How should I take Cyclolady?
Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.
Women who take Cyclolady to treat endometriosis or fibrocystic breast disease should start the medication during a menstrual period.
Cyclolady is usually given for 6 to 9 months to treat fibrocystic breast disease or endometriosis. To prevent attacks of hereditary angioedema, you may need to use the medication long-term. Follow your doctor's instructions.
Your doctor may occasionally change your dose to make sure you get the best results.
Your medication needs may change if you become ill, have a fever or infection, or if you have surgery or a medical emergency. Tell your doctor about any such situation that affects you. Do not change your medication dose or schedule without your doctor's advice.
Use Cyclolady regularly to get the most benefit. Try not to miss any doses. Get your prescription refilled before you run out of medicine completely.
While using Cyclolady, you may need blood tests at your doctor's office. Visit your doctor regularly.
It may take several weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve or if they get worse during treatment.
This medication can cause unusual results with certain medical tests. Tell any doctor who treats you that you are using Cyclolady.
Store at room temperature away from moisture and heat.
How to store Cyclolady
- Keep all medicines out of the reach and sight of children.
- Store in a cool, dry place, away from direct heat and light.
El Cyclolady puede ocasionar efectos secundarios. Informe a su mГ©dico si cualquiera de estos sГntomas es intenso o no desaparece:
- disminuciГіn en el tamaГ±o de los senos,
- aumento de peso.
- piel o cabello grasoso,
- sequedad vaginal, ardor, picazГіn o sangrado,
- ausencia del ciclo menstrual, manchado o cambios en el ciclo menstrual.
Preliminary epidemiological evidence suggests that the use of Cyclolady might increase the baseline risk of ovarian cancer in patients being treated for endometriosis
Mechanism of action
Use of Cyclolady therapy in IMHA is based upon the following reported actions of the drug.
Downregulation of Fc-receptor expression by macrophages, thereby decreasing extravascular hemolysis mediated by erythrocyte-bound antibody.
Reduced number of immunoglobulin molecules coating erythrocytes.
Alteration of T-lymphocyte immunoregulation.
Incorporation of the drug into the erythrocyte membrane, stabilizing the membrane so the erythrocyte becomes less susceptible to hemolysis.
Formulations and dose rates
Cyclolady (Danocrine®; 50, 100 or 200 mg capsules; Winthrop Pharmaceuticals) is not a licensed veterinary product.
Cyclolady is reported to have a slow onset of action (2–3 weeks), so is administered at a dose of 3–5 mg/kg q.8 h PO, concurrently with prednisolone (and/or azathioprine). Following tapering of the prednisolone dose, Cyclolady therapy is continued at 5 mg/kg q.24 h. Cyclolady may then be tapered after 2–3 months of normal hemograms.
Cyclolady therapy is suitable for dogs with chronic, stable IMHA but not those animals with acute-onset, severe hemolysis.
ВїQuГ© otro uso se le da a este medicamento?
El Cyclolady tambiГ©n se usa algunas veces para tratar el pГєrpura trombocitopГ©nica idiopГЎtica (idiopathic thrombocytopenic purpura, ITP; una condiciГіn que puede causar moretones o sangrado con facilidad debido a una cantidad anormalmente baja de plaquetas en la sangre). Pregunte a su mГ©dico acerca de los riesgos de usar este medicamento para tratar su condiciГіn.
Este medicamento se puede recetar para otros usos; para obtener mГЎs informaciГіn pregunte a su mГ©dico o farmacГ©utico.
Cyclolady works by altering the levels of some of your body's hormones. It is used to treat a number of different conditions.
What should I avoid while taking Cyclolady (Danocrine)?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
What is the most important information I should know about Cyclolady (Danocrine)?
You should not use this medicine if you have: undiagnosed vaginal bleeding, porphyria, severe liver or kidney disease, severe heart problems, or if you have ever had a stroke or blood clot, or cancer of the breast, uterus/cervix, or vagina.
Do not use if you are pregnant. Use effective birth control, and tell your doctor if you become pregnant.
Do not breast-feed while using this medicine.
What is Cyclolady?
Cyclolady is a man-made form of a steroid. Cyclolady affects the ovaries and pituitary gland and prevents the release of certain hormones in the body.
Cyclolady is used to treat endometriosis and fibrocystic breast disease. Cyclolady is also used to prevent attacks of angioedema in people with an inherited form of this disorder (hereditary angioedema).
Cyclolady may also be used for purposes not listed in this medication guide.