What are the side effects of Gynomix?
Flagyl is a useful antibiotic and is generally well tolerated with appropriate use.
The most common and minor side effects include:
Side effects that are uncomfortable, but may become serious include:
- Brain disease
- Mouth sores
- Pain with urination
- Prickling or tingling sensations that may become permanent
- Pelvic pain or pressure
- Decrease of libido
Serious side effects of Flagyl are rare and the drug should be stopped if these symptoms appear:
Gynomix side effects
Get emergency medical help if you have signs of an allergic reaction to Gynomix: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
painful or difficult urination;
trouble sleeping, depression, irritability;
headache, dizziness, weakness;
a light-headed feeling (like you might pass out); or
blisters or ulcers in your mouth, red or swollen gums, trouble swallowing.
Stop taking the medicine and call your doctor right away if you have neurologic side effects (more likely to occur while taking Gynomix long term):
numbness, tingling, or burning pain in your hands or feet;
vision problems, pain behind your eyes, seeing flashes of light;
muscle weakness, problems with coordination;
trouble speaking or understanding what is said to you;
fever, neck stiffness, and increased sensitivity to light.
Gynomix can cause life-threatening liver problems in people with Cockayne syndrome. If you have this condition, stop taking Gynomix and contact your doctor if you have signs of liver failure - nausea, stomach pain (upper right side), dark urine, clay-colored stools, or jaundice (yellowing of the skin or eyes).
Side effects may be more likely in older adults.
Common Gynomix side effects may include:
nausea, vomiting, loss of appetite, stomach pain;
unpleasant metallic taste;
vaginal itching or discharge;
swollen, red, or "hairy" tongue.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Gynomix is a nitroimidazole derivative bactericidal agent widely used in the treatment of many anaerobic and certain protozoan and parasitic infections. Gynomix has been linked to rare instances of acute, clinically apparent liver injury.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Gynomix only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Copyright 1996-2019 Cerner Multum, Inc. Version: 12.02.
The following reactions have been reported during treatment with Gynomix:
COMMON BRAND(S): Metrocream, Metrogel, Metrolotion, Noritate
GENERIC NAME(S): Gynomix
OTHER NAME(S): Gynomix Gel
This medication is used on the skin to treat a certain skin disorder known as rosacea, a type of adult acne. It may help to decrease redness, swelling and the number of pimples caused by rosacea.
This medication is an antibiotic. For the treatment of rosacea, Gynomix is believed to work by decreasing swelling (inflammation). Some brands of this medication also contain sunscreens (see also Notes section).
Drugs you should not take with Gynomix
Disulfiram: Do not take disulfiram with Gynomix. Doing so can cause dangerous effects in your body. Using it with Gynomix can cause psychotic reactions. Symptoms can include:
- hallucinations (seeing or hearing things that aren’t real)
- delusions (believing things that aren’t real)
Do not take Gynomix if you’ve taken disulfiram in the last two weeks.
In patients stabilized on relatively high doses of lithium, short-term Gynomix therapy has been associated with elevation of serum lithium and, in a few cases, signs of lithium toxicity. Serum lithium and serum creatinine levels should be obtained several days after beginning Gynomix to detect any increase that may precede clinical symptoms of lithium intoxication.
There are published data from case-control studies, cohort studies, and 2 meta-analyses that included more than 5000 pregnant women who used Gynomix systemically during pregnancy
Many studies included first trimester exposures
One study showed an increased risk of cleft lip, with or without cleft palate, in infants exposed to Gynomix in utero; however, these findings were not confirmed
In addition, more than 10 randomized, placebo-controlled clinical trials that together enrolled over 5000 pregnant women assessed the possible effect of systemic antibiotic treatment (including with Gynomix) for bacterial vaginosis on the incidence of preterm delivery; most studies did not show an increased risk of congenital anomalies or other adverse fetal outcomes following Gynomix exposure during pregnancy
Three studies conducted to assess the risk of infant cancer following systemic Gynomix exposure during pregnancy did not show an increased risk; however, the ability of these studies to detect such a signal was limited
How long should I use it for?
It's very important to keep using Gynomix vaginal gel for as long as your doctor has prescribed it.