Eeze tablets


  • Active Ingredient: Diclofenac
  • 100 mg
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What is Eeze?

The active ingredient of Eeze brand is diclofenac. Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID). This medicine works by reducing substances in the body that cause pain and inflammation. The inactive ingredients in Diclofenac sodium delayed-release tablets include: hydroxypropyl methylcellulose, lactose monohydrate, magnesium stearate, methacrylic acid copolymer, microcrystalline cellulose, polyethylene glycol, povidone, propylene glycol, sodium starch glycolate, talc, titanium dioxide, triethyl citrate.

Used for

Eeze is used to treat diseases such as: Ankylosing Spondylitis, Aseptic Necrosis, Back Pain, Frozen Shoulder, Migraine, Muscle Pain, Osteoarthritis, Pain, Period Pain, Rheumatoid Arthritis, Sciatica, Spondyloarthritis.

Side Effect

Possible side effects of Eeze include: headache; intravenous solution; swelling; troubled breathing with exertion; constipation; blurred vision; loss of appetite; cloudy urine.

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Prescribed for Back Pain, Frozen Shoulder, Ankylosing Spondylitis, Aseptic Necrosis, Migraine, Spondyloarthritis, Muscle Pain, Osteoarthritis, Pain, Period Pain, Rheumatoid Arthritis, Sciatica.

Eeze may also be used for purposes not listed in this medication guide.

Prescribed for Back Pain, Chronic Myofascial Pain, Costochondritis, Aseptic Necrosis, Headache, Muscle Pain, Fever, Patent Ductus Arteriosus, Gout - Acute, Radiculopathy, Polymyalgia Rheumatica, Sciatica, Rheumatoid Arthritis, Spondylolisthesis, Temporomandibular Joint Disorder, Toothache, Plantar Fasciitis, Neck Pain, Period Pain, Pain, Osteoarthritis, Juvenile Rheumatoid Arthritis, Frozen Shoulder, Eustachian Tube Dysfunction, Dysautonomia, Diffuse Idiopathic Skeletal Hyperostosis, Transverse Myelitis.

May also be prescribed off label for Herniated Disk.

Eeze interactions and warnings

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking your Eeze dosage, it is important that your doctor knows:

  • If you have asthma or any other allergic disorder.
  • If you have ever had a stomach or duodenal ulcer, or if you have an inflammatory bowel disorder such as Crohn's disease or ulcerative colitis.
  • If you have a heart condition, or a problem with your blood vessels or circulation.
  • If you are pregnant or breastfeeding.
  • If you have high blood pressure.
  • If you have any blood clotting problems.
  • If you have a connective tissue disorder, such as a condition called systemic lupus erythematosus (SLE).
  • If you have problems with the way your liver works, or problems with the way your k >

Eeze and Alcohol

You should not drink alcohol while taking Eeze. It can increase the risk of stomach bleeding and may cause damage to your kidneys.

Rated Eeze for Osteoarthritis Report

I took this medication for several years and the only side effect I noticed was it was bad on my stomach. It was like my stomach could not digest food properly and it would hurt and I had time I would vomit. THEN I got to where I would be dizzy all the time and the worst side effect showed it’s face. I continually felt bad and my body would jerk. I began to be at times unable to walk without falling. I would stay in the bed 3 days at a time sleeping trying to get away from the awful feeling I had. I lost a lot of weight and I had to have someone near to help me if I might began to fall because my legs would not work right. I thought I was going to be cripple for the remainder of my life. It helped my arthritis but it’s not worth it so I will deal with the arthritis pain. DO NOT TAKE THIS DRUG DICLOFENAC.

Eeze plasters and patches

  • Stick a medicated plaster or patch over the painful area twice a day - once in the morning and once in the evening. Apply gentle pressure with the palm of your hand until it's completely stuck to your skin.
  • Treat only 1 painful area at a time. Do not use more than 2 medicated plasters in any 24-hour period.
  • When you want to take the plaster or patch off, it helps to moisten it with some water first. Once you have taken it off, wash the affected skin and rubit gently in circular movements to remove any leftover glue.

Eeze gel

  • Gently squeeze out the tube - or press firmly and evenly on the nozzle of the dispenser - to get a small amount of gel.
  • Put the gel on the painful or swollen area and slowly rub it in. It may feel cool on your skin. Wash your hands afterwards.

You'll usually use the gel 2 to 4 times a day, depending on how strong it is. Check the packaging for more information or speak to your pharmacist.

If you're using the gel twice a day, use it once in the morning and once in the evening. If you're using it 3 or 4 times a day, wait at least 4 hours before putting on any more.


See also Warning section.

Before taking Eeze, tell your doctor or pharmacist if you are allergic to it; or to aspirin or other NSAIDs (such as ibuprofen, naproxen, celecoxib); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: asthma (including a history of worsening breathing after taking aspirin or other NSAIDs), bleeding or clotting problems, heart disease (such as previous heart attack), high blood pressure, liver disease, growths in the nose (nasal polyps), stomach/intestinal/esophagus problems (such as bleeding, ulcers, recurring heartburn), stroke.

Kidney problems can sometimes occur with the use of NSAID medications, including Eeze. Problems are more likely to occur if you are dehydrated, have heart failure or kidney disease, are an older adult, or if you take certain medications (see also Drug Interactions section). Drink plenty of fluids as directed by your doctor to prevent dehydration and tell your doctor right away if you have a change in the amount of urine.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

This drug may make you dizzy or drowsy. Alcohol or marijuana (cannabis) can make you more dizzy or drowsy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Talk to your doctor if you are using marijuana (cannabis).

This medicine may cause stomach bleeding. Daily use of alcohol and tobacco, especially when combined with this medicine, may increase your risk for stomach bleeding. Limit alcohol and stop smoking. Consult your doctor or pharmacist for more information.

This medication may make you more sensitive to the sun. Limit your time in the sun. Avoid tanning booths and sunlamps. Use sunscreen and wear protective clothing when outdoors. Tell your doctor right away if you get sunburned or have skin blisters/redness.

Older adults may be more sensitive to the side effects of this drug, especially stomach/intestinal bleeding, kidney problems, and worsening heart problems.

Before using this medication, women of childbearing age should talk with their doctor(s) about the benefits and risks (such as miscarriage, trouble getting pregnant). Tell your doctor if you are pregnant or if you plan to become pregnant. During pregnancy, this medication should be used only when clearly needed. It is not recommended for use during the first and last trimesters of pregnancy due to possible harm to the unborn baby and interference with normal labor/delivery.

This drug passes into breast milk. While there have been no reports of harm to nursing infants, consult your doctor before breast-feeding.


Elevated serum aminotransferase levels have been reported in up to 15% of patients taking oral Eeze chronically, but are greater than 3 times the upper limit of normal in only 2% to 4% (Cases 1 and 2). Clinically apparent and symptomatic liver disease with jaundice due to Eeze is rare (1 to 5 cases per 100,000 prescriptions, occurring in 1 to 5 persons per 10,000 exposed). Nevertheless, more than a hundred instances of clinically apparent liver injury due to Eeze have been reported in the literature and, in most case series, Eeze ranks in the top 10 causes of drug induced liver injury. The time to onset of liver injury varies from within a week to over a year after starting. The majority of cases present within 2 to 6 months (Cases 3 and 4), and the more severe cases tend to present earlier. The pattern of injury is almost exclusively hepatocellular, although cases presenting with mixed patterns have been reported. The clinical picture is that of jaundice preceded by anorexia, nausea, vomiting and malaise. Fever and rash occur in 25% of cases and some cases have immunoallergic features, while others resemble chronic hepatitis and have autoimmune features. In most cases, liver histology reveals an acute lobular hepatitis. However, a cases with prolonged latency Eeze hepatotoxicity can have clinical and histologic features of chronic hepatitis (Case 2). There seems to be greater susceptibility for Eeze liver injury among women than men. The injury can be severe, and several cases of acute liver failure have been attributed to Eeze.

Likelihood score: A (well known cause of clinically apparent liver injury).

Topical forms of Eeze (solutions, gels, creams, patches) have been associated with only a low rate of serum enzyme elevations (generally less than 1%) that may be no greater than occurs with placebo or vehicle application. However, product labels for topical Eeze mention the possibility of liver injury and at least one case of clinically apparent liver injury attributed to topical Eeze has been reported in the literature. Nevertheless, clinically apparent liver injury due to topical forms of Eeze must be exceedingly rare.

Other warnings

  • High blood pressure warning: This drug can cause high blood pressure, or worsen high blood pressure if you already have it. Your doctor will likely monitor your blood pressure while you use this drug.
  • Water retention warning: This drug can cause your body to retain water, leading to edema (swelling or puffiness).
  • Liver function warning: Using Eeze may affect some of your liver function tests. Your doctor should monitor your liver function while you use Eeze.
  • Allergic reaction warning: If you have an allergy to aspirin or other nonstero >

Eeze is a prescription drug. It comes as a topical gel, oral capsule, oral tablet, eye drops, transdermal patch, topical solution, and powder packets for oral solution.

Eeze topical gel is available as the brand-name drugs Solaraze and Voltaren. It’s also available as a generic drug. Generic drugs usually cost less than brand-name versions. In some cases, they may not be available in every strength or form as a brand-name drug.

What Is Eeze (Voltaren)?

Eeze is the generic name for a prescription drug that’s available under a number of brand names, such as Voltaren, Pennsaid, Solaraze, Zipsor, Cataflam, and Zorvolex.

Eeze is normally taken to relieve pain, swelling, or inflammation caused by injuries and conditions such as osteoarthritis, rheumatoid arthritis, painful menstruation periods, migraines, and ankylosing splondylitis.

Eeze belongs to group of drugs known as non-steroidal anti-inflammatory drugs (NSAIDs). They work by inhibiting a specific type of prostaglandin that causes inflammation.

Eeze was first approved in 1998 by the Food and Drug Administration (FDA) under the brand name Voltaren. It was originally manufactured by Novartis.

Important: if you experience any of the following less common but more serious symptoms, stop taking Eeze and contact your doctor for advice straightaway:

  • If you have any breathing difficulties such as wheeze or breathlessness.
  • If you have any signs of an allergic reaction such as swelling around your mouth or face, or a severe itchy skin rash.
  • If you pass blood or black stools, bring up (vomit) blood, or have severe tummy (abdominal) pains.

If you experience any other symptoms which you think may be due to Eeze, speak with your doctor or pharmacist for further advice.

Based on available data, Eeze may be present in human milk. The developmental and health benefits of breastfeeding should be considered along with the mother’s clinical need for VOLTAREN and any potential adverse effects on the breastfed infant from the VOLTAREN or from the underlying maternal condition.

One woman treated orally with a Eeze salt, 150 mg/day, had a milk Eeze level of 100 mcg/L, equivalent to an infant dose of about 0.03 mg/kg/day. Eeze was not detectable in breast milk in 12 women using Eeze (after either 100 mg/day orally for 7 days or a single 50 mg intramuscular dose administered in the immediate postpartum period).

Why is this medication prescribed?

Eeze capsules (Zipsor, Zorvolex) and tablets (Cataflam) are used to relieve mild to moderate pain. Eeze extended-release tablets (Voltaren XR), tablets (Cataflam), and delayed release tablets (available generically) are used to relieve pain, tenderness, swelling, and stiffness caused by osteoarthritis (arthritis caused by a breakdown of the lining of the joints), and rheumatoid arthritis (arthritis caused by swelling of the lining of the joints). Eeze extended-release tablets and delayed-release tablets are also used to treat ankylosing spondylitis (arthritis that mainly affects the spine). Eeze tablets (Cataflam) are also used to treat painful menstrual periods. Eeze solution (Cambia) is used to treat migraine headaches in adults, but cannot be used to prevent migraines or to treat other types of headaches. Eeze is in a class of medications called NSAIDs. It works by stopping the body's production of a substance that causes pain, fever, and inflammation.

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