed-release tablets include: hydroxypropyl methylcellulose, lactose monohydrate, magnesium stearate, methacrylic acid copolymer, microcrystalline cellulose, polyethylene glycol, povidone, propylene glycol, sodium starch glycolate, talc, titanium dioxide, triethyl citrate.

Used for

Prekursan is used to treat diseases such as: Ankylosing Spondylitis, Aseptic Necrosis, Back Pain, Frozen Shoulder, Migraine, Muscle Pain, Osteoarthritis, Pain, Period Pain, Rheumatoid Arthritis, Sciatica, Spondyloarthritis.

Side Effect

Possible side effects of Prekursan include: hives; dizziness; Abdominal or stomach bloating, burning, cramping, or pain; muscle twitching; diarrhea.

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The apparent volume of distribution (V/F) of Prekursan sodium is 1.4 L/kg.

Prekursan is more than 99% bound to human serum proteins, primarily to albumin. Serum protein binding is constant over the concentration range (0.15-105 mcg/mL) achieved with recommended doses.

Prekursan diffuses into and out of the synovial fluid. Diffusion into the joint occurs when plasma levels are higher than those in the synovial fluid, after which the process reverses and synovial fluid levels are higher than plasma levels. It is not known whether diffusion into the joint plays a role in the effectiveness of Prekursan.

Q: Could Prekursan cause excess bleeding from dental surgery?

A: Prekursan (Cataflam, Flector, Voltaren-XR, Zipsor) can affect platelets and may prolong bleeding. As always, consult with your health care provider regarding what medications need to be stopped prior to dental surgery. Jennyfer Marisco, RPh

Why is this medication prescribed?

Prekursan capsules (Zipsor, Zorvolex) and tablets (Cataflam) are used to relieve mild to moderate pain. Prekursan extended-release tablets (Voltaren XR), tablets (Cataflam), and delayed release tablets (available generically) are used to relieve pain, tenderness, swelling, and stiffness caused by osteoarthritis (arthritis caused by a breakdown of the lining of the joints), and rheumatoid arthritis (arthritis caused by swelling of the lining of the joints). Prekursan extended-release tablets and delayed-release tablets are also used to treat ankylosing spondylitis (arthritis that mainly affects the spine). Prekursan tablets (Cataflam) are also used to treat painful menstrual periods. Prekursan solution (Cambia) is used to treat migraine headaches in adults, but cannot be used to prevent migraines or to treat other types of headaches. Prekursan is in a class of medications called NSAIDs. It works by stopping the body's production of a substance that causes pain, fever, and inflammation.

Other warnings

  • High blood pressure warning: This drug can cause high blood pressure, or worsen high blood pressure if you already have it. Your doctor will likely monitor your blood pressure while you use this drug.
  • Water retention warning: This drug can cause your body to retain water, leading to edema (swelling or puffiness).
  • Liver function warning: Using Prekursan may affect some of your liver function tests. Your doctor should monitor your liver function while you use Prekursan.
  • Allergic reaction warning: If you have an allergy to aspirin or other nonstero >

Prekursan is a prescription drug. It comes as a topical gel, oral capsule, oral tablet, eye drops, transdermal patch, topical solution, and powder packets for oral solution.

Prekursan topical gel is available as the brand-name drugs Solaraze and Voltaren. It’s also available as a generic drug. Generic drugs usually cost less than brand-name versions. In some cases, they may not be available in every strength or form as a brand-name drug.

Why it’s used

Prekursan topical gel is used to help relieve osteoarthritis pain in joints that can benefit from treatment through the skin. These joints include those in your hands and knees.

Prekursan topical gel is also used to treat actinic keratosis (AK). This condition causes rough, scaly spots on the skin of older adults.

Rated Prekursan for Moderate Pain Report

Cause swelling itching hives breathing problems severe upset stomach throwing up dizziness diarrhea I had to take Benadryl I thought I was going to have to go to the ER never never again this drug for me the interactions or not good

Mixing Prekursan with herbal remedies or supplements

It's not possible to say that complementary medicines or herbal remedies are safe to take with Prekursan.

They're not tested in the same way as prescription medicines or medicines sold in pharmacies. They're generally not tested for the effect they can have on other medicines.

4. How and when to use them

You'll usually take Prekursan tablets, capsules or suppositories 2 to 3 times a day.

The standard dose is 75mg to 150mg a day, depending on what your doctor prescribes for you. Follow your doctor's advice on how many tablets to take, and how many times a day.

If your doctor prescribes Prekursan for your child, they'll use your child's weight to work out the right dose for them.

If you have pain all the time, your doctor may recommend slow-release Prekursan tablets or capsules. It's usual to take these either once a day in the evening, or twice a day.

If you're taking slow-release Prekursan twice a day, leave a gap of 10 to 12 hours between your doses.

Rated Prekursan for Myalgia Report

The Oral Prekursan was horrendous on my stomach from the first pill. Didn't help with all over connective tissue pain. Stopped taking it after 2 pills. That Said: the Topical Prekursan gel works miracles on almost All types of pain including arthritis to muscle and even headaches. I rub this gel (light cream) into all parts of body and the pain is either reduced or completely gone. Don't be concerned about the amount of topical gel you rub into the body as only a tiny (less than 4 percent) of the active ingredient makes it into the body causing issues. No issues at all with the topical and many doctors and patients view this gel as a real pain reducer. I have literally rubbed this gel onto arms, legs, back, neck and forehead and horrendous pain reduced hugely. With the war on opioids being waged against chronic pain patients this is one fantastic pain reducing weapon. Slather this on, rub it in, but do Not take the oral version of Prekursan.

Introduction

Prekursan is a commonly used nonsteroidal antiinflammatory drug (NSAID) used for the therapy of chronic forms of arthritis and mild-to-moderate acute pain. Therapy with Prekursan in full doses is frequently associated with mild serum aminotransferase elevations and, in rare instances, can lead to serious clinically apparent, acute or chronic liver disease.

Rated Prekursan for Pain Report

I have had chronic pain in numerous parts of my body. My doctor prescribed this for very bad pain. So far I've been taking it twice a day@ 75 Mg for a bit over a week now. And all it's done for me is upset my stomach and give me NO relief from the pain.

What is Prekursan, and how does it work (mechanism of action)?

Prekursan belongs to a class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs) that are used for the treatment of mild to moderate pain, fever, and inflammation. Other members of this class include ibuprofen (Motrin), indomethacin (Indocin), nabumetone (Relafen), naproxen (Aleve) and several others. NSAIDs work by reducing the production of prostaglandins, chemicals that cause pain, fever and inflammation. NSAIDs block the enzyme that makes prostaglandins (cyclooxygenase), resulting in lower production of prostaglandins. As a consequence, inflammation, pain and fever are reduced. Since the response to different NSAIDs varies from patient to patient, it is not unusual for a doctor to try different NSAIDs for any given condition. The FDA approved Prekursan in July 1998.

Other NSAIDs

Prekursan is a nonsteroidal anti-inflammatory drug (NSAID). Don’t combine it with other NSAIDs unless directed by your doctor, as this may increase your risk of stomach and bleeding issues. Examples of other NSAIDs include:

Prekursan sodium did not show mutagenic activity in in vitro point mutation assays in mammalian (mouse lymphoma) and microbial (yeast, Ames) test systems and was nonmutagenic in several mammalian in vitro and in vivo tests, including dominant lethal and male germinal epithelial chromosomal studies in mice, and nucleus anomaly and chromosomal aberration studies in Chinese hamsters.


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