Meriestra is available in several forms.
- Tablets, micronized: 0.5mg, 1mg, 2mg;
- Vaginal cream: 0.01%;
- Continuous release skin patch: 14 mcg/day, 0.025 mg/day, 0.0375 mg/day, 0.05 mg/day, 0.1 mg/day, 0.06 mg/day, 0.075 mg/day;
- Topical emulsion: 4.35 mg/1.74 g; Topical Gel: 0.25 mg/0.25 g, 0.5 mg/0.5 g, 1 mg/g;
- Intramuscular oil: 5 mg/mL, 10 mg/mL, 20 mg/mL, 40 mg/mL; Vaginal Ring: 0.05 mg/24 hr, 0.1 mg/24 hr.
Q: Does Meriestra cause weight gain?
A: Estrogens, a group of steroid compounds, are used as part of some oral contraceptives, and in estrogen replacement therapy for postmenopausal women. Common side effects include headache, breast pain, irregular vaginal bleeding or spotting, stomach/abdominal cramps, bloating, nausea and vomiting, and hair loss. Other side effects have been reported with estrogen and/or progestin therapy including increase or decrease in weight. These are not all the possible side effects of estrogen. For a complete list, ask your doctor or pharmacist. For more detailed information, consult with your physician or pharmacist about the potential for side effects based on your specific condition and current medications.
Serious Side Effects of Meriestra
Contact your doctor immediately if you experience any of the following serious side effects:
- Sudden, severe headache
- Sudden, severe vomiting
- Speech problems
- Dizziness or fainting
- Sudden, complete or partial loss of vision or double vision
- Weakness or numbness of an arm or leg
- Crushing chest pain or chest heaviness
- Coughing up blood
- Sudden shortness of breath or difficulty breathing
- Breast lumps or other breast changes
- Nipple discharge
- Difficulty thinking clearly or remembering
- Pain, tenderness, or redness in one leg
- Bulging eyes
- Yellowing of the skin or eyes
- Loss of appetite
- Joint pain
- Stomach tenderness, pain, or swelling
- Hives, rash, or blisters
- Movements that are difficult to control
- Swelling of the eyes, face, lips, tongue, throat, hands, feet, ankles, or lower legs
- Difficulty swallowing
What Other Drugs Interact with Meriestra?
If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first.
Severe Interactions of Meriestra include:
Meriestra has serious interactions with at least 32 different drugs.
Meriestra has moderate interactions with at least 185 different drugs.
Meriestra has mild interactions with at least 34 different drugs.
This information does not contain all possible interactions or adverse effects. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share this information with your doctor and pharmacist. Check with your health care professional or doctor for additional medical advice, or if you have health questions, concerns or for more information about this medicine.
Indications and dosages
➣ Symptoms of menopause, atrophic vaginitis, female hypogonadism, ovarian failure, and osteoporosis
Adults: 0.5 to 2 mg (Meriestra) P.O. daily continuously or cyclically. Or 1 to 5 mg (cypionate) or 10 to 20 mg (valerate) I.M. monthly. Or 50- or 100-mcg/24-hour transdermal patch applied twice weekly (Alora, Estraderm) or weekly (Climara). Or 25-mcg/24-hour patch applied q 7 days (FemPatch) or 37.5- to 100-mcg transdermal patch applied twice weekly (Vivelle). Or 2 to 4 g (0.2 to 0.4 mg) vaginal cream (Meriestra) applied daily for 1 to 2 weeks, then decreased to 1 to 2 g/day for 1 to 2 weeks, then a maintenance dose of 1 g one to three times weekly for 3 weeks, then off for 1 week; repeat cycle once vaginal mucosa has been restored. Or 2-mg vaginal ring q 3 months or 10-mcg vaginal tablet once daily for 2 weeks, then twice weekly.
➣ Postmenopausal breast cancer
Adults: 10 mg P.O. t.i.d. (Meriestra)
Adults: 1 to 2 mg P.O. t.i.d. (Meriestra) or 30 mg I.M. q 1 to 2 weeks (valerate)
Examples of Meriestra in a Sentence
These example sentences are selected automatically from various online news sources to reflect current usage of the word 'Meriestra.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.
To use the Meriestra vaginal cream:
Using the marked applicator provided, measure the prescribed dose of cream.
Lie on your back with your knees drawn up, sit, or stand in a position that allows you comfortable access to the vaginal area. To deliver the medication, gently insert the applicator deep into your vagina and press the plunger downward to its original position.
Clean the applicator by pulling the plunger from the barrel. Wash it with mild soap and warm water.
Have yearly physical exams and examine your breasts for lumps on a monthly basis while using Meriestra.
What special precautions should I follow?
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Q: I started on Meriestra about two weeks ago, and haven't had a period in about a year. I am now bleeding again. How long can I expect this to go on? It's been about 5 days now and shows no sign of stopping. I'm 54 years old.
A: While changes in your periods can be expected on Meriestra, patients should contact their healthcare provider right away for any unusual vaginal bleeding. This could be a sign of a serious side effect. You may also find helpful information at //www.everydayhealth.com/drugs/Meriestra
Before taking this medicine
You should not use this medicine if you are allergic to Meriestra, or if you have:
unusual vaginal bleeding that has not been checked by a doctor;
a history of heart attack, stroke, or blood clot;
an increased risk of having blood clots due to a heart problem or a hereditary blood disorder; or
a history of hormone-related cancer, or cancer of the breast, uterus/cervix, or vagina.
Do not use Meriestra if you are pregnant. Tell your doctor right away if you become pregnant during treatment.
Using this medicine can increase your risk of blood clots, stroke, or heart attack. You are even more at risk if you have high blood pressure, diabetes, high cholesterol, if you are overweight, or if you smoke.
Meriestra should not be used to prevent heart disease, stroke, or dementia, because this medicine may actually increase your risk of developing these conditions.
To make sure this medicine is safe for you, tell your doctor if you have ever had:
liver problems, or prior jaundice caused by pregnancy or taking hormones;
epilepsy or other seizure disorder;
endometriosis or uterine fibroid tumors;
porphyria (a genetic enzyme disorder that causes symptoms affecting the skin or nervous system);
a thyroid disorder; or
high levels of calcium in your blood.
Using Meriestra may increase your risk of cancer of the breast, uterus, or ovaries. Talk with your doctor about this risk.
Meriestra lowers the hormone needed to produce breast milk and can slow breast milk production. Tell your doctor if you are breast-feeding.
PICTURES OF ESTRADIOL PILLS
Below you will find images and specific information on the principal types of Meriestra that exist, including their respective brand name(s), strength, inscription codes and manufacturers.
The information below includes general information and guidelines for patients taking this medication and should never be used to substitute professional medical advice that can be provided by a qualified physician or family doctor.
How should I take Meriestra (Estrace, Gynodiol)?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Meriestra may increase your risk of developing a condition that can lead to uterine cancer. To help lower this risk, your doctor may also want you to take a progestin. Report any unusual vaginal bleeding right away.
Your doctor should check your progress on a regular basis (every 3 to 6 months) to determine whether you should continue this treatment. Self-examine your breasts for lumps on a monthly basis and have a mammogram every year while using Meriestra.
If you need major surgery or will be on long-term bed rest, you may need to stop using this medicine for a short time. Any doctor or surgeon who treats you should know that you are using Meriestra.
Store at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use.
COMMON BRAND(S): Cenestin, Enjuvia, Estrace, Femtrace, Ogen, Premarin
GENERIC NAME(S): Meriestra
OTHER NAME(S): Meriestra Tablet
Estrogens, either used alone or with another hormone (progestin), have rarely caused very serious side effects. Discuss the risks and benefits of hormone treatment with your doctor. Estrogens should not be used to prevent heart disease or dementia.
Estrogens can increase the risk of cancer of the uterus (endometrial cancer). Taking a progestin as directed by your doctor can help decrease this risk. Tell your doctor right away if you have any unusual vaginal bleeding.
In postmenopausal women, estrogens, taken with or without a progestin, increase the risk of cancer of the breast/ovaries, stroke, dementia, and serious blood clots. When used along with a progestin, estrogens also increase the risk of heart disease (such as heart attacks).
The risk for serious side effects may depend on the dose of estrogen and the length of time it is used. Therefore, this medication should be used at the lowest effective dose and for the shortest amount of time. Discuss the use of this medication with your doctor and check with him/her regularly (for example, every 3 to 6 months) to see if you still need to take this medication. If you will be taking this medication long-term, you should have regular complete physical exams (for example, once a year) as directed by your doctor. See also Notes section.
This medication is a female hormone. It is used by women to help reduce symptoms of menopause (such as hot flashes, vaginal dryness). These symptoms are caused by the body making less estrogen. If you are using this medication to treat symptoms only in and around the vagina, products applied directly inside the vagina should be considered before medications that are taken by mouth, absorbed through the skin, or injected.
Certain estrogen products may also be used by women after menopause to prevent bone loss (osteoporosis). However, there are other medications (such as raloxifene, bisphosphonates including alendronate) that are also effective in preventing bone loss and may be safer. These medications should be considered for use before estrogen treatment.
Certain estrogen products may also be used by men and women to treat cancers (certain types of prostate cancer, breast cancer that has spread to other parts of the body) and by women who are not able to produce enough estrogen (for example, due to hypogonadism, primary ovarian failure).