How much to take
The usual dose of Fluxetin is 20mg a day in adults. However, you may be started at a lower dose which is gradually increased to a maximum dose of 60mg a day. Some people might need to take a lower dose of Fluxetin, or to take it less often. This includes people with liver problems, and elderly people.
The usual dose of Fluxetin in children is 10mg a day but this may be increased to 20mg a day.
Use a starting dose of oral olanzapine 2.5 to 5 mg with Fluxetin 20 mg for patients with a predisposition to hypotensive reactions, patients with hepatic impairment, or patients who exhibit a combination of factors that may slow the metabolism of olanzapine or Fluxetin in combination (female gender, geriatric age, non-smoking status), or those patients who may be pharmacodynamically sensitive to olanzapine. Titrate slowly and adjust dosage as needed in patients who exhibit a combination of factors that may slow metabolism. PROZAC and olanzapine in combination have not been systematically studied in patients over 65 years of age or in patients less than 10 years of age .
Q: How long does it take for Prozac to get out of the body?
A: Prozac (Fluxetin) //www.everydayhealth.com/drugs/prozac has a slow elimination. The rate of elimination depends on various factors including how long a patient has been on the medication, individual patient metabolism, etc. Prozac is broken down in the body to an active metabolite called norFluxetin. NorFluxetin can have a half life of 4-16 days depending on length of therapy of the medication. The half life is the amount of time it takes for one half of the drug to be eliminated from the body. This long half life can cause active drug substance to still be in the body for weeks after dosing is stopped. Jennyfer Marisco, RPh
Q: What condition is Prozac used for? Is it used in weight reduction? Is it safe? What are the side effects?
A: Prozac (Fluxetin) is a medication that is used to treat depression, panic disorder, obsessive compulsive disorder (OCD), depression associated with bipolar disorder, as well as other conditions. It is in the class of medications called selective serotonin reuptake inhibitors (SSRIs) and works by bringing a balance to serotonin in the brain that may be the cause of symptoms. The prescribing information on Prozac lists the following as the most common side effects associated with the medication: insomnia, nausea, diarrhea, headache, loss of appetite, drowsiness, anxiety, tremor, dry mouth, decreased sex drive, yawning, indigestion, dizziness and sweating. Prozac is not approved by the U.S. Food and Drug Administration (FDA) for weight loss. Weight loss appears to be a side effect that occurs in up to 2 percent of patients taking Prozac. It is not entirely clear why this medication causes weight loss, although it is generally a small amount. It may be due to the side effects of loss of appetite, diarrhea and nausea that may contribute to the weight loss. Lori Poulin, PharmD
More common side effects
The more common side effects of Fluxetin can include:
- strange dreams
- decreased sex drive and trouble having an orgasm
- decreased appetite
- anxiety and nervousness
- dry mouth
- erectile dysfunction (trouble getting or keeping an erection)
- trouble sleeping
- sore throat
- watery nasal discharge
- sweating and hot flashes
- tremors (uncontrollable rhythmic movement in one part of your body)
If these effects are mild, they may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, talk to your doctor or pharmacist.
4. How and when to take it
Take Fluxetin once a day. It doesn't upset your stomach so you can take it with or without food.
You can take Fluxetin at any time, as long as you stick to the same time every day. If you have trouble sleeping, it's best to take it in the morning.
Q: Does Prozac cause weight gain?
A: Drugs can cause weight gain in several different ways. Some can increase appetite or make you crave certain types of foods like those high in carbohydrates or fat. Other medications may slow down metabolism or cause fluid retention. However, the effect of prescription drugs on body weight is complex. Some drugs have no effect on weight, while others cause weight gain or weight loss. Also, the same medications can cause weight gain in certain individuals and weight loss in others. There are also drugs that initially cause weight loss and then lead to weight gain with long-term use. Most prescription medications associated with changes in body weight affect the central nervous system. These include antidepressants like monoamine oxidase inhibitors (MAOIs), tricyclic antidepressants, and selective serotonin reuptake inhibitors (SSRIs). Mood stabilizers (lithium, valproic acid), antipsychotics, and anticonvulsants have also been linked with weight gain. Prozac (Fluxetin) is an SSRI which may lead to weight gain or loss. Other drugs that have been reported to cause weight gain include diabetes medications (insulin, sulfonylureas, and thiazolidinediones), antihypertensive drugs, certain hormonal contraceptives, corticosteroids, antihistamines, some chemotherapy regimens, and antiretroviral protease inhibitors. If you think a drug you are taking is causing weight gain, tell your health care provider. Do not stop any medication or change the dose without first talking to your provider. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. Laura Cable, PharmD., BCPS