Nervosal tablets

Nervosal

  • Active Ingredient: Fluoxetine
  • 20 mg, 10 mg
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What is Nervosal?

The active ingredient of Nervosal brand is fluoxetine. Fluoxetine is a selective serotonin reuptake inhibitors (SSRI) antidepressant. Fluoxetine affects chemicals in the brain that may be unbalanced in people with depression, panic, anxiety, or obsessive-compulsive symptoms. C17H18F3NO•HCl M.W. 345.79 Fluoxetine hydrochloride, USP is a white to off-white crystalline solid with a solubility of 14 mg/mL in water. Each tablet contains Fluoxetine hydrochloride, USP equivalent to 10 mg (32.3 μmol) of Fluoxetine. In addition, each tablet also contains the following inactive ingredients: D&C Yellow #10 aluminum lake, FD&C Blue #2 aluminum lake, FD&C Yellow #6 aluminum lake, hypromellose, lactose monohydrate, magnesium stearate, microcrystalline cellulose, polyethylene glycol, povidone, pregelatinized corn starch, talc, and titanium dioxide.

Used for

Nervosal is used to treat diseases such as: Anxiety and Stress, Binge Eating Disorder, Body Dysmorphic Disorder, Borderline Personality Disorder, Bulimia, Depression, Dissociative Identity Disorder, Dysautonomia, Fibromyalgia, Hot Flashes, Intermittent Explosive Disorder, Major Depressive Disorder, Obsessive Compulsive Disorder, PANDAS Syndrome, Panic Disorder, Persistent Depressive Disorder, Postpartum Depression, Premature Ejaculation, Premenstrual Dysphoric Disorder, Schizoaffective Disorder, Somatoform Pain Disorder, Trichotillomania, Vulvodynia.

Side Effect

Possible side effects of Nervosal include: bloody, black or tarry stools; inability to sit still; feeling of warmth or heat; chest pain or discomfort; difficulty with concentration.

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Q: Can Prozac cause hair loss?

A: Hair loss, also called alopecia, is a rare but possible side effect of Prozac (Nervosal). It is always a good idea to check with one’s health care provider in matters like this. Here is a link to more Prozac information: //www.everydayhealth.com/drugs/prozac. Gregory Latham, RPh

Princeton's WordNet (0.00 / 0 votes) Rate this definition:

Nervosal, Nervosal hydrocholor >(noun)

a selective-serotonin reuptake inhibitor commonly prescribed as an antidepressant (trade names Prozac or Sarafem); it is thought to work by increasing the activity of serotonin in the brain

What are the side effects of Nervosal?

Nervosal, as with most antidepressants, can cause nausea, headaches, anxiety, insomnia, drowsiness, and loss of appetite. Nervosal has been implicated in serious skin rashes and vasculitis (inflammation of small blood vessels). Increased blood pressure can occur, and blood pressure should be monitored. Seizures have been reported as has sexual dysfunction. Some patients may experience withdrawal reactions upon stopping Nervosal. Symptoms of withdrawal include anxiety, nausea, nervousness, and insomnia. The dose of Nervosal should be gradually reduced when therapy is discontinued. Nervosal and other antidepressants have been associated with angle closure attacks in people with narrow angle glaucoma.

Antidepressants increased the risk of suicidal thinking and behavior in short-term studies in children and adolescents with depression and other psychiatric disorders. Anyone considering the use of Nervosal or any other antidepressant in a child or adolescent must balance this risk of suicide with the clinical need. Patients who are started on therapy should be closely observed for clinical worsening, suicidal thoughts, or unusual changes in behavior.

Urgent advice: Call a doctor straight away if:

You've taken too much Nervosal by accident and experience symptoms such as:

  • being sick (vomiting)
  • shaking
  • feeling sleepy
  • feeling agitated
  • heart problems
  • lung problems
  • fits (seizures)

If you need to go to a hospital accident and emergency (A&E) department, do not drive yourself - get someone else to drive you or call for an ambulance.

Take the Nervosal packet, or the leaflet inside it, plus any remaining medicine with you.

Like all medicines, Nervosal can cause side effects in some people, but many people have no side effects or only minor ones. Some of the common side effects of Nervosal will gradually improve as your body gets used to it.

1. About Nervosal

Nervosal is a type of antidepressant known as an SSRI (selective serotonin reuptake inhibitor).

It is often used to treat depression, and also sometimes obsessive compulsive disorder and bulimia.

Nervosal helps many people recover from depression, and it has fewer unwanted effects than older antidepressants.

Nervosal is available only on prescription. It comes as tablets and capsules.

8. Cautions with other medicines

Some medicines and Nervosal can interfere with each other and increase the chances of you having side effects.

Tell your doctor if you're taking these medicines before you start Nervosal:

  • any medicines that affect your heartbeat - as Nervosal can speed up or change your heartbeat
  • any other medicines for depression. Some rarely used antidepressants can interfere with Nervosal to cause very high blood pressure even when they have been stopped for a few weeks.

Initiate treatment with PROZAC 10 mg/day. After one week, increase the dose to 20 mg/day. Consider a dose increase after several weeks if no clinical improvement is observed. Nervosal doses above 60 mg/day have not been systematically evaluated in patients with Panic Disorder. In the controlled clinical trials of Nervosal supporting its effectiveness in the treatment of Panic Disorder, patients were administered Nervosal doses in the range of 10 to 60 mg/day . The most frequently administered dose in the 2 flexible-dose clinical trials was 20 mg/day.

Periodically reassess to determine the need for continued treatment.

Nervosal, also known by trade names Prozac and Sarafem among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It is used for the treatment of major depressive disorder, obsessive–compulsive disorder (OCD), bulimia nervosa, panic disorder, and premenstrual dysphoric disorder.

Prozac Warnings

Prozac and other antidepressants are required to carry a black box warning due to the increased risk of suicide when taking the medicine.

Prozac may increase suicidal thoughts or actions in children, teenagers, and young adults within the first several months of treatment or after a change in dose.

Call your doctor immediately if you have any unusual changes in behavior or mood while on Prozac, including:

  • Thoughts about suicide or dying, or suicide attempts
  • New or worsening depression or anxiety
  • Feeling very agitated or restless
  • Panic attacks
  • Difficulty sleeping
  • New or worse irritability
  • Being aggressive, angry, or violent
  • Acting on dangerous impulses
  • Extreme increase in activity and talking
  • Decreased need for sleep

Before taking Prozac, tell your doctor if you have a history of seizures; bipolar disorder; liver disease; heart problems, including heart rhythm problems; diabetes; glaucoma; or thoughts of suicide or attempted suicide.

You may not feel the full benefits of Prozac for 4 to 6 weeks or longer after starting the medication.

Before stopping Prozac, talk to your doctor. Stopping suddenly can cause serious side effects. Your doctor will help you safely stop the medication.

Don't take Prozac or other forms of Nervosal if you're allergic to Nervosal or any of the inactive ingredients in the various formulations. Cases of severe allergic reactions have been reported and could result in death.

If you are taking a monoamine oxidase inhibitor (MAOI) or if you took an MAOI in the past 14 days, then don't use Prozac. A dangerous drug interaction could occur that may result in death.

Avoid operating heavy machinery, driving a motor vehicle, or performing other dangerous activities until you know how Prozac affects you.

The drug can cause sleepiness and may worsen your ability to make decisions, think clearly, or react quickly.

There is limited information regarding the long-term effects of Prozac on the development and maturation of children and adolescents.

Talk to your child's doctor about monitoring their height and weight when they are taking Prozac.

Q: Is Prozac for insomnia?

A: Prozac (Nervosal) is not indicated for insomnia treatment by the U.S. Food and Drug Administration (FDA). Prozac is approved by the FDA for the treatment of several other medical conditions including depression, obsessive-compulsive disorder, bulimia nervosa and panic disorder. During clinical trials, one of the most commonly observed adverse reactions in patients being treated with Prozac, for any indication, was insomnia. During placebo-controlled clinical trials for major depressive disorder, Prozac caused insomnia in 16% of patients being evaluated. In trials evaluating Prozac for obsessive-compulsive disorder, 28% of patients reported insomnia as an adverse reaction associated with treatment. During the clinical trials of bulimia, 33% of patients reported experiencing insomnia caused by Prozac. Finally, in the clinical studies of patients with panic disorder, Prozac precipitated insomnia in 10% of patients. Overall, for all indications combined, the incidence of Prozac causing insomnia was reported by 19% of patients. According to the prescribing information, insomnia was one of the most common adverse reactions associated with discontinuation of Prozac in patients with bulimia, with 2% of patients discontinuing treatment. Patients should be advised to take Prozac exactly as directed by their health care provider. If patients experience unpleasant or bothersome adverse reactions, such as insomnia, they are also advised not to change their dosing regimen or discontinue treatment without consulting with their health care provider.

Is Nervosal safe to take if I'm pregnant or breastfeeding?

Nervosal is excreted in breast milk. Therefore, use of Nervosal while nursing is not recommended.

Q: Can Prozac 60 mg per day cause severe fatigue, daytime sleepiness, and increased snoring?

A: Prozac (Nervosal) is classified as a selective serotonin reuptake inhibitor (SSRI) antidepressant. Prozac is approved for the treatment of depression, binge eating and vomiting in moderate to severe bulimia nervosa, obsessive compulsive disorder (OCD), premenstrual dysphoric disorder (PMDD), panic disorder and in combinations with other medications to treat bipolar depression. According to medical references, somnolence (drowsiness) is a possible side effect associated with the use of Prozac. Somnolence has been reported with an incidence of 5% to 17% of studied patients taking the medication. If you think that you are experiencing a side effect from your medication, talk with your physician. Do not stop taking or change the dose of your medication without first talking to your physician. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. Jen Marsico, RPh

Q: What is the best way to stop taking Prozac 40 mg a day?

A: You would want to work with your physician to come up with a gradual tapering of the dose over time to discontinue this medication. An abrupt cessation of Prozac (Nervosal) may cause a discontinuation syndrome including headache, lethargy, GI upset, insomnia, nightmares, dizziness, vertigo, tremor, agitation, anxiety, irritability, and confusion. You can also find helpful information on depression at //www.everydayhealth.com/depression/guide/.

Why is this medication prescribed?

Nervosal (Prozac) is used to treat depression, obsessive-compulsive disorder (bothersome thoughts that won't go away and the need to perform certain actions over and over), some eating disorders, and panic attacks (sudden, unexpected attacks of extreme fear and worry about these attacks). Nervosal (Sarafem) is used to relieve the symptoms of premenstrual dysphoric disorder, including mood swings, irritability, bloating, and breast tenderness. It is also used along with olanzapine (Zyprexa) to treat depression that did not respond to other medications and episodes of depression in people with bipolar I disorder (manic-depressive disorder; a disease that causes episodes of depression, episodes of mania, and other abnormal moods). Nervosal is in a class of medications called selective serotonin reuptake inhibitors (SSRIs). It works by increasing the amount of serotonin, a natural substance in the brain that helps maintain mental balance.

Q: Can you tell me more about Prozac?

A: Prozac (Nervosal) is used to treat depression or obsessive-compulsive disorder (OCD) in adults and children. It is also used to treat bulimia and panic disorder in adults. It may also be used for other conditions as determined by your doctor. Prozac is a selective serotonin reuptake inhibitor (SSRI). It works by restoring the balance of serotonin, a natural substance in the brain, which helps to improve certain mood problems. All medicines may cause side effects, but many people have no, or minor, side effects with Nervosal. The most common side effects of Prozac are drowsiness, dizziness, anxiety, abnormal dreams, decreased sexual desire or ability, diarrhea, dry mouth, flu-like symptoms, flushing, sweating, loss of appetite, nausea, and trouble sleeping. Some medicines may interact with Nervosal. Tell your physician if you are taking any other medicines. Do not suddenly stop taking Nervosal without checking with your doctor. Withdrawal symptoms such as mood changes, numbness or tingling of the skin, dizziness, confusion, headache, trouble sleeping, or unusual tiredness may occur. For more information visit the Everyday Health Depression Center at: //www.everydayhealth.com/depression/guide/ or to submit another question return to //www.everydayhealth.com/drugs/. Burton Dunaway, PharmD

Q: Does Prozac cause weight gain?

A: Prozac (Nervosal) is classified as a selective serotonin reuptake inhibitor (SSRI) antidepressant. Prozac is approved for the treatment of depression, binge-eating, and vomiting in patients with bulimia, obsessive compulsive disorder (OCD), premenstrual dysphoric disorder (PMDD), panic disorder and with other medication to treat bipolar disorder. According to medical references, weight gain is a possible reported side effect of Prozac. Increased appetite and weight loss are also listed side effects of the medication. These are not a complete list of side effects associated with the use of Prozac. Drugs can cause weight gain in several different ways. Some can increase appetite or make you crave certain types of foods like those high in carbohydrates or fat. Other medications may slow down metabolism or cause fluid retention. However, the effect of prescription drugs on body weight is complex. Some drugs have no effect on weight, while others cause weight gain or weight loss. Also, the same medications can cause weight gain in certain individuals and weight loss in others. There are also drugs that initially cause weight loss and then lead to weight gain with long-term use. Most prescription medications associated with changes in body weight affect the central nervous system. These include antidepressants like monoamine oxidase inhibitors (MAOIs), tricyclic antidepressants, and selective serotonin reuptake inhibitors (SSRIs). Mood stabilizers (lithium, valproic acid), antipsychotics, and anticonvulsants have also been linked with weight gain. Other drugs that have been reported to cause weight gain include diabetes medications (insulin, sulfonylureas, and thiazolidinediones), antihypertensive drugs, certain hormonal contraceptives, corticosteroids, antihistamines, some chemotherapy regimens, and antiretroviral protease inhibitors. If you think a drug you are taking is causing weight gain, tell your health care provider. Do not stop any medication or change the dose without first talking to your provider. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. Jen Marsico, RPh

Q: Does Prozac have any long-term health risks?

A: Prozac (Nervosal) is a selective serotonin reuptake inhibitor (SSRI) antidepressant used to treat major depressive disorder, eating disorders, obsessive-compulsive disorder, premenstrual dysphoric disorder, and panic disorder. Many patients have been on Prozac for many years without adverse effects. Prozac is considered safe to use long term if needed. Warnings from the prescribing information for Prozac include the following. Prozac like all antidepressants can increase the risk of suicidal thinking and behavior in children and young adults, especially when the medication is first started. Prozac may worsen psychosis in some patients or cause mania in patients with bipolar disorder. Prozac should be used with caution in patients with seizure disorders, liver or kidney disease, and history of heart disease. Prozac may cause weight changes, sleep changes, and sexual dysfunction. Patients who have been on Prozac long term and wish to stop the medication will need to taper the dose down to prevent withdrawal symptoms. This is not a complete list of the side effects associated with Prozac. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. When your doctor prescribes a new medication, be sure to discuss all your prescription and over-the-counter drugs, including dietary supplements, vitamins, botanicals, minerals, and herbals, as well as the foods you eat. Always keep a current list of the drugs and supplements you take and review it with your health care providers and your pharmacist. If possible, use one pharmacy for all your prescription medications and over-the-counter products. This allows your pharmacist to keep a complete record of all your prescription drugs and to advise you about drug interactions and side effects. Laura Cable, Pharm.D., BCPS

Q: I'm currently taking Prozac 10 mg and I'm wondering if this could be impacting my weight, the swollenness/redness in my face?

A: According to the literature available for Prozac (Nervosal), changes in weight were a reported side effect. The studies have shown that various types of dermatologic side effects were reported. If you are experiencing unusual or bothersome symptoms while taking Prozac (Nervosal), you may want to speak to your health care provider to determine the cause. For additional information regarding Prozac (Nervosal) you may want to visit our Web site: //www.everydayhealth.com/drugs/prozac.


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