Nerfin Brand Names
Nerfin may be found in some form under the following brand names:
What is Nerfin?
Nerfin is a progestin (a form of progesterone), a female hormone that helps regulate ovulation (the release of an egg from an ovary) and menstrual periods.
Nerfin is used to treat conditions such as absent or irregular menstrual periods, or abnormal uterine bleeding. Nerfin is also used to decrease the risk of endometrial hyperplasia (a condition that may lead to uterine cancer) while taking estrogens.
Nerfin is also used to prevent overgrowth in the lining of the uterus in postmenopausal women who are receiving estrogen hormone replacement therapy.
Nerfin may also be used for purposes not listed in this medication guide.
- Patients should be informed that Nerfin contraceptive does not protect against HIV infection and other sexually transmitted diseases
Nerfin treats heavy menstrual bleeding, absence of menstruation, and can be used to prevent pregnancy. May cause weight gain.
How to take Nerfin
- Before you start the treatment, read the manufacturer's printed information leaflet from ins >
Uses of Nerfin
Nerfin (oral) is a prescription medicine used to:
- treat menstrual periods that have stopped or to treat abnormal uterine bleeding.
- reduce the chances of getting cancer of the uterus in women after menopause.
Nerfin (injectable) is also used to:
- prevent pregnancy (long-acting birth control)
- relieve pain from endometriosis (subcutaneous form)
- relieve symptoms of advanced endometrial cancer (intramuscular form)
- relieve symptoms of kidney cancer (intramuscular form)
This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.
Before taking Nerfin
Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking Nerfin tablets, it is important that your doctor knows:
- If you are pregnant or breastfeeding.
- If you have a problem with your arteries, called arterial disease.
- If you have a heart condition.
- If you have any of the following conditions: migraines, asthma, epilepsy, diabetes, or high blood pressure.
- If you have any vaginal bleeding other than your normal monthly period.
- If you have ever had a blood clot in your legs or lungs.
- If you have had any problems with the way your liver works, or if you have any problems with the way your k >
Last Update: June 6, 2019 .
Desogestrel, Dydrogesterone, Levonorgestrel, Nerfin, Megestrol, Norethindrone, Norgestrel, Norgestimate, Progesterone
Why is this medication prescribed?
Nerfin is used to treat abnormal menstruation (periods) or irregular vaginal bleeding. Nerfin is also used to bring on a normal menstrual cycle in women who menstruated normally in the past but have not menstruated for at least 6 months and who are not pregnant or undergoing menopause (change of life). Nerfin is also used to prevent overgrowth of the lining of the uterus (womb) and may decrease the risk of cancer of the uterus in patients who are taking estrogen. Nerfin is in a class of medications called progestins. It works by stopping the growth of the lining of the uterus and by causing the uterus to produce certain hormones.
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The following side effects have been reported with the use of Nerfin alone:
- Breast tenderness
- Breast milk secretion
- Breakthrough bleeding
- Spotting (minor vaginal bleeding)
- Irregular periods
- Amenorrhea (absence of menstrual periods)
- Vaginal secretions
- Insomnia, sleepiness, fatigue
- Premenstrual syndrome-like symptoms
- Thrombophlebitis (inflamed veins)
- Blood clot
- Itching, hives, skin rash
- Hair loss, hair growth
- Abdominal discomfort
- Increase in weight
- Changes in vision and sensitivity to contact lenses
The following side effects have been reported with the use of Nerfin with an estrogen.
Side effects are grouped by how serious they are and how often they happen when you are treated:
Serious but less common side effects of estrogen include:
- Breast cancer
- Cancer of the uterus
- Heart attack
- Blood clots
- Gallbladder disease
- Ovarian cancer
- High blood pressure
- Liver problems
- High blood sugar
- Enlargement of benign tumors of the uterus ("fibroids")
Some of the warning signs of these serious side effects include:
- Breast lumps
- Unusual vaginal bleeding
- Dizziness and faintness
- Changes in speech
- Severe headaches
- Chest pain
- Shortness of breath
- Pains in your legs
- Changes in vision
- Yellowing of the skin, eyes or nail beds
Call your healthcare provider right away if you get any of these warning signs, or any other unusual symptom that concerns you.
Less serious but common side effects include:
- Breast pain
- Irregular vaginal bleeding or spotting
- Stomach/abdominal cramps, bloating
- Nausea and vomiting
- Hair loss
- Fluid retention
- Vaginal yeast infection
These are not all the possible side effects of Nerfin with or without estrogen. For more information, ask your healthcare provider or pharmacist.
Nerfin injection (depo-provera)
There is no ev >Nerfin injections but theoretically they might. Many neurologists recommended that the frequency of injection for women taking such drugs be increased to every 10 weeks from the usual 12, although there is no evidence that this should be done ( Betts and Crawford, 1998 ; O'Brien and Guillebaud, 2006 ). In adolescent girls, there is some evidence to suggest that Depo-Provera may interfere with the achievement of peak bone mass ( Faculty of Family Planning, 2004 ), a problem also encountered with AEDs such as carbamazepine, phenytoin, barbiturates, and valproate.
What should I discuss with my healthcare prov >
Nerfin can cause birth defects. Do not use if this medicine if you are pregnant. You may need to have a negative pregnancy test before you start this medicine. Tell your doctor right away if you become pregnant, or if you plan to become pregnant soon after you stop using Nerfin.
You should not use Nerfin if you are allergic to it, or if you have:
- unusual vaginal bleeding;
- liver disease;
- a history of breast cancer; or
- a history of heart attack, stroke, or blood clot.
You should not use this medicine for longer than 2 years. Nerfin can decrease the calcium stored in your bones, which may cause bone loss (osteoporosis) when used over long periods of time. Bone loss may not be reversible. Ask your doctor about your specific risk.
To make sure Nerfin is safe for you, tell your doctor if you have:
- kidney disease;
- high blood pressure, congestive heart failure;
- migraine headaches;
- hereditary angioedema;
- breast nodules, or a family history of breast cancer;
- a personal or family history of diabetes;
- low bone mineral density, or a family history of osteoporosis;
- depression, or an eating disorder;
- light, heavy, or irregular menstrual periods;
- a adrenal gland disorder;
- if you have ever had a breast lump, an abnormal mammogram, or bleeding from your nipples; or
- if you drink large amounts of alcohol or if you smoke.
If you are breast-feeding a baby, wait until your baby is at least 6 weeks old before using this medicine.
Studies have shown that using combination hormone therapy, or combination HT (estrogen and progesterone) increases the risk for heart attacks, stroke, breast cancer, dementia, and blood clots. Because of these risks, combination HT should only be used short-term at the lowest possible dose.
Nerfin injection can cause bone loss, which may increase your risk for osteoporosis (weak and thinning bones) and fractures. The medication should not be used for longer than two years unless absolutely necessary as long-term therapy will increase risk of bone loss.
Vaginal bleeding after menopause may be a warning sign of cancer of the uterus (womb). Your health care provider should check any unusual vaginal bleeding to find out the cause.
Do not use estrogens with or without progestins to prevent heart disease, heart attacks, or strokes. Using estrogens with or without progestins may increase your chance of getting heart attacks, strokes, breast cancer, and blood clots.
Using estrogens with or without progestins may increase your risk of dementia, based on a study of women age 65 years or older.
You and your healthcare provider should talk regularly about whether you still need treatment with Nerfin.
Do not start taking Nerfin if you:
- have undiagnosed vaginal bleeding.
- Estrogen plus progestin may increase your chance of getting certain cancers, including cancer of the breast. If you have or have had cancer, talk with your healthcare provider about whether you should use Nerfin.
Nerfin acetate (MPA) is a 17-acetoxyprogesterone compound. Unlike most other synthetic progestins, MPA is structurally most closely related to progesterone, instead of testosterone, and possesses less androgenic activity. MPA is rapidly metabolized in humans to progesterone. The 3-month injectable dosage is 150 mg. The drug is delivered by intramuscular injection into the deltoid or gluteus muscle and is released slowly into the circulation.
MPA is an extremely effective contraceptive with a 1-year pregnancy rate of 0.1% and a 2-year accumulative pregnancy rate of 0.4%. Its primary mechanism of contraceptive action is ovulation inhibition, but it works by increasing the cervical mucus viscosity and creating progestational changes in the endometrium as well.
How should I use Nerfin?
Nerfin is injected into a muscle or under the skin. Nerfin may be given once per week or once every 3 months, depending on why you are using the medicine. Follow your doctor's instructions.
When used for birth control, Nerfin is given by a healthcare provider. For other conditions, you may be shown how to use injections at home. Do not self-inject this medicine if you do not fully understand how to give the injection and properly dispose of used needles and syringes.
You may have breakthrough bleeding while using Nerfin. Tell your doctor if this bleeding continues or is very heavy.
This medicine can cause unusual results with certain medical tests. Tell any doctor who treats you that you are using this medicine.
Your doctor will need to see you on a regular basis while you are using Nerfin. If you use this medicine long-term, your bone density may need to be checked during treatment.
Store at room temperature away from moisture and heat.
Use a disposable needle and syringe only once. Follow any state or local laws about throwing away used needles and syringes. Use a puncture-proof "sharps" disposal container (ask your pharmacist where to get one and how to throw it away). Keep this container out of the reach of children and pets.