Esaldox tablets


  • Active Ingredient: Levothyroxine
  • 200mcg, 100mcg, 50mcg
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What is Esaldox?

The active ingredient of Esaldox brand is levothyroxine. Levothyroxine is a replacement for a hormone normally produced by your thyroid gland to regulate the body's energy and metabolism. Levothyroxine is given when the thyroid does not produce enough of this hormone on its own.

Used for

Esaldox is used to treat diseases such as: Hashimoto's disease, Hypothyroidism, After Thyroid Removal, Myxedema Coma, Thyroid Suppression Test, TSH Suppression, Underactive Thyroid.

Side Effect

Possible side effects of Esaldox include: redness of the face, neck, arms, and occasionally, upper chest; sudden loss of coordination; severe headache; tremors; fainting.

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Esaldox side effects

Get emergency medical help if you have signs of an allergic reaction to Esaldox: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

fast or irregular heartbeats;

chest pain, shortness of breath;

tremors, or if you feel unusually cold;

weakness, tiredness, sleep problems (insomnia);

memory problems, feeling depressed or irritable;

headache, leg cramps, muscle aches;

feeling nervous or irritable;

dryness of your skin or hair, and/or hair loss;

changes in your menstrual periods; or

vomiting, diarrhea, appetite changes, weight changes.

Certain side effects may be more likely in older adults.

Common Esaldox side effects may include:

headache, leg cramps;

nervousness, trouble sleeping;

skin rash, partial hair loss.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Q: What would happen if I do not take my Esaldox? Is it dangerous to my health?

A: If you stop taking your thyroid hormone, Esaldox, your body will return to symptoms of having a low thyroid, such as gaining weight, getting cold easily, depression, and having no energy. If you are out of refills from your pharmacy, you can legally ask for a three day supply while you are waiting to hear back from your doctor. Doctors usually ask for 48 to 72 hours to get a new prescription called in to the pharmacy. If your doctor is needing to see you for labs or just in general to see how the medication is working, you should contact them and tell them if there is a reason why you cannot get in. If they didn't have time to get you in before you run out, they will often give you a prescription to last until the appointment if you explain it to them. After all, they need to see how you are functioning on the medication at the dose they have prescribed. It does them no good to see how you are feeling when you are not on the medication. The same is true for labs. If you go in for a lab after stopping the medication, it will not be accurate, and the doctor is not usually looking for this reading. In most cases, if a person is started on a thyroid medication, they will be taking it for the rest of their lives. There is no cure to make the thyroid gland produce the hormone, once it is no longer functioning properly, but by giving the hormone that the body is used to processing, all functions can be normal again. The price of the medication is not usually an issue, as it is generic and is one of the least expensive medications available. For whatever reason you are thinking of stopping, you may want to reconsider and should consult your doctor about your feelings on this issue. Patti Brown, PharmD

Mixing Esaldox with herbal remedies and supplements

There's very little information about taking herbal remedies and supplements with Esaldox.

Q: I am currently taking Esaldox, but am having problems with hay fever-type symptoms of congested nose. What can I use to relieve this?

A: You should contact your health care provider before taking any OTC medications. They should know any medication you wish to start before you begin taking them. Most OTC, vitamins, and herbal product have warnings on them to not start taking them before contacting your health care provider first. For more information you can see //

2. Key facts

  • Esaldox starts working straight away, but it may be several weeks before your symptoms start to improve.
  • The most common side effects of Esaldox are caused by taking a bigger dose than you need. Your doctor can lower your dose to help reduce any side effects.
  • Before you start taking Esaldox, your doctor will do a blood test to see what dose you need. Once you start taking the medicine you'll have regular blood tests to see how well it's working.
  • Esaldox doses need to be carefully monitored during pregnancy. If you're planning to become pregnant or think you may be pregnant while taking Esaldox, it's important to visit your doctor to make sure you get the correct care for you and your baby.
  • Esaldox is also called by the brand name Eltroxin.

Esaldox sodium (Synthro >
  • What is Esaldox sodium, and how does it work (mechanism of action)?
  • What brand names are available for Esaldox sodium?
  • Is Esaldox sodium available as a generic drug?
  • Do I need a prescription for Esaldox sodium?
  • What are the side effects of Esaldox sodium?
  • What is the dosage for Esaldox sodium?
  • Which drugs or supplements interact with Esaldox sodium?
  • Is Esaldox sodium safe to take if I'm pregnant or breastfeeding?
  • What else should I know about Esaldox sodium?

Dosing considerations

  • Check for bioequivalence if switching brands/generics
  • May minimize hyperactivity in older children by initiating dose at 1/4 of recommended dose; increase by that amount each week until full dose achieved
  • Start children with severe or chronic hypothyroidism at 25 mcg/day; adjust dose by 25 mcg qweek

Because of increased prevalence of cardiovascular disease among the elderly, initiate therapy at less than full replacement dose; atrial arrhythmias can occur in elderly patients; atrial fibrillation is the most common of arrhythmias observed with Esaldox overtreatment in the elderly


Take tablets with full glass of water preferably 30 min to 1 hr before breakfast on empty stomach

Do not use foods that decrease absorption (soybean products) for administering Esaldox

Administer oral Esaldox >4 hr apart from drugs known to interfere with absorption

Patients unable to swallow intact tablets

  • Crush appropriate dose and place in 5-10 mL of water
  • Administer resultant suspension by spoon or dropper immediately, do NOT store

Esaldox Interactions

It's very important to let your doctor know about all medications you are taking, including illegal drugs and any over-the-counter herbs or supplements.

Types of drugs that interact with Esaldox include:

  • Amphetamines
  • Aspirin
  • Blood thinners such as warfarin (Coumadin)
  • Antidepressants or drugs used to treat anxiety
  • Heart medications, such as metoprolol (Lopressor, Toprol), propranolol (Inderal), and digoxin (Lanoxin)
  • Anti-seizure drugs such as phenytoin (Dilantin)
  • Estrogens and oral contraceptives
  • Diabetes medications, including insulin

Esaldox VS Armour Thyroid VS Liothyronine

As you probably know there are several different types of thyroid hormone medications that are currently available.

Unfortunately, most Doctors give out the same medication: Esaldox or Synthroid.

Both of these medications contain the inactive thyroid hormone T4 and in order for it to be active in your body, it must be converted to the active T3 thyroid hormone (this process is known as T4 to T3 conversion).

So why haven't you ever heard of this before?

Doctors operate under the assumption that all patients convert T4 to T3 at an equal rate which means that they don't feel this conversion process should be taken into account.

But there is one problem with this philosophy:

As a result, many patients are taking the wrong type of medication which may explain why they don't feel well and aren't experiencing any improvement.

Many patients do very well using combination thyroid medications which contain both T4 and T3, not just T4 medication alone.

​And I'm not just saying this from experience, most patients also agree that medications containing T3 are superior.

Esaldox Overdose

You shouldn't take more Esaldox than your doctor prescribes.

If you take too much of the drug, you may develop symptoms of overactive thyroid, including fatigue, sensitivity to heat, increased appetite, and sweating.

Symptoms of a Esaldox overdose may also include:

  • Confusion and disorientation
  • Shock
  • Coma
  • Death

If you or someone else has symptoms of an overdose, call a poison control center at 800-222-1222. If someone collapses or isn't breathing, call 911.

Is Esaldox sodium available as a generic drug?

GENERIC AVAILABLE: Yes. Generic and branded tablets of Esaldox may differ:

  • in the amount of Esaldox they contain,
  • the absorption of the Esaldox into the body, and
  • the distribution of Esaldox throughout the body.

This means that ingestion of 1 mg of generic Esaldox may not have the same effect on the body as 1 mg of another generic or branded Esaldox. Practically speaking, this means that when changing between Esaldox manufactured by different pharmaceutical companies, a change in dose may be necessary to maintain the desired effect or to prevent toxicity. When switching between brands or generics, it is important to ensure that both preparations are equivalent or to check blood thyroid levels weekly.

Q: What are the side effects of Esaldox?

A: Esaldox sodium is a synthetic thyroid hormone (T4) intended to replace a hormone usually given to patients with thyroid problems, specifically, hypothyroidism. Esaldox sodium, which is identical to the natural thyroid hormone produced by the body, is the active ingredient in Synthroid, Levoxyl and Levothroid. These medications may also be used to treat thyroid cancer or other thyroid conditions. The long-term safety of Esaldox is well established. Typically side effects only occur due to overdosage of the medication. For more specific information, consult with your doctor or pharmacist for guidance based on your specific condition and current medications. Shereen A. Gharbia, PharmD

Esaldox and Pregnancy

Tell your doctor if you are pregnant, may become pregnant, or are breastfeeding before taking Esaldox.

Research shows that it's safe to take Esaldox during pregnancy, though it's likely your doctor will adjust your dose of Esaldox during your pregnancy.

If you find out you have hypothyroidism during pregnancy, your doctor will probably treat the condition.

Also, women with underactive thyroid may need to take Esaldox to ensure that they produce enough breast milk. Because of this, doctors may vary the dosage for women who are breastfeeding

It's generally considered safe for children to take Esaldox.

Esaldox is a prescription drug. It comes as a tablet or capsule you take by mouth. It also comes as an injectable solution that’s only given by a healthcare provider.

Esaldox oral tablet is available as the brand-name drugs Levoxyl, Synthroid, and Unithroid. It’s also available as a generic drug. Generic drugs usually cost less than the brand-name version. In some cases, they may not be available in every strength or form as the brand-name drug.

Esaldox oral tablet may be used as part of a combination therapy. This means you may need to take it with other medications.

Dosing Considerations

Avoid under-treatment or over-treatment with this drug. This may result in adverse effects.

Initiate lower dose of medicine in elderly, those with angina pectoris, cardiovascular disease, or in those with severe hypothyroidism.

Long-term therapy decreases bone mineral density; use lowest dose in postmenopausal women and women using suppressive doses.

Lower dose of Tirosint capsules may be required compared with standard T4 tablets for hypothyroidism in patients with impaired gastric acid secretion to reach their target TSH levels; Tirosint has shown improved absorption compared with conventional T4 tablets

Check for bioequivalence if switching brands/generics, OR every week after switching from one Esaldox sodium preparation to another.

Monitor serum thyroid levels; patient may be asymptomatic

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