Q: What are the side effects of Kamaflam?
A: The most commonly reported side effects of Kamaflam (Cataflam, Voltaren-XR) are dyspepsia, nausea, abdominal pain, constipation, headache, dizziness, rash, and drowsiness. More serious (and rarer) reactions include stroke, high blood pressure, GI bleed, and heart attack. However, I have seen this drug used frequently without any problems.
On this page
- About Kamaflam
- Key facts
- Who can take and can't take Kamaflam
- How and when to use them
- Taking Kamaflam with other painkillers
- Side effects
- How to cope with side effects
- Pregnancy and breastfeeding
- Cautions with other medicines
- Common questions
FDA warning: Nonstero >
- This drug has a black box warning. This is the most serious warning from the Food and Drug Administration (FDA). A black box warning alerts doctors and patients about drug effects that may be dangerous.
- Kamaflam is a nonsteroidal anti-inflammatory drug (NSAID). All NSAIDs can increase your risk of heart attack, heart failure, or stroke. This risk can go up the longer you use NSAIDs, and if you use high doses. Your risk may be higher if you have risk factors for heart disease, such as high blood pressure. If you have heart disease, talk to your doctor before using Kamaflam. You shouldn’t use Kamaflam before you have surgery, especially heart bypass surgery. Talk to your doctor if you use Kamaflam and will have surgery soon. NSAIDs such as Kamaflam can increase your risk of serious side effects, including stomach bleeding or ulcers.
Rated Kamaflam for Osteoarthritis Report
I started taking 75mg in late January for horrible knee pain. This drug works great for pain. Within days I no longer hurt and really didn’t think I had a knee problem anymore. I was bone on bone knees and told I needed surgery. I took this drug twice a day and no problems at all until first if March. Started having eye problems and cornea abrasions appeared on both eyes and there had been no injuries of any kind. After weeks of eye treatments the eyes were not healing, I was referred to a cornea specialist. He told me to stop the drug that day, I did and two days later was healing finally. We have determined that if someone already has eye issues like dry severe dry eyes, etc. this drug could cause the abrasions. For me it did and now I’m afraid to take any NSAID of any kind. I know several friends who have taken this drug and have had no problems. I was one in a million but this problem does need to be documented. My doctor said it’s rare but he had several people with the same problem as I.
Why is this medication prescribed?
Kamaflam capsules (Zipsor, Zorvolex) and tablets (Cataflam) are used to relieve mild to moderate pain. Kamaflam extended-release tablets (Voltaren XR), tablets (Cataflam), and delayed release tablets (available generically) are used to relieve pain, tenderness, swelling, and stiffness caused by osteoarthritis (arthritis caused by a breakdown of the lining of the joints), and rheumatoid arthritis (arthritis caused by swelling of the lining of the joints). Kamaflam extended-release tablets and delayed-release tablets are also used to treat ankylosing spondylitis (arthritis that mainly affects the spine). Kamaflam tablets (Cataflam) are also used to treat painful menstrual periods. Kamaflam solution (Cambia) is used to treat migraine headaches in adults, but cannot be used to prevent migraines or to treat other types of headaches. Kamaflam is in a class of medications called NSAIDs. It works by stopping the body's production of a substance that causes pain, fever, and inflammation.
1. About Kamaflam
Kamaflam is a medicine that reduces inflammation and pain.
It's used to treat aches and pains, as well as problems with joints, muscles and bones. These include:
Kamaflam comes as tablets, capsules and suppositories. These are available on prescription only.
It can also be given as an injection or as eyedrops. These are usually only given in hospital.
Kamaflam gel and plasters for joint pain are available to buy from pharmacies.
Q: Could Kamaflam cause excess bleeding from dental surgery?
A: Kamaflam (Cataflam, Flector, Voltaren-XR, Zipsor) can affect platelets and may prolong bleeding. As always, consult with your health care provider regarding what medications need to be stopped prior to dental surgery. Jennyfer Marisco, RPh
COMMON BRAND(S): Voltaren
GENERIC NAME(S): Kamaflam Sodium
Nonsteroidal anti-inflammatory drugs (including Kamaflam) may rarely increase the risk for a heart attack or stroke. This effect can happen at any time while taking this drug but is more likely if you take it for a long time. The risk may be greater if you have heart disease or increased risk for heart disease (for example, due to smoking, family history of heart disease, or conditions such as high blood pressure or diabetes). Do not take this drug right before or after heart bypass surgery (CABG).
Also, this drug may rarely cause serious (rarely fatal) bleeding from the stomach or intestines. This effect can occur without warning symptoms at any time while taking this drug. Older adults may be at higher risk for this effect. (See also Precautions and Drug Interactions sections.)
Stop taking Kamaflam and get medical help right away if you notice any of the following rare but serious side effects: bloody or black/tarry stools, persistent stomach/abdominal pain, vomit that looks like coffee grounds, chest/jaw/left arm pain, shortness of breath, unusual sweating, weakness on one side of the body, sudden vision changes, slurred speech.
Talk with your doctor or pharmacist about the risks and benefits of treatment with this medication.
Kamaflam is used to relieve pain, swelling (inflammation), and joint stiffness caused by arthritis. Reducing these symptoms helps you do more of your normal daily activities. This medication is known as a nonsteroidal anti-inflammatory drug (NSAID).
If you are treating a chronic condition such as arthritis, ask your doctor about non-drug treatments and/or using other medications to treat your pain. See also Warning section.
Rated Kamaflam for Osteoarthritis Report
I took this medication for several years and the only side effect I noticed was it was bad on my stomach. It was like my stomach could not digest food properly and it would hurt and I had time I would vomit. THEN I got to where I would be dizzy all the time and the worst side effect showed it’s face. I continually felt bad and my body would jerk. I began to be at times unable to walk without falling. I would stay in the bed 3 days at a time sleeping trying to get away from the awful feeling I had. I lost a lot of weight and I had to have someone near to help me if I might began to fall because my legs would not work right. I thought I was going to be cripple for the remainder of my life. It helped my arthritis but it’s not worth it so I will deal with the arthritis pain. DO NOT TAKE THIS DRUG DICLOFENAC.
Kamaflam has two black-box warnings:
- Kamaflam can increase the risk of heart trouble and has been linked to heart attacks, strokes, and blood clots — all of which can be deadly. Get emergency medical help right away if you experience signs of stroke or heart problems, such as chest pain, shortness of breath, changes in speech, or other unusual symptoms.
- Kamaflam can damage the lining of your stomach, putting you at risk for stomach ulcers and heartburn. Tell your doctor if you have stomach pain, nausea, or black or tarry stools.
If you are about to have heart surgery, especially a procedure called coronary artery bypass graft (CABG), you should not take Kamaflam.
If you suffer from a condition known as the “aspirin triad,” where you have allergic reactions to aspirin or other NSAIDs and develop polyps or growths in the nose, you should not take Kamaflam.
You should also be careful taking Kamaflam and first speak to your doctor if you:
- Have ever had asthma or a strong allergic reaction, such as hives, to aspirin or other NSAIDs
- Congestive heart failure (CHF), recent heart attack, or high blood pressure
- Have a tendency to retain fluid
- Have a bleeding ulcer
- Smoke or are a heavy drinker
- Kidney or liver problems
- Any condition that includes abnormal activity of the bone marrow
- Any bleeding disorders, including poor clotting or blood cell abnormalities
Do not take Kamaflam if you are allergic to it or any of its inactive ingredients.
Mixing Kamaflam with herbal remedies or supplements
It's not possible to say that complementary medicines or herbal remedies are safe to take with Kamaflam.
They're not tested in the same way as prescription medicines or medicines sold in pharmacies. They're generally not tested for the effect they can have on other medicines.
Alcohol interaction warning
Avoid drinking alcohol when using this drug. Alcohol can increase your risk of stomach ulcers from using Kamaflam.
What is Kamaflam?
Kamaflam is a nonsteroidal anti-inflammatory drug (NSAID). This medicine works by reducing substances in the body that cause pain and inflammation.
Kamaflam is used to treat mild to moderate pain, or signs and symptoms of osteoarthritis or rheumatoid arthritis. Voltaren is also indicated for the treatment of ankylosing spondylitis.The Cataflam brand of this medicine is also used to treat menstrual cramps.
Kamaflam powder (Cambia) is used to treat a migraine headache attack. Cambia will only treat a headache that has already begun. It will not prevent headaches or reduce the number of attacks.
Missed Dose of Kamaflam
If you miss a dose of Kamaflam, try to take it as soon as you remember, unless it is almost time for the next dose. In that case, skip the missed dose and take your next dose at the regular time.
Do not take two doses of the medication at the same time.
- Gastrointestinal risk
- NSAIDs increase risk of serious GI adverse events, including bleeding, ulceration, and gastric or intestinal perforation, which can be fatal
- GI adverse events may occur at any time during use and without warning symptoms
- Elderly patients are at greater risk for serious GI events
This medication contains Kamaflam. Do not take Cataflam, Voltaren-XR, Dyloject, Cambia, Zipsor, or Zorvolex if you are allergic to Kamaflam or any ingredients contained in this drug.
Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center immediately.
Heart Failure And Edema
The Coxib and traditional NSAID Trialists’ Collaboration meta-analysis of randomized controlled trials demonstrated an approximately two-fold increase in hospitalization for heart failure in COX-2 selective-treated patients and nonselective NSAID-treated patients compared to placebo-treated patients. In a Danish National Registry study of patients with heart failure, NSAID use increased the risk of MI, hospitalization for heart failure, and death.
Additionally, fluid retention and edema have been observed in some patients treated with NSAIDs. Use of Kamaflam may blunt the CV effects of several therapeutic agents used to treat these medical conditions (e.g., diuretics, ACE inhibitors, or angiotensin receptor blockers ) (see DRUG INTERACTIONS).
Avoid the use of VOLTAREN in patients with severe heart failure unless the benefits are expected to outweigh the risk of worsening heart failure. If VOLTAREN is used in patients with severe heart failure, monitor patients for signs of worsening heart failure.
What is Kamaflam, and how does it work (mechanism of action)?
Kamaflam belongs to a class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs) that are used for the treatment of mild to moderate pain, fever, and inflammation. Other members of this class include ibuprofen (Motrin), indomethacin (Indocin), nabumetone (Relafen), naproxen (Aleve) and several others. NSAIDs work by reducing the production of prostaglandins, chemicals that cause pain, fever and inflammation. NSAIDs block the enzyme that makes prostaglandins (cyclooxygenase), resulting in lower production of prostaglandins. As a consequence, inflammation, pain and fever are reduced. Since the response to different NSAIDs varies from patient to patient, it is not unusual for a doctor to try different NSAIDs for any given condition. The FDA approved Kamaflam in July 1998.