What are some other side effects of Losiral?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
What do I need to tell my doctor BEFORE I take Losiral?
- If you have an allergy to Losiral or any other part of Losiral.
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you are pregnant or may be pregnant. Do not take Losiral if you are pregnant.
- If you are breast-feeding. Do not breast-feed while you take Losiral and for 3 weeks after your last dose.
This is not a list of all drugs or health problems that interact with Losiral.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Losiral with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
The extended adjuvant treatment trial (MA-17) was unblinded early . At the updated (final analysis), overall the side effects seen were consistent to those seen at a median treatment duration of 24 months.
During treatment or within 30 days of stopping treatment (median duration of treatment 60 months) a higher rate of fractures was observed for Femara (10.4%) compared to placebo (5.8%), as also a higher rate of osteoporosis (Femara 12.2% vs placebo 6.4%).
Based on 62 months median duration of follow-up in the randomized Losiral arm in the safety population the incidence of new fractures at any time after randomization was 13.3% for Losiral and 7.8% for placebo. The incidence of new osteoporosis was 14.5% for Losiral and 7.8% for placebo.
During treatment or within 30 days of stopping treatment (median duration of treatment 60 months), the incidence of cardiovascular events was 9.8% for Femara and 7.0% for placebo.
Based on 62 months median duration of follow-up in the randomized Losiral arm in the safety population the incidence of cardiovascular disease at any time after randomization was 14.4% for Losiral and 9.8% for placebo.
In the extended adjuvant setting (MA-17), based on a median duration of follow-up of 62 months, there was no significant difference between Femara and placebo in total cholesterol or in any lipid fraction over 5 years. Use of lipid lowering drugs or dietary management of elevated lipids was allowed .
How Losiral works
Losiral lowers the levels of the female sex hormone oestrogen in the body. Oestrogen stimulates some breast cancers to grow. These breast cancers are called hormone sensitive or hormone receptor positive. Losiral can stop or slow the growth of these cancers.
Losiral only works in women who have had their menopause.
After the menopause, women don't produce oestrogen from their ovaries. But they still produce a small amount by using an enzyme called aromatase which turns other sex hormones called androgens into oestrogen. This change happens mainly in fatty tissue, muscle and the skin. Losiral is a type of drug called an aromatase inhibitor. It blocks aromatase so that it can't change androgens into oestrogen.
Buy Losiral Online - Warning:
Countless people buy Losiral online every single day though anabolic steroid suppliers and RCL’s. However, if you buy Losiral from a steroid supplier, which will be in its original tablet form, in the U.S. you will be breaking the law. As for RCL’s, while a purchase is legal due to a loophole in the law, there are risks you need to be aware of. When you buy Losiral online from an RCL there is the risk of purchasing an inferior product. Low dosing is possible, but the most common problem is an unstable product. Further, if law enforcement wanted to make this an issue, it would be up to you to prove this purchase was made for research. If you have anabolic steroids in your possession this will be a hard sell to make. The best way to buy Losiral considering quality and legality will always be through the pharmacy based on the prescription given to you by your doctor. However, while possible a prescription is not as east to get as Arimidex.
Due to the laws that surround AI’s like Losiral and anabolic steroids, you are encouraged to visit the sponsors here at Steroid.com for you anabolic needs. The sponsors here at Steroid.com can provide you with high quality anabolics without a prescription and legally so. For those who suffer from low testosterone or who suspect it due to symptoms they may be showing, if you desire treatment and an AI like Losiral for part of your treatment you are strongly encouraged to visit Lowtestosterone.com. Lowtestosterone.com can guide you through the full low testosterone treatment plan and ensure you receive the treatment you need, the best products on the market and with 100% legal assurance.
Some side effects can be serious. If you experience any of these symptoms call your doctor immediately or get emergency medical treatment:
- chest pain
- difficulty breathing
- unusual bleeding or bruising
- pain in the upper right part of the stomach
- yellowing of the skin or eyes
- flu-like symptoms
- pain, warmth, or heaviness in the back of the lower leg
- severe headache
- sudden speech problems
- sudden weakness or numbness of an arm or leg
Losiral may cause or worsen osteoporosis. It can decrease the density of your bones and increase the chance of broken bones and fractures. Talk to your doctor about the risks of taking this medication.
Losiral may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).
Losiral may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- hot flushes
- night sweats
- loss of appetite
- stomach pain
- changes in weight
- muscle, joint, or bone pain
- excessive tiredness
- swelling of the hands, feet, ankles, or lower legs
- difficulty falling asleep or staying asleep
- vaginal bleeding or irritation
- breast pain
- hair loss
- blurry vision
What Is Losiral and How Does It Work?
Losiral is a prescription drug is used to treat certain types of breast cancer (such as hormone-receptor-positive breast cancer) in women after menopause. Losiral is also used to help prevent the cancer from returning. Some breast cancers are made to grow faster by a natural hormone called estrogen. Losiral decreases the amount of estrogen the body makes and helps to slow or reverse the growth of these breast cancers.
Losiral is available under the following different brand names: Femara.
Dosages of Losiral:
Adult Dosage Forms and Strengths
Dosage Considerations – Should be Given as Follows:
- 2.5 mg orally each day, until tumor progression evident
Other Indications and Uses
- Adjuvant treatment of postmenopausal, hormone receptor positive, early breast cancer
- Extended adjuvant treatment of early breast cancer in post-menopausal women after 5 years of adjuvant tamoxifen
- First and second-line treatment of postmenopausal women with hormone receptor positive or unknown advanced breast cancer
- Off-label: ovulation induction
- Safety and efficacy not established
Losiral comes in tablets of 2.5 milligrams (mg).
How much Losiral your doctor tells you to take may vary, but for cancer, a usual dose is 2.5 mg a day.
If you're taking Losiral for fertility treatment, your doctor may tell you to take either 2.5 mg or 5 mg of the drug, beginning on the third day of your period for five days.