Depreks tablets

Depreks

  • Active Ingredient: Fluoxetine
  • 20 mg, 10 mg
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What is Depreks?

The active ingredient of Depreks brand is fluoxetine. Fluoxetine is a selective serotonin reuptake inhibitors (SSRI) antidepressant. Fluoxetine affects chemicals in the brain that may be unbalanced in people with depression, panic, anxiety, or obsessive-compulsive symptoms. C17H18F3NO•HCl M.W. 345.79 Fluoxetine hydrochloride, USP is a white to off-white crystalline solid with a solubility of 14 mg/mL in water. Each tablet contains Fluoxetine hydrochloride, USP equivalent to 10 mg (32.3 μmol) of Fluoxetine. In addition, each tablet also contains the following inactive ingredients: D&C Yellow #10 aluminum lake, FD&C Blue #2 aluminum lake, FD&C Yellow #6 aluminum lake, hypromellose, lactose monohydrate, magnesium stearate, microcrystalline cellulose, polyethylene glycol, povidone, pregelatinized corn starch, talc, and titanium dioxide.

Used for

Depreks is used to treat diseases such as: Anxiety and Stress, Binge Eating Disorder, Body Dysmorphic Disorder, Borderline Personality Disorder, Bulimia, Depression, Dissociative Identity Disorder, Dysautonomia, Fibromyalgia, Hot Flashes, Intermittent Explosive Disorder, Major Depressive Disorder, Obsessive Compulsive Disorder, PANDAS Syndrome, Panic Disorder, Persistent Depressive Disorder, Postpartum Depression, Premature Ejaculation, Premenstrual Dysphoric Disorder, Schizoaffective Disorder, Somatoform Pain Disorder, Trichotillomania, Vulvodynia.

Side Effect

Possible side effects of Depreks include: shivering or shaking; increased sweating; unusual tiredness or weakness; drowsiness; blindness.

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FDA warning: Suic >
  • This drug has a black box warning. This is the most serious warning from the Food and Drug Administration (FDA). A black box warning alerts doctors and patients about drug effects that may be dangerous.
  • Depreks can increase the risk of suicidal thinking and behavior. This risk is especially high in children, adolescents, and young adults. The risk is higher during the first few months of treatment with this drug. You’re also at higher risk if you have a personal or family history of bipolar illness or suicidal thoughts or actions. Your doctor and family should watch you closely when you start taking this drug and during dosage changes. They should watch for changes in your behavior or signs of worsening depression.

Q: What are the side effects of a Prozac overdose?

A: Prozac (Depreks) is prescription medication commonly used to treat depression, generalized anxiety disorder, obsessive-compulsive disorder, and panic disorder. Prozac should be taken regularly, at the same time every day, with or without food. Prozac can be taken at any time during the day, but should be taken around the same time every day. Pick a time that is easy to remember and works well with your schedule and other medications you might be taking. It can take four weeks or longer before you see the benefits of Prozac. Take Prozac exactly as prescribed. Do not stop taking Prozac without first talking to your healthcare provider. Stopping Prozac suddenly could result in withdrawal side effects. Common side effects associated with treatment with Prozac include headache, dry mouth, nausea, diarrhea, sweating, flushing, blurred vision, changes in appetite and sex drive. This is not a complete list of side effects associated with Prozac. If you experience any symptoms that are unusual or bothersome, contact your healthcare provider. Too much Prozac can cause a life-threatening condition known as serotonin syndrome. Signs and symptoms of serotonin syndrome may include agitation, restlessness, confusion, rapid heart rate, dilated pupils, loss of muscle coordination, heavy sweating, diarrhea, headache, shivering, and goose bumps. Contact your doctor immediately if you have any of these serious symptoms of serotonin syndrome or think you have taken a Prozac overdose. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. Jennifer Carey, PharmD

Q: Is Prozac for insomnia?

A: Prozac (Depreks) is not indicated for insomnia treatment by the U.S. Food and Drug Administration (FDA). Prozac is approved by the FDA for the treatment of several other medical conditions including depression, obsessive-compulsive disorder, bulimia nervosa and panic disorder. During clinical trials, one of the most commonly observed adverse reactions in patients being treated with Prozac, for any indication, was insomnia. During placebo-controlled clinical trials for major depressive disorder, Prozac caused insomnia in 16% of patients being evaluated. In trials evaluating Prozac for obsessive-compulsive disorder, 28% of patients reported insomnia as an adverse reaction associated with treatment. During the clinical trials of bulimia, 33% of patients reported experiencing insomnia caused by Prozac. Finally, in the clinical studies of patients with panic disorder, Prozac precipitated insomnia in 10% of patients. Overall, for all indications combined, the incidence of Prozac causing insomnia was reported by 19% of patients. According to the prescribing information, insomnia was one of the most common adverse reactions associated with discontinuation of Prozac in patients with bulimia, with 2% of patients discontinuing treatment. Patients should be advised to take Prozac exactly as directed by their health care provider. If patients experience unpleasant or bothersome adverse reactions, such as insomnia, they are also advised not to change their dosing regimen or discontinue treatment without consulting with their health care provider.

Precautions

Before taking Depreks, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: personal or family history of bipolar/manic-depressive disorder, personal or family history of suicide attempts, liver problems, diabetes, low sodium in the blood (such as may occur while taking "water pills" - diuretics), severe loss of body water (dehydration), seizures, stomach/intestinal ulcers, personal or family history of glaucoma (angle-closure type).

This drug may make you dizzy or drowsy. Alcohol or marijuana (cannabis) can make you more dizzy or drowsy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Avoid alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis).

The liquid form of this medication contains alcohol. Caution is advised if you have diabetes, alcohol dependence, or liver disease. Some medications (such as metronidazole, disulfiram) can cause a serious reaction when combined with alcohol. Ask your doctor or pharmacist about using this product safely.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Children may be more sensitive to the side effects of this drug, especially weight loss. Monitor weight and height in children who are taking this drug.

Older adults may be more sensitive to the side effects of this drug, especially bleeding and loss of coordination. Loss of coordination can increase the risk of falling. Older adults may also be more likely to develop low sodium in the blood, especially if they are taking "water pills" (diuretics).

During pregnancy, this medication should be used only when clearly needed. It may harm an unborn baby. Also, babies born to mothers who have used this drug during the last 3 months of pregnancy may rarely develop withdrawal symptoms such as feeding/breathing difficulties, seizures, muscle stiffness, or constant crying. If you notice any of these symptoms in your newborn, tell the doctor promptly.

Since untreated mental/mood problems (such as depression, panic attacks, obsessive compulsive disorder) can be a serious condition, do not stop taking this medication unless directed by your doctor. If you are planning pregnancy, become pregnant, or think you may be pregnant, immediately discuss the benefits and risks of using this medication during pregnancy with your doctor.

This medication passes into breast milk and may have undesirable effects on a nursing infant. Consult your doctor before breast-feeding.

What Other Drugs Interact with Depreks?

If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first.

Severe Interactions of Depreks include:

Depreks has serious interactions with at least 101 different drugs.

Depreks has moderate interactions with at least 235 different drugs.

Depreks has mild interactions with at least 43 different drugs.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist. Check with your physician if you have health questions or concerns.

1. About Depreks

Depreks is a type of antidepressant known as an SSRI (selective serotonin reuptake inhibitor).

It is often used to treat depression, and also sometimes obsessive compulsive disorder and bulimia.

Depreks helps many people recover from depression, and it has fewer unwanted effects than older antidepressants.

Depreks is available only on prescription. It comes as tablets and capsules.

Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Depreks can stay in your body for many weeks after your last dose and may interact with many other medications. Before using any medication, tell your doctor or pharmacist if you have taken Depreks in the previous 5 weeks.

Some products that may interact with this drug include: other drugs that can cause bleeding/bruising (including antiplatelet drugs such as clopidogrel, NSAIDs such as ibuprofen, "blood thinners" such as warfarin).

Taking MAO inhibitors with his medication may cause a serious (possibly fatal) drug interaction. Avoid taking MAO inhibitors (isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, tranylcypromine) during treatment with this medication. Most MAO inhibitors should also not be taken for 2 weeks before and at least 5 weeks after treatment with this medication. Ask your doctor when to start or stop taking this medication.

This medication can slow down the removal of other medications from your body, which may affect how they work. Examples of affected drugs include pimozide, thioridazine, vinblastine, antiarrhythmics (such as propafenone, flecainide), tricyclic antidepressants (such as desipramine, imipramine), among others.

Aspirin can increase the risk of bleeding when used with this medication. However, if your doctor has directed you to take low-dose aspirin for heart attack or stroke prevention (usually at dosages of 81-325 milligrams a day), you should continue taking it unless your doctor instructs you otherwise.

The risk of serotonin syndrome/toxicity increases if you are also taking other drugs that increase serotonin. Examples include street drugs such as MDMA/"ecstasy," St. John's wort, certain antidepressants (including other SSRIs such as citalopram/paroxetine, SNRIs such as duloxetine/venlafaxine), tryptophan, among others. The risk of serotonin syndrome/toxicity may be more likely when you start or increase the dose of these drugs.

Tell your doctor or pharmacist if you are taking other products that cause drowsiness including alcohol, marijuana (cannabis), antihistamines (such as cetirizine, diphenhydramine), drugs for sleep or anxiety (such as alprazolam, diazepam, zolpidem), muscle relaxants, and narcotic pain relievers (such as codeine). Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain ingredients that cause drowsiness. Ask your pharmacist about using those products safely.

This medication may interfere with certain medical/laboratory tests (including brain scan for Parkinson's disease), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.

Q: What condition is Prozac used for? Is it used in weight reduction? Is it safe? What are the side effects?

A: Prozac (Depreks) is a medication that is used to treat depression, panic disorder, obsessive compulsive disorder (OCD), depression associated with bipolar disorder, as well as other conditions. It is in the class of medications called selective serotonin reuptake inhibitors (SSRIs) and works by bringing a balance to serotonin in the brain that may be the cause of symptoms. The prescribing information on Prozac lists the following as the most common side effects associated with the medication: insomnia, nausea, diarrhea, headache, loss of appetite, drowsiness, anxiety, tremor, dry mouth, decreased sex drive, yawning, indigestion, dizziness and sweating. Prozac is not approved by the U.S. Food and Drug Administration (FDA) for weight loss. Weight loss appears to be a side effect that occurs in up to 2 percent of patients taking Prozac. It is not entirely clear why this medication causes weight loss, although it is generally a small amount. It may be due to the side effects of loss of appetite, diarrhea and nausea that may contribute to the weight loss. Lori Poulin, PharmD

What other information should I know?

Keep all appointments with your doctor.

Before having any laboratory test (especially those that involve methylene blue), tell your doctor and the laboratory personnel that you are taking Depreks.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Q: Can Depreks (Prozac) be taken with Adipex (phentermine)?

A: Studies suggest that these medications can be taken together in healthy adults. Without evaluating a patient's lab results for such factors as liver and kidney function, I am unable to make recommendations. Please consult with your physician for specific recommendations. Please see //www.everydayhealth.com/drugs/prozac and //www.everydayhealth.com/drugs/phentermine.

Q: Could taking Prozac cause me to have a delay in speaking or stutter at all?

A: Prozac (Depreks) does list a change in speech and stuttering as possible side effects. If you are experiencing this side effect, and it is not tolerable, you may want to consult your doctor to see if an alternative medication may be better for you. There are many antidepressants available, and some work better than others for people. If you would like more information on depression and medications, please visit our links at: //www.everydayhealth.com/depression/guide/, and //www.everydayhealth.com/drugs/. Patti Brown, PharmD

Prozac Warnings

Prozac and other antidepressants are required to carry a black box warning due to the increased risk of suicide when taking the medicine.

Prozac may increase suicidal thoughts or actions in children, teenagers, and young adults within the first several months of treatment or after a change in dose.

Call your doctor immediately if you have any unusual changes in behavior or mood while on Prozac, including:

  • Thoughts about suicide or dying, or suicide attempts
  • New or worsening depression or anxiety
  • Feeling very agitated or restless
  • Panic attacks
  • Difficulty sleeping
  • New or worse irritability
  • Being aggressive, angry, or violent
  • Acting on dangerous impulses
  • Extreme increase in activity and talking
  • Decreased need for sleep

Before taking Prozac, tell your doctor if you have a history of seizures; bipolar disorder; liver disease; heart problems, including heart rhythm problems; diabetes; glaucoma; or thoughts of suicide or attempted suicide.

You may not feel the full benefits of Prozac for 4 to 6 weeks or longer after starting the medication.

Before stopping Prozac, talk to your doctor. Stopping suddenly can cause serious side effects. Your doctor will help you safely stop the medication.

Don't take Prozac or other forms of Depreks if you're allergic to Depreks or any of the inactive ingredients in the various formulations. Cases of severe allergic reactions have been reported and could result in death.

If you are taking a monoamine oxidase inhibitor (MAOI) or if you took an MAOI in the past 14 days, then don't use Prozac. A dangerous drug interaction could occur that may result in death.

Avoid operating heavy machinery, driving a motor vehicle, or performing other dangerous activities until you know how Prozac affects you.

The drug can cause sleepiness and may worsen your ability to make decisions, think clearly, or react quickly.

There is limited information regarding the long-term effects of Prozac on the development and maturation of children and adolescents.

Talk to your child's doctor about monitoring their height and weight when they are taking Prozac.

Q: Does Prozac cause weight gain?

A: Prozac (Depreks) is classified as a selective serotonin reuptake inhibitor (SSRI) antidepressant. Prozac is approved for the treatment of depression, binge-eating, and vomiting in patients with bulimia, obsessive compulsive disorder (OCD), premenstrual dysphoric disorder (PMDD), panic disorder and with other medication to treat bipolar disorder. According to medical references, weight gain is a possible reported side effect of Prozac. Increased appetite and weight loss are also listed side effects of the medication. These are not a complete list of side effects associated with the use of Prozac. Drugs can cause weight gain in several different ways. Some can increase appetite or make you crave certain types of foods like those high in carbohydrates or fat. Other medications may slow down metabolism or cause fluid retention. However, the effect of prescription drugs on body weight is complex. Some drugs have no effect on weight, while others cause weight gain or weight loss. Also, the same medications can cause weight gain in certain individuals and weight loss in others. There are also drugs that initially cause weight loss and then lead to weight gain with long-term use. Most prescription medications associated with changes in body weight affect the central nervous system. These include antidepressants like monoamine oxidase inhibitors (MAOIs), tricyclic antidepressants, and selective serotonin reuptake inhibitors (SSRIs). Mood stabilizers (lithium, valproic acid), antipsychotics, and anticonvulsants have also been linked with weight gain. Other drugs that have been reported to cause weight gain include diabetes medications (insulin, sulfonylureas, and thiazolidinediones), antihypertensive drugs, certain hormonal contraceptives, corticosteroids, antihistamines, some chemotherapy regimens, and antiretroviral protease inhibitors. If you think a drug you are taking is causing weight gain, tell your health care provider. Do not stop any medication or change the dose without first talking to your provider. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. Jen Marsico, RPh

What should I avoid while taking Depreks?

Drinking alcohol can increase certain side effects of Depreks.

Ask your doctor before taking a nonsteroidal anti-inflammatory drug (NSAID) for pain, arthritis, fever, or swelling. This includes aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib (Celebrex), diclofenac, indomethacin, meloxicam, and others. Using an NSAID with Depreks may cause you to bruise or bleed easily.

This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.


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