Q: I stopped taking Prozac but continued with Wellbutrin. I am dizzy a lot since this change. Is it connected?
A: Prozac (Ladose) is an antidepressant which belongs to a class of medications called selective serotonin reuptake inhibitors (SSRIs). Prozac is used for the treatment of depression, obsessive-compulsive disorder (OCD), certain eating disorders, and panic attacks. Prozac helps treat depression by raising the amount of serotonin, a natural substance in the brain, that assists in maintaining mental balance. Prozac is usually taken once daily. Take Prozac at around the same time every day. Follow the directions on your prescription label carefully, and take Prozac exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Prozac usually takes about four to five weeks, or maybe longer, before you feel the full benefit of this drug. Continue to take Prozac even if you feel better. Do not stop taking Prozac without talking to your doctor first. If you suddenly stop taking Prozac, you may experience withdrawal symptoms such as mood changes, irritability, agitation, dizziness, numbness or tingling in the hands or feet, anxiety, confusion, headache, tiredness, and difficulty falling asleep or staying asleep. Since you are experiencing dizziness, it may be due to the withdrawal symptoms. You may have stopped taking your Prozac dose too abruptly. Consult with your doctor about lowering your dose more gradually. Then discuss other treatment options that would benefit your medical condition. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. Anissa Lee, RPh
Examples of Ladose in a Sentence
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Q: I am one of the slow reactors to the benefits of Prozac. And I do drink coffee - maybe 6 cups a day. Can it interfere with Prozac taking effect?
A: Prozac (Ladose) is in a class of drugs called selective serotonin reuptake inhibitors (SSRIs). Prozac is used to treat depression, obsessive-compulsive disorder, certain eating disorders, and panic attacks. Prozac works by increasing the amount of serotonin in the brain. Serotonin is a natural chemical that assists in maintaining mental balance.
Q: I'm currently taking Prozac. My depression seems to be getting worse. Could I double my daily dose?
A: Prozac (Ladose) is an antidepressant classified as a selective serotonin reuptake inhibitor (SSRI). Prozac is used to treat depression and anxiety. It can take approximately one month to see the full effects of this class of medications. However, there should be some improvement within the first few days of taking it. If you have been taking Prozac for a couple of weeks, and there is no improvement, you may want to ask your doctor to consider treatment with a different antidepressant. If there has been some improvement, your doctor may decide to increase the dose to 40 mg. The maximum dose of Prozac is 80 mg, but most people respond to the medication at lower doses. There are many affordable alternative SSRIs, including Zoloft (sertraline), Paxil (paroxetine), and Celexa (citalopram). They are all available in a generic form. Everyone responds differently to medications. With treatment with SSRIs, one medication may work well for one person, but not be optimal for someone else. It takes some time, but it is a matter of finding the right fit for your specific situation. Once you have been on an SSRI for an extended period of time, you should not stop taking it all of a sudden, as it can bring on extreme depression and anxiety. The medications should be tapered down when stopping, especially at high doses. If your doctor changes you to a different medication, there may be a cross-taper (coming down on one medication, while going up in dose on the new medication. There are also other types of antidepressants that can be used if treatment with an SSRI is not right for you. It is important to work with your doctor to find the right medication at the right dose for you. It is extremely important not to increase your current dose dose without the approval from your doctor. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. Patti Brown, PharmD
Q: How does bourbon interact with Prozac? Can it cause excessive bruising?
A: Prozac (Ladose) is in a class of drugs called selective serotonin reuptake inhibitors (SSRIs). Prozac is used to treat depression, obsessive-compulsive disorder, certain eating disorders, and panic attacks. Prozac works by increasing the amount of serotonin in the brain. Serotonin is a natural chemical that assists in maintaining mental balance. Generally speaking, drug interactions fall into three main categories: Drug-drug (i.e., prescription, over-the-counter, herbals, dietary supplements) interactions occur when two or more drugs react with each other. Drug-diet (food/drink) interactions result from drugs reacting with foods or drinks. Drug-disease interactions may occur when an existing medical condition makes certain drugs potentially harmful. No significant interactions between Prozac and bourbon (specifically) were identified; however, this does not necessarily mean no interactions exist. However, according to Prozac
Interactions that increase your risk of side effects
Increased side effects: Taking Ladose with certain medications raises your risk of side effects. This is because Ladose and these other medications can cause the same side effects. These drugs include serotonergic drugs, such as:
- selective serotonin reuptake inhibitors (SSRIs) such as Ladose and sertraline
- serotonin-norepinephrine reuptake inhibitors (SSNRIs) such as duloxetine and venlafaxine
- tricyclic antidepressants (TCAs) such as amitriptyline and clomipramine
- the opioids fentanyl and tramadol
- the anxiolytic buspirone
- St. John’s wort
Taking these drugs with Ladose may increase your risk of serotonin syndrome, which can be fatal. If you take any of these drugs, your doctor will start you on a lowered dosage of Ladose and monitor you for signs of serotonin syndrome. Symptoms can include agitation, sweating, muscle twitches, and confusion.
Increased side effects from other drugs: Taking Ladose with certain medications raises your risk of side effects from these drugs. Examples of these drugs include:
- Tryptophan. Taking these drugs together may cause you to have agitation, restlessness, and stomach problems.
- Benzodiazepines, such as triazolam and midazolam. Taking these drugs together may cause more sedation and drowsiness.
- Warfarin. Taking these drugs together may cause an increase in bleeding. Your doctor will monitor you closely.
- Nonsteroidal anti-inflammatory drugs (NSAIDs). Taking these drugs together may cause an increase in bleeding. Your doctor will monitor you closely.
- Aspirin. Taking these drugs together may cause an increase in bleeding. Your doctor will monitor you closely.
- Drugs broken down by the enzyme CYPD2D6, such as aripiprazole, dextromethorphan, methadone, paliperidone, and risperidone. Taking these drugs with Ladose may increase your risk of serotonin syndrome, heart rhythm problems, and involuntary muscle movements.
- Lithium. Your doctor should monitor your lithium blood levels if you need to take these drugs together.
- Phenytoin. Taking these drugs together may cause confusion, dizziness, and fever. You may also have changes in your behavior. These changes include anger, irritability, or sadness.
- Carbamazepine. Taking these drugs together can cause blurred vision, vertigo, or tremors.
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.
What is the dosage for Ladose?
Depression in adults is treated with 20-80 mg of Ladose daily. The recommended dose for treating depression in children is 10-20 mg daily. After 13 weeks of daily administration, 90 mg once weekly may be effective in some patients.
Use a starting dose of oral olanzapine 2.5 to 5 mg with Ladose 20 mg for patients with a predisposition to hypotensive reactions, patients with hepatic impairment, or patients who exhibit a combination of factors that may slow the metabolism of olanzapine or Ladose in combination (female gender, geriatric age, non-smoking status), or those patients who may be pharmacodynamically sensitive to olanzapine. Titrate slowly and adjust dosage as needed in patients who exhibit a combination of factors that may slow metabolism. PROZAC and olanzapine in combination have not been systematically studied in patients over 65 years of age or in patients less than 10 years of age .
Which drugs or supplements interact with Ladose?
Taking Ladose with other drugs that make you sleepy or slow your breathing can cause dangerous side effects or death. Ask your doctor before taking a sleeping pill, narcotic pain medicine, prescription cough medicine, a muscle relaxant, or medicine for anxiety, depression, or seizures.
Many drugs can interact with Ladose. Tell your doctor about all your current medicines and any you start or stop using, especially:
Taking monoamine oxidase inhibitors (MAOIs) with Ladose may cause a serious (possibly fatal) drug interaction. Avoid taking MAOIs (isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine) during treatment with Ladose. Most MAOIs should also not be taken for 2 weeks before and at least 5 weeks after treatment with Ladose. Ask your doctor when to start or stop taking this medication.
The risk of serotonin syndrome/toxicity increases if you are also taking other drugs that increase serotonin. Examples include street drugs such as MDMA/"ecstasy," St. John's wort, certain antidepressants (including other SSRIs such as citalopram/paroxetine, SNRIs such as duloxetine/venlafaxine), tryptophan, among others. The risk of serotonin syndrome/toxicity may be more likely when you start or increase the dose of these drugs.
Many drugs besides Ladose may affect the heart rhythm (QT prolongation), including pimozide and thioridazine, among others. Aspirin can increase the risk of bleeding when used with Ladose. However, if your doctor has directed you to take low-dose aspirin for heart attack or stroke prevention (usually at dosages of 81 to 325 milligrams a day), you should continue taking it unless your doctor instructs you otherwise.
Tell your doctor or pharmacist if you are taking other products that cause drowsiness including alcohol, antihistamines (such as cetirizine, diphenhydramine), drugs for sleep or anxiety (such as alprazolam, diazepam, zolpidem), muscle relaxants, and narcotic pain relievers (such as codeine).
Check the labels on all your medicines (such as allergy or cough-and-cold products), because they may contain ingredients that cause drowsiness. Ask your pharmacist about using those products safely.
Q: What is the recommended Prozac dosage?
A: The recommended Prozac (Ladose) dosage depends upon the indication for treatment. Prozac is a selective serotonin reuptake inhibitor (SSRI) antidepressant indicated for major depressive disorder, obsessive-compulsive disorder, bulimia and panic disorder, with or without agoraphobia. For the treatment of major depressive disorder in adults, the initial Prozac dosage is 20 mg per day administered in the morning. The usual recommended Prozac dosages range from 20 to 80 mg per day. According to clinical studies, 20 mg per day is typically an adequate Prozac dosage to achieve a satisfactory therapeutic response in most cases of major depressive disorder. Dosages greater than 20 mg per day may be administered once daily in the morning or twice daily (morning and noon) if necessary. Maximum daily doses should not exceed 80 mg per day. Prozac has also been proven effective for once weekly administration. For the treatment of major depressive disorder in the pediatric population, 8 years of age and older, the usual recommended Prozac dosage is 10 to 20 mg per day. Treatment with Prozac for major depressive disorder may require four weeks or longer before the full pharmacologic effect is observed. For the treatment of obsessive-compulsive disorder in adults, the initial Prozac dosage is 20 mg per day administered in the morning. The usual recommended Prozac dosages range from 20 to 60 mg per day. However, 80 mg per day dosages have been well tolerated in clinical studies. The maximum daily dose is 80 mg. For the treatment of obsessive-compulsive disorder in adolescents and higher weight children, 7 years of age and older, the usual recommended Prozac dosage is 20 to 60 mg per day with an initial dosage of 10 mg per day. For lower weight children, 20 to 30 mg per day is recommended. For the treatment of bulimia nervosa in adults, the usual recommended Prozac dosage is 60 mg per day administered in the morning. In some patients, dose titration over several days may be advisable. For the treatment of panic disorder in adults, the initial Prozac dosage is 10 mg per day. According to the prescribing information, the dosage should be increased to 20 mg daily after one week of treatment. The usual recommended Prozac dosage is 20 mg per day administered in the morning. During clinical trials, patients were administered dosages ranging from 10 to 60 mg. A dosage of 20 mg was most frequently administered to patients during clinical trials. For all indications of Prozac, it may require four weeks of treatment or longer before patients experience improvements in symptoms. It is essential for patients to continue with treatment exactly as directed to achieve desired therapeutic outcomes.
Q: I recently read that medications can cause bad dreams. I take a low dose of Prozac every other day to help with a mild case of anxiety. Since my Mom passed away five years ago, I have had many upsetting dreams about her being sick. She had a terrible fall and I watched her die in ICU in the hospital. She and I were very close and while I manage my grief well, I still regularly feel sad and upset about what happened to my Mom. Any idea that the medication could be contributing to the bad dreams? I never used to have disturbing dreams. Any recommendations on what I might do to stop or at least minimize these terrible dreams?
A: Prozac (Ladose) is a selective serotonin reuptake inhibitor agent prescribed for the treatment of depression, obsessive compulsive disorder, panic disorder and premenstrual dysphoric disorder. A search of the prescribing literature lists abnormal dreams as a common side effect and recommends that if this side effect becomes bothersome, medical intervention is recommended. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action.
What are the side effects of Ladose?
Ladose, as with most antidepressants, can cause nausea, headaches, anxiety, insomnia, drowsiness, and loss of appetite. Ladose has been implicated in serious skin rashes and vasculitis (inflammation of small blood vessels). Increased blood pressure can occur, and blood pressure should be monitored. Seizures have been reported as has sexual dysfunction. Some patients may experience withdrawal reactions upon stopping Ladose. Symptoms of withdrawal include anxiety, nausea, nervousness, and insomnia. The dose of Ladose should be gradually reduced when therapy is discontinued. Ladose and other antidepressants have been associated with angle closure attacks in people with narrow angle glaucoma.
Antidepressants increased the risk of suicidal thinking and behavior in short-term studies in children and adolescents with depression and other psychiatric disorders. Anyone considering the use of Ladose or any other antidepressant in a child or adolescent must balance this risk of suicide with the clinical need. Patients who are started on therapy should be closely observed for clinical worsening, suicidal thoughts, or unusual changes in behavior.
Princeton's WordNet (0.00 / 0 votes) Rate this definition:
Ladose, Ladose hydrocholor >(noun)
a selective-serotonin reuptake inhibitor commonly prescribed as an antidepressant (trade names Prozac or Sarafem); it is thought to work by increasing the activity of serotonin in the brain
Why it's used
Ladose oral capsule is used to treat the following conditions:
- Depression. This includes major depression, depressive episodes associated with bipolar I disorder, and treatment-resistant depression.
- Obsessive-compulsive disorder. This condition causes bothersome thoughts that won’t go away (obsessions) and the need to do certain actions over and over (compulsions).
- Bulimia nervosa. This condition is an eating disorder marked by binge eating followed by extreme behaviors to avoid gaining weight (purging, fasting, or excessive exercise).
- Panic attacks. These are sudden episodes of extreme fear and worry even though no threat exists.
- Mood-related symptoms of premenstrual dysphoric disorder. These symptoms include mood swings or episodes of excessive sadness, irritability, or anger.
1. About Ladose
Ladose is a type of antidepressant known as an SSRI (selective serotonin reuptake inhibitor).
It is often used to treat depression, and also sometimes obsessive compulsive disorder and bulimia.
Ladose helps many people recover from depression, and it has fewer unwanted effects than older antidepressants.
Ladose is available only on prescription. It comes as tablets and capsules.
What is Ladose?
Ladose is a selective serotonin reuptake inhibitor (SSRI) antidepressant. Ladose affects chemicals in the brain that may be unbalanced in people with depression, panic, anxiety, or obsessive-compulsive symptoms.
Ladose is used to treat major depressive disorder, bulimia nervosa (an eating disorder), obsessive-compulsive disorder, panic disorder, and premenstrual dysphoric disorder (PMDD).
Ladose is sometimes used together with another medication called olanzapine (Zyprexa) to treat manic depression caused by bipolar disorder. This combination is also used to treat depression after at least 2 other medications have been tried without successful treatment of symptoms.
If you also take olanzapine (Zyprexa), read the Zyprexa medication guide and all patient warnings and instructions provided with that medication.
What Is Prozac (Ladose)?
Prozac is the brand name of Ladose, a prescription drug used to treat depression.
This antidepressant is in a class of drugs known as selective serotonin reuptake inhibitors, or SSRIs. These medications work by increasing the amount of serotonin in the brain.
In addition to depression, Prozac is used to treat:
Ladose capsules and tablets sold under the brand name Sarafem are used to treat premenstrual dysphoric disorder (PMDD), a condition in which a woman has symptoms of depression, irritability, and tension before menstruation.
Prozac comes in several forms, including capsules, tablets, liquid, and delayed-release capsules.
Eli Lilly and Company makes Prozac, which was approved by the Food and Drug Administration (FDA) in 1987.
The delayed-release capsule Prozac Weekly is also made by Eli Lilly and Company.
Generic forms of Ladose, Ladose delayed-release capsules, and Sarafem are also available.
Do not stop taking Ladose suddenly, or without talking to your doctor first.
Ladose isn't any better or worse than other antidepressants.
However, sometimes people respond better to one antidepressant than to another. Talk to your doctor if you aren't feeling any better after 6 weeks.
Ladose does not affect any type of contraception including contraceptive pills or emergency contraception.
There's some evidence that Ladose can reduce the quality of sperm - but it's not known whether this reduces male fertility. The effect should reverse once you stop taking the medicine. Speak to your doctor if you're concerned.
For women, there's no firm evidence to suggest that taking Ladose will reduce your fertility. However, speak to a pharmacist or your doctor if you're trying to get pregnant. They may want to review your treatment.
The good effects of Ladose may, after a while, improve your sex life as your mood lifts and you become interested in life and relationships again.
Some of the possible negative effects include:
- men might get painful erections, problems with getting an erection and problems with ejaculating
- women might have some vaginal bleeding and might not reach orgasm the same way as before
- you may have a lower sex drive
Sexual side effects usually pass after the first couple of weeks. However, very rarely, they can be long lasting and may not get better even after stopping the medicine.
If these happen and are a problem for you, go back to your doctor to see if there's another treatment you can try.
Ladose can make you feel less hungry than usual, so you may lose weight when you start taking it.
If you start to have problems with your weight while taking Ladose, talk to your doctor or pharmacist.
Some people can't concentrate properly while they're taking Ladose. It might be best to stop driving and cycling for the first few days of treatment until you know how this medicine makes you feel.
You can drink alcohol while taking Ladose but it may make you feel sleepy. It might be best to stop drinking alcohol for the first few days of treatment until you see how the medicine affects you.
You can eat and drink normally while taking Ladose.
Antidepressants, including Ladose, are just one of several approaches to treating depression. Other potential treatments include:
- talking therapy (such as cognitive behavioural therapy)
- exercise programmes
- help to get a good night's sleep
Choosing a treatment that's most suitable for you depends on:
- how long you've had depression
- your symptoms
- whether you've had any previous periods of depression
- whether previous treatment has worked
- how likely you are to stick with your treatment
- the potential side effects
- your preferences and priorities
Cannabis with Ladose can give you a fast heartbeat. Cannabis can also make drowsiness worse with Ladose, especially in people who have just started taking it.
Methadone can increase the risk of side effects in people taking Ladose. It can be potentially dangerous to take Ladose with:
- stimulants like ecstasy (MDMA) or cocaine
- hallucinogens like LSD
- novel psychoactive substances (which used to be known as legal highs) like mephedrone