You should not use Fortagyl if you are allergic to it, or if you have taken disulfiram (Antabuse) within the past 2 weeks.
Do not drink alcohol or consume foods or medicines that contain propylene glycol while you are taking Fortagyl and for at least 1 day after you stop taking it. You may have unpleasant side effects such as fast heartbeats, warmth or redness under your skin, tingly feeling, nausea, and vomiting.
Seizures and other nervous system abnormalities have been reported in patients treated with Fortagyl. You should stop Fortagyl immediately for any neurological symptoms such as seizures, headaches, visual changes, weakness, numbness, or tingling.
This medicine will not treat a viral infection such as the common cold or flu.
In animal studies (mice and rats), this medicine caused certain types of cancers or tumors. It is not known whether these effects would occur in people using this medicine. Ask your doctor about your risk.
Metron >About Fortagyl
Mixing Fortagyl with herbal remedies and supplements
There are no known problems with taking herbal remedies and supplements alongside Fortagyl. However, some remedies and supplements that come as liquids that you drink may also contain alcohol. Check the list of ingredients or ask the supplier or manufacturer.
What other information should I know?
Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your response to Fortagyl.
Before having any laboratory test, tell your doctor and the laboratory personnel that you are taking Fortagyl.
Do not let anyone else take your medication. Your prescription is probably not refillable. If you still have symptoms of infection after you finish the Fortagyl, call your doctor.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
6. Vaginal gel
For treating bacterial vaginosis, you'll use an applicator to put the Fortagyl gel into your vagina. The usual dose is 1 applicator full, every night for 5 nights. It's recommended that you do not use the gel while having your period.
More common side effects
The most common side effects that can occur while taking Fortagyl tablets or capsules include:
- loss of appetite
- cramps in your abdomen
- metallic taste in your mouth
- yeast infection
- vaginal discharge
Seizures and aseptic meningitis reported with increase in dose and chronic therapy
Cases of encephalopathy and peripheral neuropathy (including optic neuropathy) reported with Fortagyl
Encephalopathy reported in association with cerebellar toxicity characterized by ataxia, dizziness, and dysarthria; CNS lesions seen on MRI described in reports of encephalopathy; CNS symptoms are generally reversible within days to weeks upon discontinuation of therapy; lesions seen on MRI have also been described as reversible
Peripheral neuropathy, mainly of sensory type reported and characterized by numbness or paresthesia of an extremity
Prescribing Fortagyl tablets in absence of a proven or strongly suspected bacterial or parasitic infection or a prophylactic indication is unlikely to provide benefit to patient and increases risk of development of drug-resistant bacteria and parasites
Superinfection may occur with prolonged use
Severe hepatic impairment; administer lower doses with caution
Use with caution; potential accumulation in end stage renal disease; supplemental doses may be needed in patients receiving hemodialysis
Use with caution in history of heart failure, hepatic failure, H. pylori infection, renal impairment
Use with care in patients with evidence of or history of blood dyscrasia; agranulocytosis, leukopenia and neutropenia have been associated with Fortagyl administration; monitor complete blood count; monitor complete blood count (CBC) for leukopenia before, during, and after prolonged repeated therapy
Avoid alcohol while taking medication and for at least three days after discontinuation
Antiandrogen: May cause gynecomastia
Known or previously unrecognized candidiasis may present more prominent symptoms during therapy and requires treatment with a candicidal agent
Fortagyl injection, USP contains 790 mg of sodium per 100 mL; use care when administering injection to patients receiving a controlled sodium diet or corticosteroids or to patients predisposed to edema
Severe neurological disturbances, including encephalopathy, cerebellar symptoms, convulsive seizures, and aseptic meningitis, reported in patients treated with Fortagyl; advise patients to report neurologic symptoms that occur during Fortagyl administration; discontinue Fortagyl treatment if any abnormal neurologic symptoms occur such as ataxia, dizziness, confusion or any other CNS adverse reaction
Cases of severe hepatotoxicity/acute hepatic failure, including cases with a fatal outcome with very rapid onset after treatment initiation in patients with Cockayne syndrome reported with products containing Fortagyl for systemic use; in this population, Fortagyl should therefore be used after careful benefit-risk assessment and only if no alternative treatment available; obtain liver function tests prior to start of therapy, within first 2-3 days after initiation of therapy, frequently during therapy and after end of treatment; discontinue Fortagyl if elevation of liver function occurs, and monitor liver function tests until baseline values are reached; advise patients with Cockayne syndrome to stop taking Fortagyl immediately if they experience any symptoms of potential liver injury, such as abdominal pain, nausea, change in stool color or jaundice, and to contact their healthcare provider
When Fortagyl tablets are prescribed to treat a bacterial infection, patients should be told that the medication should be taken exactly as directed; skipping doses or not completing full course of therapy may decrease effectiveness of immediate treatment and increase likelihood that bacteria will develop resistance and will not be treatable by Fortagyl tablets in the future
2. Key facts
- The most common side effects of Fortagyl tablets, liquid, suppositories or vaginal gel are feeling or being sick, diarrhoea, and a slight metallic taste in your mouth.
- Do not drink alcohol while taking a course of Fortagyl tablets, liquid, suppositories or vaginal gel, or for 2 days after finishing treatment. Alcohol can cause side effects such as feeling and being sick, stomach pain, hot flushes, a pounding heartbeat (palpitations) and a headache.
- For most infections, you'll start to feel better in a few days but for some it may take longer. When treating rosacea, you may only notice a difference after several weeks.
- Fortagyl tablets or suppositories are called by the brand name Flagyl.
- Fortagyl cream is called by the brand names Rosiced or Rozex. The gel is called by the brand names Acea, Anabact, Metrogel, Metrosa, Rozex or Zyomet.
What if I use too much?
If you accidentally use too much gel it's unlikely to harm you.
Talk to your pharmacist or doctor if you're worried.
It's unusual to have side effects when using Fortagyl cream or gel. However there can be some common side effects with the tablets, suppositories or vaginal gel.
Do not drink alcohol while taking the tablets or liquid or using the vaginal gel or suppositories. It can give you severe side effects such as feeling or being sick, stomach pain, hot flushes, a pounding heartbeat (palpitations) and a headache. After finishing your treatment, wait for 2 days before drinking alcohol again. This allows the Fortagyl to leave your body.
Do not share this medication with others.
This medication has been prescribed for your current condition only. Do not use it later for another condition unless told to do so by your doctor. A different medication may be necessary in those cases.
Sun exposure can worsen rosacea. Limit exposure to the sun by wearing a wide-brimmed hat and using a sunscreen that is SPF 15 or greater. If your brand already contains a sunscreen, you should use a regular sunscreen (without the Fortagyl) on areas of skin not treated with this medication.
Avoid certain triggers that may worsen rosacea such as wind, hot beverages, spicy foods, alcohol, and extreme cold. Discuss with your doctor.