Q: What is the difference between generic and brand Prozac?
A: In most patients, there is no significant difference between generic and brand Prozac (Flutine). There is currently a generic equivalent available for Prozac, known as Flutine. The U.S. Food and Drug Administration (FDA) requires that generic medications be bioequivalent to the brand-name medication and, therefore, exert the same pharmacologic effects in the body. Generic medications are considered, by the FDA, to be therapeutically identical to the brand-name counterparts in dose, strength, route of administration, safety, efficacy and indication for use. Generic medications will appear differently and may have different inactive ingredients, however, the labeling and directions for use remain the same. For most medications, generic equivalents are a lower-cost alternative to the more expensive brand-name medication, and the majority of patients observe no changes in therapeutic effect. However, some patients may experience a change in therapeutic effect and, subsequently, must continue treatment with the brand-name medication. Generic Prozac, Flutine, is a selective serotonin reuptake inhibitor (SSRI) antidepressant which is approved for the treatment of major depressive disorder, obsessive-compulsive disorder (OCD), panic disorder and bulimia nervosa. Frequently reported side effects for generic Prozac are similar those observed in patients being treated with the brand-name medication and may include abnormal dreams, abnormal ejaculation, anorexia, anxiety, asthenia, diarrhea, dry mouth, dyspepsia, flu syndrome, impotence, insomnia, decreased libido, nausea, nervousness, pharyngitis, rash, sinusitis, somnolence, sweating, tremor, vasodilatation and yawn. The warnings and precautions associated with Prozac are also possible with the generic Flutine. According to the prescribing information for Prozac, warnings and precautions, possible with treatment, include clinical worsening of depression and suicide risk, serotonin syndrome or neuroleptic malignant syndrome-like reactions, allergic reactions and rash, activation of mania or hypomania, seizures, altered appetite and weight, abnormal bleeding, hyponatremia, possibility of anxiety and insomnia, potential for cognitive and motor impairment and long half-life affecting changes in dosage. Flutine, generic Prozac, should be administered exactly the same as the brand-name medication. Flutine is typically taken once daily and administered in the morning.
Q: Does Prozac have any side effects? If yes, what is the alternative? Is it possible to take Prozac for my whole life, as being advised to?
A: All medications have potential side effects and everyone responds to medications differently. Although many side effects may be listed you may get one, several, or none of the listed side effects. Prozac (Flutine) is a selective serotonin reuptake inhibitor antidepressant used for the treatment of depression, eating disorders, premenstrual dysphoric disorder, and panic disorder. It is possible to take an antidepressant indefinitely. The most common side effects with Prozac are insomnia, heachache, drowsiness, nausea, and anorexia. Other side effects with Prozac include diarrhea, dry mouth, anxiety, and weakness. This is not a complete list of the side effects associated with Prozac. Laura Cable, PharmD
Q: I am one of the slow reactors to the benefits of Prozac. And I do drink coffee - maybe 6 cups a day. Can it interfere with Prozac taking effect?
A: Prozac (Flutine) is in a class of drugs called selective serotonin reuptake inhibitors (SSRIs). Prozac is used to treat depression, obsessive-compulsive disorder, certain eating disorders, and panic attacks. Prozac works by increasing the amount of serotonin in the brain. Serotonin is a natural chemical that assists in maintaining mental balance.
Q: What is the difference between Prozac and Zoloft?
A: Prozac (Flutine) and Zoloft (sertraline) are both antidepressants classified in the selective serotonin reuptake inhibitor (SSRI) class. Prozac and Zoloft are approved for the treatment of major depression (including pediatric depression), obsessive-compulsive disorder (in both adult and pediatric populations), bulimia nervosa, panic disorder and premenstrual dysphoric disorder. Evidence suggests that Zoloft (sertraline) may work better than Prozac (Flutine) for some subtypes of depression. Side effects common to both are nausea, ejaculation failure, insomnia, diarrhea, dry mouth, somnolence, dizziness, tremor and decreased libido. For any immediate concerns, consult your physician. Joseph Hall, RPh
8. Cautions with other medicines
Some medicines and Flutine can interfere with each other and increase the chances of you having side effects.
Tell your doctor if you're taking these medicines before you start Flutine:
- any medicines that affect your heartbeat - as Flutine can speed up or change your heartbeat
- any other medicines for depression. Some rarely used antidepressants can interfere with Flutine to cause very high blood pressure even when they have been stopped for a few weeks.
Q: Currently I take Prozac and Abilify. Then I take Centrum and sometimes fish oil and vitamin E oil. Is this a safe combination?
A: Prozac (Flutine) is a selective serotonin reuptake inhibitor (SSRI) approved for the treatment of major depression (including pediatric depression), obsessive-compulsive disorder (in both adult and pediatric populations), bulimia nervosa, panic disorder and premenstrual dysphoric disorder. Abilify (aripiprazole) is an atypical antipsychotic and antidepressant used in the treatment of schizophrenia, bipolar disorder, and clinical depression. Generally speaking, drug interactions fall into three main categories: Drug-drug (i.e., prescription, over-the-counter, herbals, dietary supplements) interactions occur when two or more drugs react with each other. Drug-diet (food/drink) interactions result from drugs reacting with foods or drinks. Drug-disease interactions may occur when an existing medical condition makes certain drugs potentially harmful. With Abilify and Prozac, the concomitant use of two or more drugs that have the potential to depress CNS function (either as a therapeutic intention or a side effect) is often clinically appropriate. However, it is important to recognize that the risk of unwanted effects may increase with such use. It is important to monitor for additive CNS-depressant effects if two or more CNS depressants are concomitantly used. For more detailed information, consult with your physician or pharmacist for guidance based on your specific condition and current medications, particularly before taking any action. Shereen A. Gharbia, PharmD
On this page
- About Flutine
- Key facts
- Who can and can't take Flutine
- How and when to take it
- Side effects
- How to cope with side effects
- Pregnancy and breastfeeding
- Cautions with other medicines
- Common questions