Flanax tablets

Flanax

  • Active Ingredient: Naproxen
  • 500 mg, 250 mg
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What is Flanax?

The active ingredient of Flanax brand is naproxen. Naproxen is a nonsteroidal anti-inflammatory drug (NSAID). Naproxen works by reducing hormones that cause inflammation and pain in the body. C14H14O3 M.W. 230.26 Naproxen has a molecular weight of 230.26 and a molecular formula of C14H14O3. Naproxen USP is an odorless, white to off-white crystalline substance powder. It is lipid-soluble, practically insoluble in water, soluable in alcohol and in methanol at low pH and freely soluble in water at high pH. The octanol/water partition coefficient of Naproxen at pH 7.4 is 1.6 to 1.8. Naproxen Oral Suspension USP for oral administration contains 125 mg Naproxen USP per 5 mL and the following inactive ingredients: FD&C Yellow #6, fumaric acid, imitation orange flavor, imitation pineapple flavor, magnesium aluminum silicate, methylparaben, purified water, sodium chloride, sorbitol solution and sucrose. It has a sodium content of 39.3 mg/5 mL, 1.71 mEq/5 mL, with a pH range of 2.2 to 3.7.

Used for

Flanax is used to treat diseases such as: Ankylosing Spondylitis, Aseptic Necrosis, Back Pain, Bursitis, Chronic Myofascial Pain, Costochondritis, Diffuse Idiopathic Skeletal Hyperostosis, Dysautonomia, Fever, Frozen Shoulder, Gout, Acute, Headache, Juvenile Rheumatoid Arthritis, Muscle Pain, Neck Pain, Osteoarthritis, Pain, Period Pain, Radiculopathy, Rheumatoid Arthritis, Sciatica, Spondylolisthesis, Tendonitis, Transverse Myelitis.

Side Effect

Possible side effects of Flanax include: increased thirst; flushed, dry skin; red-green color blindness; cough or hoarseness; large, flat, blue, or purplish patches in the skin; hearing loss; muscle aching, cramping, stiffness, or weakness; chest pain or discomfort.

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Flanax sodium

Pharmacologic class: Nonsteroidal anti-inflammatory drug (NSAID)

Therapeutic class: Nonopioid analgesic, antipyretic, anti-inflammatory

Pregnancy risk category B (first and second trimesters) D (third trimester)

What is the dosage for Flanax?

The usual adult dose for pain is 250 every 6 to 8 hours or 500 mg twice daily using regular Flanax tablets. The usual dose for Naprelan controlled release tablets is 750 to 1000 mg given once daily. For EC-Naprosyn, the usual dose is 375-500 mg twice daily.

Flanax should be given with food to reduce upset stomach. The dose for rheumatoid arthritis, osteoarthritis, or ankylosing spondylitis is 500 to 1000 mg every 12 hours. Dysmenorrhea is treated with 250 mg every 6 to 8 hours after an initial dose of 500 mg.

High blood pressure warning

Flanax can cause high blood pressure or make your high blood pressure worse. It can also make your high blood pressure medications not work as well. You may need to watch your blood pressure level carefully while taking Flanax.

Brand Name: Aleve, EC Naprosyn, Anaprox, Anaprox DS, Naprosyn, Naprox Sodium, Flanax EC, Flanax SR, Naprelan, Menstridol

Q: I've been taking Flanax for about 5 weeks. My doctor wants to give me a lower dose and have me take it one day on and two days off. His concern is that it will burn out my stomach. I have not had any adverse abdominal problems to date. The lower dose does not relieve enough of the pain to be worth it to me. Is this the best approach? Is there a test to check if there is a problem developing?

A: Flanax (Naprosyn) is a non-steroidal anti-inflammatory drug (NSAID) that blocks substances in the body that normally cause pain and inflammation. Flanax is indicated for pain associated with headache, cramps, and other pain. Flanax is also used for pain and inflammation associated with arthritis and used as a fever reducer. Some of the common side effects associated with Flanax include constipation, diarrhea, headache, nausea, and stomach upset. According to the prescribing information, there are warnings associated with the use of Flanax. Long-term used of Flanax can increase the risk of serious cardiovascular events such as strokes and heart attacks. The risk of a serious adverse event can increase with the duration of treatment with Flanax. Flanax should not be used just before or after coronary artery surgery. People with cardiovascular risk factors, those who are 60 years of age or older, have stomach ulcers or bleeding problems, take blood thinners or drink alcoholic drinks while taking Flanax are at a greater risk of a complication. Flanax can increase the risk of serious stomach and intestine problems including bleeding or forming a hole (perforation). Talk to the doctor if signs and symptoms of bleeding occur. These symptoms include black, tarry or bloody stools or coughing up blood or vomit that looks like coffee grounds. Alcohol can increase the risk of stomach bleeding caused by Flanax. Avoid prolonged exposure to sunlight. Flanax can worsen existing hypertension (high blood pressure), so talk to your doctor if you have hypertension. The lowest dose and shortest duration of treatment with NSAIDs for effective therapy is usually recommended. However, talk to your doctor if Flanax is not relieving the pain. Do not stop taking Flanax or take more medicine than what is prescribed. For more specific information and guidance on your current treatment based on your medical condition, consult with your healthcare provider. Kimberly Hotz, PharmD

Serious side effects

Although people can buy low-dose Flanax without a prescription, it is not safe for everyone.

People with serious heart conditions, such as heart disease, cerebrovascular disease, and congestive heart failure, may experience severe side effects from taking Flanax.

Severe side effects of Flanax include:

People with high blood pressure should only take Flanax cautiously.

Flanax can cause sodium retention in the kidneys, which can result in increased blood pressure. A person with high blood pressure should consult their doctor before taking Flanax.

Gastrointestinal side effects of taking Flanax can be severe. Bleeding in the stomach, the formation of ulcers, and stomach or intestinal blockages can occur when taking Flanax. Most often, older adults are the most vulnerable age group for gastrointestinal side effects.

People who have a history of ulcers or gastrointestinal bleeding have a 10-fold higher risk for developing a bleed when taking Flanax. For these individuals, even short-term treatment can be risky.

Alcohol interaction warning

Combining Flanax and alcohol increases your risk of ulcer and stomach bleeding.

Dosage for osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis

Adult dosage (ages 18 years and older)

Flanax:

Immediate-release oral tablet

  • The typical dosage is 500 to 1,000 mg daily in two divided doses.
  • The maximum dose is 1,500 mg per day. This should be given for a limited time period (up to 6 months).

Delayed-release oral tablet

  • The typical dosage 375 to 500 mg twice daily.
  • The maximum dose is 1,500 mg per day. This should be given for a limited time period (up to 6 months).

Flanax sodium:

Immediate-release oral tablet

  • The typical dosage is 275 to 550 mg twice daily.
  • The maximum dose is 1,650 mg per day. This should be given for a limited time period (up to 6 months).

Extended-release oral tablet

  • The typical dosage is 750 or 1,000 mg once daily.
  • The maximum dose is 1,500 mg per day. This should be given for a limited time period.

Child dosage (ages 0–17 years)

A dosage for people younger than 18 years hasn’t been established.

Special dosage considerations

If you’re older than 65 years, your body may process this drug more slowly. Your doctor may start you on a lowered dose so that too much of this drug doesn’t build up in your body. Too much of the drug in your body can be dangerous.

How to take it

Flanax on prescription comes as 2 different tablets: effervescent and gastro-resistant tablets.

Effervescent tablets are dissolved in water before you take them.

Gastro-resistant tablets have a coating to protect them from being broken down by the acid in your stomach. Instead, the medicine is released further down the gut in your intestine.

If you take gastro-resistant tablets, swallow them whole with or after food. Do not crush or chew them.

If you take effervescent tablets, dissolve 1 to 2 tablets in a glass (150ml) of water and drink.

Doses of 3 tablets should be dissolved in 300ml. To make sure there's no medicine left, rinse the empty glass with a small amount of water and drink it. Take with or after food.

Q: Does Flanax cause anemia?

A: Flanax (Aleve, Naprosyn) belongs to a class of drugs called non-steroidal anti-inflammatory drugs (NSAIDs). NSAIDs work by blocking substances in the body that cause pain and inflammation. Flanax is used to treat fever, pain, and inflammation caused by a wide variety of conditions, including arthritis, bursitis, gout, headache, ankylosing spondylitis, tendonitis, menstrual cramps, and minor injuries. Common side effects of Flanax include nausea, stomach upset, heartburn, bloating, gas, diarrhea, constipation, dizziness, drowsiness, blurred vision, and ringing in the ears. A search of a drug database shows that anemia can occur in up to 10 percent of patients taking NSAIDs, including Flanax. This would be considered a frequent or common side effect. Consult with your doctor if you are concerned about anemia or if you are experiencing symptoms of anemia, such as fatigue, pale skin, coldness, or dizziness. This is not a complete list of risks or side effects that can occur with Flanax or any other NSAID. For more specific information, consult with your doctor or local pharmacist for guidance based on your health status and current medications, particularly before taking any action. Sarah Lewis, PharmD

Michael Stewart, Reviewed by Sid Dajani | Last edited 12 May 2017 | Certified by The Information Standard

Flanax is a medicine called a non-steroidal anti-inflammatory drug. It is also known as 'an NSAID'.

Before you take Flanax, let your doctor know if you have ever had a bad reaction to any other anti-inflammatory painkiller.

Make sure you take Flanax as directed on the label of the pack. Your dose will depend upon your condition and the brand of tablet prescribed.

Q: What health effects does Flanax have on the kidneys?

A: As long as you have good kidney function and no liver disease, you can use Flanax. Your doctor should monitor your kidney function as long as you are on Flanax, however. The literature cites effects such as glomerular nephritis, hematuria, interstitial nephritis, nephrotic syndrome, nephropathy, and tubular necrosis. Since your doctor knows your medical condition, discuss any concerns you have about Flanax with him or her. For more information about Flanax, go to //www.everydayhealth.com/drugs/Flanax. Gerald S. Levy, RPh


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