Cabest tablets

Cabest

  • Active Ingredient: Cabergoline
  • 0.5 mg
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What is Cabest?

The active ingredient of Cabest brand is cabergoline. Cabergoline is a dopamine receptor agonist. It works by reducing the amount of prolactin (a hormone) that is released from the pituitary gland.

Used for

Cabest is used to treat diseases such as: Hyperprolactinemia.

Side Effect

Possible side effects of Cabest include: dizziness; vomiting; Bloody nose; breast pain; dry mouth or toothache.

How to Buy Cabest tablets online?

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Cabest and Alcohol

Alcohol may worsen certain side effects of Cabest.

Talk to your doctor before drinking alcohol while taking this drug.

Manufacturer

This Cabest 1mg or 0.5mg drugs is manufactured by India’s most trusted pharmacy called Eskag pharma private limited.

Uses of Cabest:

  • It is used to treat health problems where there are high prolactin levels.
  • It may be given to you for other reasons. Talk with the doctor.

Pregnancy and Cabest

Cabest isn't likely to harm an unborn baby, but be sure to tell your doctor if you're pregnant or might become pregnant while taking this medicine.

It's not known whether Cabest can pass into breast milk.

Tell your doctor if you're breastfeeding or plan to breastfeed while taking this drug, as it may slow or stop the production of breast milk.

Why it's used

Cabest is used to treat hyperprolactinemia (high levels of prolactin in your body). This happens when your pituitary gland makes extra prolactin. High prolactin levels may be caused by a hormone problem or by a tumor in your pituitary gland.

High prolactin levels can cause changes in a woman’s ovulation, menstrual cycle, and breast milk production. In men, high prolactin levels can affect reproduction and cause sexual issues. These issues include a decreased sex drive and not being able to get or keep an erection.

Cabest

A selective, potent, long-acting dopamine antagonist that suppresses prolactin secretion and restores gonadal function in women with hyperprolactinaemic amenorrhoea; it is more effective and better tolerated than bromocriptine, which must be injected 2–3 times/day, compared to 1–2 weekly for Cabest.

Adverse effectsSevere allergic reactions, chest tightness, behavioural changes (e.g., aggression, increased gambling or sexual urges, confusion, depression), hallucinations, chest pain, cough, arrhythmias, shortness of breath, unexplained weight gain, acral oedema, vision disturbances.

Cabest

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COMMON BRAND(S): Dostinex

GENERIC NAME(S): Cabest

OTHER NAME(S): Cabest Tablet

This medication is used to treat high levels of prolactin hormone in your body. High levels of prolactin in women can cause symptoms such as unwanted breast milk and missed periods and can cause difficulty becoming pregnant. High levels of prolactin in men can cause symptoms such as enlarged breasts and decreased sexual ability/desire. Cabest is an ergot medication and works by blocking the release of prolactin from the pituitary gland.

What is the dosage for Cabest and how should I take it?

The recommended dosage of Cabest tablets for initiation of therapy is 0.25 mg twice a week. Dosage may be increased by 0.25 mg twice weekly up to a dosage of 1 mg twice a week according to the patient’s serum prolactin level. Before initiating treatment, cardiovascular evaluation should be performed and echocardiography should be considered to assess for valvular disease.

Dosage increases should not occur more rapidly than every 4 weeks, so that the physician can assess the patient’s response to each dosage level. If the patient does not respond adequately, and no additional benefit is observed with higher doses, the lowest dose that achieved maximal response should be used and other therapeutic approaches considered.

Patients receiving long-term treatment with Cabest should undergo periodic assessment of their cardiac status and echocardiography should be considered.

After a normal serum prolactin level has been maintained for 6 months, Cabest may be discontinued, with periodic monitoring of the serum prolactin level to determine whether or when treatment with Cabest should be reinstituted. The durability of efficacy beyond 24 months of therapy with Cabest has not been established.

Cabest is better tolerated when administered with food.

All patients should undergo a cardiovascular evaluation, including echocardiogram to assess the potential presence of valvular disease. If valvular disease is detected, the patient should not be treated with DOSTINEX. (See CONTRAINDICATIONS) Postmarketing cases of cardiac valvulopathy have been reported in patients receiving DOSTINEX. These cases have generally occurred during administration of high doses of DOSTINEX ( > 2mg/day) for the treatment of Parkinson's disease. Cases of cardiac valvulopathy have also been reported in patients receiving lower doses of DOSTINEX for the treatment of hyperprolactinemic disorders.

A multi-country, retrospective cohort study using general practice records and record linkage systems in the UK, Italy and the Netherlands was conducted to assess the association between new use of dopamine agonists including Cabest (n = 27,812) for Parkinson's disease and hyperprolactinemia and cardiac valvular regurgitation (CVR), other fibroses, and other cardiopulmonary events over a maximum of 12 years of follow up. In this study, the use of Cabest among persons with Parkinson's disease was associated with an increased risk of CVR when compared to non-ergot-derived dopamine agonists (DAs) and levodopa [Inc >

Physicians should use the lowest effective dose of DOSTINEX for the treatment of hyperprolactinemic disorders and should periodically reassess the need for continuing therapy with DOSTINEX. Following treatment initiation, clinical and diagnostic monitoring (for example, chest x-ray, CT scan and cardiac echocardiogram) should be conducted to assess the risk of cardiac valvulopathy. The recommended frequency of routine echocardiographic monitoring is every 6 to 12 months or as clinically indicated with the presence of signs and symptoms such as edema, new cardiac murmur, dyspnea, or congestive heart failure.

DOSTINEX should be discontinued if an echocardiogram reveals new valvular regurgitation, valvular restriction or valve leaflet thickening.

DOSTINEX should be used with caution in patients exposed to other medications associated with valvulopathy.

Where can I get more information (Dostinex)?

Your pharmacist can provide more information about Cabest.

Michael Stewart, Reviewed by Sid Dajani | Last edited 30 Nov 2017 | Certified by The Information Standard

Cabest should be taken with food.

It can cause dizziness, especially during the first few days of treatment.

Each time you collect a fresh supply, check to see if the tablets look the same as you have had before. If they are different, discuss this with your pharmacist who will advise you.

Summary

Cabest is a drug that prevents the production of the prolactin hormone and is used to treat high levels of that hormone in the blood (hyperprolactinemia). Learn about the side effects, dosage, and pregnancy safety information. Dostinex, the brand name, has been discontinued.

home drugs a-z list Dostinex(Cabest) side effects drug center

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Dostinex (Cabest) is a dopamine receptor antagonist used to treat a hormone imbalance in which there is too much prolactin in the blood (also called hyperprolactinemia). Common side effects of Dostinex include:

Tell your doctor if you experience rare but serious side effects of Dostinex including:

  • shortness of breath,
  • persistent cough,
  • swelling ankles or feet,
  • unusual tiredness,
  • mental/mood changes (such as nervousness),
  • unusual strong urges (such as increased gambling, increased sexual urges),
  • vision changes,
  • painful menses, or
  • breast pain.

The recommended starting dosage of Dostinex Tablets is 0.25 mg twice a week. Dosage may be increased by 0.25 mg twice weekly up to a dosage of 1 mg twice a week according to the patient's serum prolactin level. Dostinex may interact with metoclopramide, ACE inhibitors, beta-blockers, calcium channel blockers, diuretics (water pills), or other blood pressure medications. Tell your doctor all medications you use. During pregnancy, Dostinex should be used only when prescribed. It is unknown if this medication passes into breast milk. This medication may affect breast milk production. Breastfeeding while using this drug is not recommended.

Our Dostinex (Cabest) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


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