Taking digoxin with Pinanac can lead to increased levels of digoxin in your body and increased side effects. Your doctor may monitor your digoxin levels closely.
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.
This drug comes with several warnings.
Q: What are the side effects of Pinanac?
A: Pinanac is a medication in the NSAID family of drugs that is used to treat pain caused by inflammation. Pinanac is used to treat a variety of conditions including arthritis, migraines, and joint pain. The prescribing information on Pinanac lists the following as the most common side effects of the medication: stomach pain constipation or diarrhea heartburn gas nausea/vomiting dizziness swelling ringing of the ears. Some side effects that you should report to your physician include: slurred speech confusion weakness shortness of breath high blood pressure dark, tarry stools dark urine yellowing of the skin or eyes rapid weight gain or unusual swelling of the hands, feet or ankles. Lori Poulin, PharmD
Pinanac vs Ibuprofen drug interactions
Pinanac may have serious interaction with following drugs:
· aspirin/citric acid/sodium bicarbonate
Ibuprofen may have serious interaction with following drugs:
Q: What kind of over the counter pain relievers can I take with Pinanac?
A: Pinanac belongs to the class of drugs known as nonsteroidal anti-inflammatory drugs or NSAIDs. The use of Pinanac with over-the-counter pain relievers would generally be limited to acetaminophen (Tylenol and others). All other over-the-counter pain relievers contain aspirin or other NSAIDs, such as ibuprofen and naproxen. The use of multiple NSAIDs is not generally recommended because of the potential for increased side effects, such as gastrointestinal upset and bleeding. Michelle McDermott, PharmD
Q: Arthrotrec is known for weight gain due to fluid retention and renal difficulties. Should I consult a doctor for a diuretic to lose excess fluid weight?
A: Arthrotec is a combination of Pinanac and misoprostol. Pinanac belongs to the group of drugs known as nonsteroidal anti-inflammatory drug (NSAIDs) and has analgesic and anti-inflammatory effects. Misoprostol is a gastrointestinal protective agent that is used in combination with NSAIDs to reduce the risk of stomach or intestinal ulcers. Arthrotec is used for the treatment of the signs and symptoms of osteoarthritis or rheumatoid arthritis in patients who are at high risk of developing a stomach or intestinal ulcer with NSAID therapy. Patients who have had a stomach ulcer or gastrointestinal bleeding are at 10 times greater risk of having gastrointestinal bleeding when taking a NSAID. Other factors that increase the risk of gastrointestinal bleeding in patients taking NSAIDs include use of oral corticosteroids or blood thinners, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. The most common side effects of Arthrotec are abdominal pain, diarrhea, upset stomach, nausea, and gas. Arthrotec, like other NSAIDs, can cause heart, kidney, and/or liver problems. Patients should be aware of the signs and symptoms of these possible conditions, including chest pain, shortness of breath, weakness, slurring of speech, swelling, unexplained weight gain, nausea, fatigue, itching, yellowing of the skin or eyes, or right upper quadrant tenderness. If you develop these signs or symptoms, please consult with your health care provider for guidance based on your health status and current medications, particularly before taking any action. Michelle McDermott, PharmD
By Frieda Wiley, PharmD, CGP, RPh | Medically Reviewed by Robert Jasmer, MD
Latest Update: 2015-01-14 Copyright © 2014 Everyday Health Media, LLC
Blood pressure drugs
Pinanac may decrease the blood pressure-lowering effects of some drugs used to control blood pressure. Using Pinanac with certain blood pressure medications may also increase your risk of kidney damage.
Examples of these blood pressure drugs include:
- angiotensin-converting enzyme (ACE) inhibitors, such as benazepril, captopril, enalapril, and lisinopril
- angiotensin II receptor blockers, such as candesartan, irbesartan, losartan, and olmesartan
- beta blockers, such as acebutolol, atenolol, metoprolol, and propranolol
- diuretics (water pills) such as furosemide or hydrochlorothiazide
Using the cancer drug pemetrexed with Pinanac may increase the effects of pemetrexed. Symptoms may include fever, chills, body aches, mouth sores, and severe diarrhea.
Pinanac and Alcohol
You should not drink alcohol while taking Pinanac. It can increase the risk of stomach bleeding and may cause damage to your kidneys.