Nidazyl gel

Nidazyl

  • Active Ingredient: Metronidazole
  • 500 mg, 400 mg, 250 mg, 200 mg
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What is Nidazyl?

The active ingredient of Nidazyl brand is metronidazole. Metronidazole is an antibiotic that fights bacteria.

Used for

Nidazyl is used to treat diseases such as: Amebiasis, Aspiration Pneumonia, Bacteremia, Bacterial Infection, Bacterial Vaginitis, Balantidium coli, Bone infection, Clostridial Infection, Crohn's Disease, Acute, Crohn's Disease, Maintenance, Deep Neck Infection, Dental Abscess, Dientamoeba fragilis, Diverticulitis, Dracunculiasis, Endocarditis, Giardiasis, Helicobacter Pylori Infection, Intraabdominal Infection, Joint Infection, Lemierre's Syndrome, Meningitis, Nongonococcal Urethritis, Pelvic Inflammatory Disease, Peritonitis, Pneumonia, Pouchitis, Pseudomembranous Colitis, Skin or Soft Tissue Infection, STD Prophylaxis, Surgical Prophylaxis, Trichomoniasis.

Side Effect

Possible side effects of Nidazyl include: stomach and back pain (severe); headache; runny nose; continuing diarrhea; sores, ulcers, or white spots on the lips or in the mouth; ear congestion; swollen glands.

How to Buy Nidazyl lotion online?

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Before taking Nidazyl,

  • tell your doctor and pharmacist if you are allergic to Nidazyl, secnidazole (Solosec), tinidazole (Tindamax), any other medications, or any of the ingredients in Nidazyl preparations. Ask your pharmacist for a list of the ingredients.
  • tell your doctor if you are taking or have taken disulfiram (Antabuse). Your doctor may tell you not to take Nidazyl if you are taking disulfiram or have taken it within the past 2 weeks.
  • tell your doctor and pharmacist what prescription, nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: anticoagulants ('blood thinners') such as warfarin (Coumadin, Jantoven), busulfan (Busulfex, Myleran), cimetidine (Tagamet HB), lithium (Lithobid), phenobarbital, and phenytoin (Dilantin, Phenytek).
  • tell your doctor if you have or have ever had Crohn's disease, or blood, kidney, or liver disease.
  • tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking Nidazyl, call your doctor. Women who are pregnant generally should not take Nidazyl during the first trimester (first 3 months) of pregnancy.
  • do not drink alcoholic beverages or take products with alcohol or propylene glycol while taking this medication and for at least 3 days after your final dose. Alcohol and propylene glycol may cause nausea, vomiting, stomach cramps, headache, sweating, and flushing (redness of the face) when taken with Nidazyl.

What Is Metron >

Nidazyl is the generic form of the brand name drug Flagyl, which is used to treat bacterial infections of the skin, vagina, stomach, joints, or respiratory tract.

The drug is sometimes used with other medicines to treat stomach ulcers.

Nidazyl is an antibiotic, which works by killing bacteria in your body.

The Food and Drug Administration (FDA) first approved Nidazyl in 1963. It's manufactured as Flagyl by the G.D. Searle division of Pfizer Inc.

Warnings

  • Animal data have shown possible carcinogenic effect.
  • This medication contains Nidazyl. Do not take Flagyl, Flagyl ER, or Flagyl IV RTU if you are allergic to Nidazyl or any ingredients contained in this drug.

Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center immediately.

What is metron >

Nidazyl is an antibiotic that fights bacteria.

Nidazyl is used to treat bacterial infections of the vagina, stomach or intestines, liver, skin, joints, brain, heart, and respiratory tract. Metrogel (topical Nidazyl) is also used to treat rosacea, a skin condition. Vaginal Nidazyl gel is also used to treat bacterial infections of the vagina.

Nidazyl will not treat a vaginal yeast infection.

Alcoholic Beverages

Abdominal cramps, nausea, vomiting, headaches, and flushing may occur if alcoholic beverages or products containing propylene glycol are consumed during or following Nidazyl therapy (see CONTRAINDICATIONS).

Why is Nidazyl prescribed to patients?

  • Flagyl is used to treat parasitic infections including Giardia infections of the small intestine, amebic liver abscess, and amebic dysentery (infection of the colon causing bloody diarrhea), bacterial vaginosis, trichomonas vaginal infections, and carriers of trichomonas (both sexual partners) who do not have symptoms of infection.
  • Flagyl is also used alone or in combination with other antibiotics in treating abscesses in the liver, pelvis, abdomen, and brain caused by susceptible anaerobic bacteria.
  • Flagyl is also used in treating infection of the colon caused by a bacterium called C. difficile. Many commonly-used antibiotics can alter the type of bacteria that inhabit the colon. C. difficile is an anaerobic bacterium that can infect the colon when the normal types of bacteria in the colon are inhibited by common antibiotics. This leads to inflammation of the colon (pseudomembranous colitis) with severe diarrhea and abdominal pain.)
  • Flagyl also is used in combination with other drugs to treat Helicobacter pylori (H. pylori) that causes stomach or intestinal ulcers.
  • Flagyl topical gel is used for treating acne rosacea.
  • Flagyl vaginal gel is used for treating bacterial vaginosis.

What other information should I know?

Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your response to Nidazyl.

Before having any laboratory test, tell your doctor and the laboratory personnel that you are taking Nidazyl.

Do not let anyone else take your medication. Your prescription is probably not refillable. If you still have symptoms of infection after you finish the Nidazyl, call your doctor.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

More common side effects

The most common side effects that can occur while taking Nidazyl tablets or capsules include:

  • headache
  • loss of appetite
  • vomiting
  • diarrhea
  • heartburn
  • cramps in your abdomen
  • constipation
  • metallic taste in your mouth
  • yeast infection
  • vaginal discharge

How to use Nidazyl

Take this medication by mouth as directed by your doctor. To prevent stomach upset, take this medication with food or a full glass of water or milk. The dosage is based on your medical condition and response to treatment.

For the best effect, take this antibiotic at evenly spaced times. To help you remember, take this medication at the same time(s) every day.

Continue to take this medication until the full prescribed amount is finished, even if symptoms disappear after a few days. Stopping the medication too early may result in a return of the infection.

Tell your doctor if your condition lasts or gets worse.

Nidazyl and Other Interactions

Nidazyl may make your skin more sensitive to sunlight.

Avoid prolonged exposure to the sun and wear sunscreen, protective clothing, and sunglasses when outdoors.

The medicine may also make you dizzy. Don't drive or operate machinery until you know how Nidazyl affects you.

What if I take too much?

Accidentally taking an extra dose of Nidazyl is unlikely to harm you or your child.

Speak to your pharmacist or doctor if you're worried or you take more than 1 extra dose.

Contraindications

  • Hypersensitivity to Nidazyl or other nitroimidazoles (although cautious desensitization has been applied)
  • Pregnancy, 1st trimester (controversial)
  • Use of disulfiram within past 2 weeks; use of alcohol during therapy or within 3 days of discontinuing therapy

Effects of Drug Abuse

  • No information available

  • See "What Are Side Effects Associated with Using Nidazyl?"

  • Encephalopathcy, seizures, aseptic meningitis, and neuropathies reported with increase in dose and chronic therapy
  • Superinfection may occur with prolonged use
  • See "What Are Side Effects Associated with Using Nidazyl?"

  • Encephalopathy, seizures, aseptic meningitis, and neuropathies reported with increase in dose and chronic therapy
  • Superinfection may occur with prolonged use
  • Severe hepatic impairment; administer lower doses with caution
  • Use with caution; potential accumulation in end stagerenal disease; supplemental doses may be needed in patients receiving hemodialysis
  • Use with caution in history of blood dyscrasias, heart failure, hepatic failure, H. pylori infection, renal impairment
  • Avoid alcohol while taking medication and for at least 1 day after discontinuation
  • Antiandrogen: May cause gynecomastia
  • Known or previously unrecognized candidiasis may present more prominent symptoms during therapy with Nidazyl Injection and requires treatment with a candicidal agent

  • Nidazyl may be acceptable for use during pregnancy. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk. There are published data from case-control studies, cohort studies, and 2 meta-analyses that included more than 5000 pregnant women who used Nidazyl systemically during pregnancy
  • Many studies included first trimester exposures. One study showed an increased risk of cleft lip, with or without cleft palate, in infants exposed to Nidazyl in utero; however, these findings were not confirmed
  • In addition, more than 10 randomized, placebo-controlledclinical trials that together enrolled over 5000 pregnant women assessed the possible effect of systemic antibiotic treatment (including with Nidazyl) for bacterial vaginosis on the incidence of preterm delivery; most studies did not show an increased risk of congenital anomalies or other adverse fetal outcomes following Nidazyl exposure during pregnancy
  • Three studies conducted to assess the risk of infantcancer following systemic Nidazyl exposure during pregnancy did not show an increased risk; however, the ability of these studies to detect such a signal was limited.
  • Nidazyl is excreted in human milk; it is not recommended for use while breastfeeding
  • Following oral administration, concentrations in human milk are similar to concentrations in plasma
  • Potential for tumorigenicity shown in animal studies; a decision should be made whether to discontinue nursing or to discontinue Nidazyl; breastfeeding women may choose to pump and discard milk for the duration of therapy and for 24 hours after therapy ends and to feed her infant stored human milk or formula


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