Nycopren tablets

Nycopren

  • Active Ingredient: Naproxen
  • 500 mg, 250 mg
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What is Nycopren?

The active ingredient of Nycopren brand is naproxen. Naproxen is a nonsteroidal anti-inflammatory drug (NSAID). Naproxen works by reducing hormones that cause inflammation and pain in the body. C14H14O3 M.W. 230.26 Naproxen has a molecular weight of 230.26 and a molecular formula of C14H14O3. Naproxen USP is an odorless, white to off-white crystalline substance powder. It is lipid-soluble, practically insoluble in water, soluable in alcohol and in methanol at low pH and freely soluble in water at high pH. The octanol/water partition coefficient of Naproxen at pH 7.4 is 1.6 to 1.8. Naproxen Oral Suspension USP for oral administration contains 125 mg Naproxen USP per 5 mL and the following inactive ingredients: FD&C Yellow #6, fumaric acid, imitation orange flavor, imitation pineapple flavor, magnesium aluminum silicate, methylparaben, purified water, sodium chloride, sorbitol solution and sucrose. It has a sodium content of 39.3 mg/5 mL, 1.71 mEq/5 mL, with a pH range of 2.2 to 3.7.

Used for

Nycopren is used to treat diseases such as: Ankylosing Spondylitis, Aseptic Necrosis, Back Pain, Bursitis, Chronic Myofascial Pain, Costochondritis, Diffuse Idiopathic Skeletal Hyperostosis, Dysautonomia, Fever, Frozen Shoulder, Gout, Acute, Headache, Juvenile Rheumatoid Arthritis, Muscle Pain, Neck Pain, Osteoarthritis, Pain, Period Pain, Radiculopathy, Rheumatoid Arthritis, Sciatica, Spondylolisthesis, Tendonitis, Transverse Myelitis.

Side Effect

Possible side effects of Nycopren include: nausea or vomiting; confusion about identity, place, and time; indigestion; late appearance of rash with or without weeping blisters that become crusted, especially in sun-exposed areas of skin, may extend to unexposed areas; back or leg pains.

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Serious side effects

Although people can buy low-dose Nycopren without a prescription, it is not safe for everyone.

People with serious heart conditions, such as heart disease, cerebrovascular disease, and congestive heart failure, may experience severe side effects from taking Nycopren.

Severe side effects of Nycopren include:

People with high blood pressure should only take Nycopren cautiously.

Nycopren can cause sodium retention in the kidneys, which can result in increased blood pressure. A person with high blood pressure should consult their doctor before taking Nycopren.

Gastrointestinal side effects of taking Nycopren can be severe. Bleeding in the stomach, the formation of ulcers, and stomach or intestinal blockages can occur when taking Nycopren. Most often, older adults are the most vulnerable age group for gastrointestinal side effects.

People who have a history of ulcers or gastrointestinal bleeding have a 10-fold higher risk for developing a bleed when taking Nycopren. For these individuals, even short-term treatment can be risky.

Risks of Ibuprofen vs. Nycopren

Both ibuprofen and Nycopren have a lower risk of bleeding compared to other NSAIDs, but both should be taken with food or milk to reduce the risk of stomach upset. Risks are similar, and neither should be taken during pregnancy. People who have cardiovascular disease, particularly those who recently had a heart attack or cardiac bypass surgery, are at the greatest risk for cardiovascular adverse events associated with NSAIDs, warns the FDA. Physicians frequently recommend acetaminophen as an OTC pain reliever for patients with cardiovascular issues.

SOURCES & RESOURCES

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Ibuprofen vs. Nycopren

Ibuprofen (Motrin, Advil) and Nycopren (Aleve) are both available under generic/store-brand formulations, as well as their original brand names. Although some people do report that generics work differently for them than brand drugs, the FDA requires generic formulations to perform similarly to brands. They acknowledge a possible slight variation at times, just as between batches of the brand medicine, but the FDA monitors them closely. Any undesired effects should be reported to the FDA.

THE HISTORY OF IBRUPROFEN AND NAPROXEN

According to Wikipedia, ibuprofen was discovered in 1961 by Stewart Adams and initially marketed as Brufen. It was first sold in 1969 in the United Kingdom and in the United States in 1974. Ibuprofen is on the World Health Organization’s List of Essential Medicines, the most effective and safe medicines needed in a health system.

The company Syntex first marketed Nycopren in 1976 as the prescription drug Naprosyn. They sold Nycopren sodium under the brand name Anaprox in 1980. It remains a prescription-only drug in much of the world. In the United States, however, the FDA approved it as an over-the-counter (OTC) drug in 1994.

One decision-maker when it comes to ibuprofen vs. Nycopren may be how long the pain relief is expected to last. Nycopren lasts longer than ibuprofen. The half-life of ibuprofen is two to four hours, while Nycopren is 12 to 17 hours. (Half-life is when half the original dose is still circulating in your bloodstream.) In layman’s terms, you take ibuprofen once every four to six hours, while Nycopren is only repeated once every eight to 12 hours.

According to iodine.com, ibuprofen relieves pain, fever, and swelling. Nycopren is similar, relieving pain, fever, and inflammation. Ibuprofen is available for children, but Nycopren is not.

Before taking Nycopren

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking Nycopren, it is important that your doctor or pharmacist knows:

  • If you have asthma or any other allergic disorder.
  • If you have ever had a stomach or duodenal ulcer, or if you have an inflammatory bowel disorder such as Crohn's disease or ulcerative colitis.
  • If you are pregnant, trying for a baby, or breast-feeding.
  • If you are over 65 years of age.
  • If you have liver or k >

Nycopren Overdose

An overdose of Nycopren may cause:

  • Dizziness
  • Drowsiness
  • Stomach pain
  • Vomiting
  • Trouble breathing

If you think you have taken an overdose or if someone else may have overdosed on Nycopren, call a poison control center at 1-800-222-1222 or call 9-1-1.

Nycopren is also available in enteric-coated tablets. These tablets release Nycopren in the intestine rather than in the stomach. This formulation helps prevent gastrointestinal side effects that manufacturers have sometimes associated with Nycopren. Similarly to regular Nycopren, enteric-coated tablets come in tablets of 250 mg, 375 mg, and 500 mg.

Nycopren is available as tablets, liquid capsules, and in a liquid form.

The dose of Nycopren that a person requires depends on why they are using the medication. A general rule is to use the lowest effective dose for the shortest possible duration. This dosing helps prevent side effects from occurring.

Doctors advise people to take Nycopren and other NSAIDs with food to prevent gastrointestinal side effects.

IMPORTANT WARNING:

People who take nonsteroidal anti-inflammatory drugs (NSAIDs) (other than aspirin) such as Nycopren may have a higher risk of having a heart attack or a stroke than people who do not take these medications. These events may happen without warning and may cause death. This risk may be higher for people who take NSAIDs for a long time. Do not take an NSAID such as Nycopren if you have recently had a heart attack, unless directed to do so by your doctor. Tell your doctor if you or anyone in your family has or has ever had heart disease, a heart attack, or a stroke, if you smoke, and if you have or have ever had high cholesterol, high blood pressure, or diabetes. Get emergency medical help right away if you experience any of the following symptoms: chest pain, shortness of breath, weakness in one part or side of the body, or slurred speech.

If you will be undergoing a coronary artery bypass graft (CABG; a type of heart surgery), you should not take Nycopren right before or right after the surgery.

NSAIDs such as Nycopren may cause ulcers, bleeding, or holes in the stomach or intestine. These problems may develop at any time during treatment, may happen without warning symptoms, and may cause death. The risk may be higher for people who take NSAIDs for a long time, are older in age, have poor health, or who drink three or more alcoholic drinks per day while taking Nycopren. Tell your doctor if you take any of the following medications: anticoagulants (''blood thinners'') such as warfarin (Coumadin, Jantoven); aspirin; other NSAIDs such as ibuprofen (Advil, Motrin) and ketoprofen; oral steroids such as dexamethasone, methylprednisolone (Medrol), and prednisone (Rayos); selective serotonin reuptake inhibitors (SSRIs) such as citalopram (Celexa), fluoxetine (Prozac, Sarafem, Selfemra, in Symbyax), fluvoxamine (Luvox), paroxetine (Brisdelle, Paxil, Pexeva), and sertraline (Zoloft); or serotonin norepinephrine reuptake inhibitors (SNRIs) such as desvenlafaxine (Khedezla, Pristiq), duloxetine (Cymbalta), and venlafaxine (Effexor XR). Also tell your doctor if you have or have ever had ulcers, bleeding in your stomach or intestines, or other bleeding disorders. If you experience any of the following symptoms, stop taking Nycopren and call your doctor: stomach pain, heartburn, vomit that is bloody or looks like coffee grounds, blood in the stool, or black and tarry stools.

Keep all appointments with your doctor and the laboratory. Your doctor will monitor your symptoms carefully and will probably order certain tests to check your body's response to Nycopren. Be sure to tell your doctor how you are feeling so that your doctor can prescribe the right amount of medication to treat your condition with the lowest risk of serious side effects.

Your doctor or pharmacist will give you the manufacturer's patient information sheet (Medication Guide) when you begin treatment with prescription Nycopren and each time you refill your prescription. Read the information carefully and ask your doctor or pharmacist if you have any questions. You can also visit the Food and Drug Administration (FDA) website (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) or the manufacturer's website to obtain the Medication Guide.

Q: Does Nycopren cause anemia?

A: Nycopren (Aleve, Naprosyn) belongs to a class of drugs called non-steroidal anti-inflammatory drugs (NSAIDs). NSAIDs work by blocking substances in the body that cause pain and inflammation. Nycopren is used to treat fever, pain, and inflammation caused by a wide variety of conditions, including arthritis, bursitis, gout, headache, ankylosing spondylitis, tendonitis, menstrual cramps, and minor injuries. Common side effects of Nycopren include nausea, stomach upset, heartburn, bloating, gas, diarrhea, constipation, dizziness, drowsiness, blurred vision, and ringing in the ears. A search of a drug database shows that anemia can occur in up to 10 percent of patients taking NSAIDs, including Nycopren. This would be considered a frequent or common side effect. Consult with your doctor if you are concerned about anemia or if you are experiencing symptoms of anemia, such as fatigue, pale skin, coldness, or dizziness. This is not a complete list of risks or side effects that can occur with Nycopren or any other NSAID. For more specific information, consult with your doctor or local pharmacist for guidance based on your health status and current medications, particularly before taking any action. Sarah Lewis, PharmD

Getting the most from your treatment

  • Your doctor will try to prescribe you the lowest dose for the shortest time in order to reduce the risk of side-effects. If you need to take Nycopren for a long time, your doctor may want to prescribe another medicine along with it to protect your stomach from irritation. Alternatively, you may be prescribed a brand of Nycopren which already contains a protective medicine. An example of a combination brand is Vimovo® which contains Nycopren and esomeprazole.
  • Try to keep any regular appointments with your doctor. This is so your doctor can check on your progress, and is especially important if you are taking Nycopren for a long-term condition.
  • If you have asthma, symptoms such as wheeze or breathlessness can be made worse by anti-inflammatories such as Nycopren. If this happens to you, you should stop taking the tablets and see your doctor as soon as possible.
  • If you buy any medicines, check with a pharmacist that they are safe to take with an anti-inflammatory like Nycopren. This is because you should not take these tablets with any other anti-inflammatory painkiller, some of which are available in cold and flu remedies which can be bought over the counter.
  • If you are having an operation or dental treatment, tell the person carrying out the treatment which medicines you are taking.

Headaches

Using Nycopren to relieve pain from headaches and migraine headaches is controversial.

People can try taking 550 mg of Nycopren sodium every 12 hours and may increase it to 825 mg if needed. The daily dose should not exceed 1,375 mg.

Nycopren sodium is degraded more slowly than regular Nycopren and other NSAIDs. This means that Nycopren sodium should remain active for longer than other anti-inflammatory drugs.

However, after 2 hours, headache pain relief is lower with Nycopren sodium than with other NSAIDs.

Although Nycopren can be used to reduce the pain of headaches and migraine headaches, other NSAIDs may provide better relief.

What happens if I miss a dose?

Since Nycopren is sometimes used only when needed, you may not be on a dosing schedule. If you are on a schedule, use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.


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