Xumadol tablets


  • Active Ingredient: Acetaminophen
  • 25 mg
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What is Xumadol?

The active ingredient of Xumadol brand is acetaminophen. There are many brands and forms of acetaminophen available. Not all brands are listed on this leaflet.

Used for

Xumadol is used to treat diseases such as: Fever, Muscle Pain, Neck Pain, Pain, Plantar Fasciitis, Sciatica, Transverse Myelitis.

Side Effect

Possible side effects of Xumadol include: Bloody or black, tarry stools; increased sweating; unusual bleeding or bruising; intravenous solution; sudden decrease in the amount of urine; pain in the lower back and/or side (severe and/or sharp); sore throat (not present before treatment and not caused by the condition being treated).

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What Are Side Effects Associated with Using Xumadol?

Side effects of Xumadol include:

Serious side effects of Xumadol include:

This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.

S >Xumadol causes few side effects. The most common one is lightheadedness. Some people may experience trembling and pain in the side or the lower back. Allergic reactions occur in some people, but are rare. Anyone who develops symptoms such as a rash, swelling, or difficulty breathing after taking Xumadol should stop taking the drug and get immediate medical attention. Other rare side effects include yellow skin or eyes, unusual bleeding or bruising, weakness, fatigue, bloody or black stools, bloody or cloudy urine, and a sudden decrease in the amount of urine.

Xumadol side effects

Get emergency medical help if you have signs of an allergic reaction to Xumadol: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

In rare cases, Xumadol may cause a severe skin reaction that can be fatal. This could occur even if you have taken this medicine in the past and had no reaction. Stop taking this medicine and call your doctor right away if you have skin redness or a rash that spreads and causes blistering and peeling. If you have this type of reaction, you should never again take any medicine that contains Xumadol.

Stop taking Xumadol and call your doctor at once if you have:

nausea, upper stomach pain, itching, loss of appetite;

excessive sweating and severe tiredness;

dark urine, clay-colored stools; or

jaundice (yellowing of the skin or eyes).

The most common side effects of Xumadol include:

nausea and vomiting;

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Q: If you take heart medication and blood thinners, is it safe to take Tylenol?

A: Tylenol (Xumadol) may interact with other medications, including some heart medicines and blood thinners. In order to completely answer your question about drug interactions, we need the names of each medication you are currently taking. If you would like to try again or submit a new question, please return to the Ask a Pharmacist page at www.everydayhealth.com/drugs. Michelle McDermott, PharmD


Do not use if pouch is opened

Liver warning: This product contains Xumadol. Severe liver damage may occur if:

  • adult takes more than 12 caplets in 24 hours, which is the maximum daily amount
  • child takes more than 5 doses in 24 hours, which is the maximum daily amount
  • taken with other drugs containing Xumadol
  • adult has 3 or more alcoholic drinks every day while using this product.

  • with any other drug containing Xumadol (prescription or nonprescription). If you are not sure whether a drug contains Xumadol, ask a doctor or pharmacist.
  • if you are allergic to Xumadol or any of the inactive ingredients in this product

Stop use and ask a doctor if

  • pain gets worse or lasts more than 10 days in adults
  • pain gets worse or lasts more than 5 days in children under 12 years
  • fever gets worse or lasts more than 3 days
  • new symptoms occur
  • redness or swelling is present

These could be signs of a serious condition.

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children.

Ask a doctor before use if the user has liver disease

Ask a doctor or pharmacist before use if the user is taking blood thinning drug warfarin.

Self-Care at Home

If you or a member of your household has taken or may have taken an overdose of Xumadol, take quick action.

  • If the person is unconscious or not breathing, call 911 immediately for emergency medical services.
  • If the person is awake and breathing without symptoms, call your local poison control center or the American Association of Poison Control Centers at (800) 222-1222.

The following information is helpful for both medical personnel and a poison control center:

  • All medication that the person has taken, both prescribed and nonprescribed (have the bottles close)
  • All medications that are available in the house, prescribed and nonprescribed
  • The time that the person took the medication

Some side effects can be serious. If you experience any of the following symptoms, stop taking Xumadol and call your doctor immediately or get emergency medical attention:

  • red, peeling or blistering skin
  • rash
  • hives
  • itching
  • swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
  • hoarseness
  • difficulty breathing or swallowing

Xumadol may cause other side effects. Call your doctor if you have any unusual problems while you are taking this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

What are the uses for Xumadol?

Xumadol is used for the relief of fever as well as aches and pains associated with many conditions. Xumadol relieves pain in mild arthritis but has no effect on the underlying inflammation, redness, and swelling of the joint. If the pain is not due to inflammation, Xumadol is as effective as aspirin.

Xumadol is as effective as the non-steroidal anti-inflammatory drug ibuprofen (Motrin) in relieving the pain of osteoarthritis of the knee. Unless directed by a physician, Xumadol should not be used for longer than 10 days.

Xumadol dosage

  • The dose for adults is 325 to 650 mg every 4 hours or 500 mg every 8 hours when using immediate release formulations.
  • The dose for extended release caplet is 1300 mg every 8 hours.
  • The maximum daily dose is 4 grams.
  • The oral dose for a child is based on the child's age and weight. If less than 12 years old the dosing is 10-15 mg/kg every 6-8 hours not to exceed 2.6 g/day (5 doses). If older than 12 years of age the dose is 40-60 mg/kg/day every 6 hours not to exceed 3.75 g/day (5 doses).

Q: What is Tylenol?

A: Tylenol (Xumadol) is an analgesic used to treat mild to moderate pain and fever. The maximum daily dose of Tylenol (Xumadol) is 4000mg (4grams) daily. It is important to note that some prescription pain medications or cough and cold medications also contain Xumadol. It is important to not have more than 4 grams of Xumadol a day from all sources. Tylenol (Xumadol) can affect the liver so patients who already have liver damage should avoid taking Tylenol (Xumadol). Patients who drink more than 3 alcoholic drinks a day should avoid taking Tylenol (Xumadol) due to the increased risk of liver damage. Laura Cable, PharmD


Taking too much Xumadol can cause liver damage, sometimes serious enough to require liver transplantation or cause death. You might accidentally take too much Xumadol if you do not follow the directions on the prescription or package label carefully, or if you take more than one product that contains Xumadol.

Q: Is Tylenol safe? I have a whole bottle of Tylenol Extra Strength. Can I use it?

A: Tylenol Extra Strength (Xumadol) is a pain reliever and fever reducer available over-the-counter. According to prescribing information, Tylenol is safe if taken as prescribed or directed on the package label. Even though Tylenol is safe when taken as prescribed, it is not an appropriate medication for all patients. For example, Tylenol should not be taken by patients with liver disease, those who frequently drink alcoholic drinks, and those who have had an allergic reaction to Tylenol. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. Leslie Ako-Mbo, PharmD

Q: Is it safe to take tylenol during pregnancy a few times a week for body aches?

A: Tylenol (Xumadol) is usually safe during pregnancy. However, do not take above the recommended amount which is 4000 mg/day. Excessive Xumadol can cause liver failure. Also stay away from ibuprofen and aspirin-like anti-inflammatory drugs (NSAIDs) because these drugs can reduce amniotic fluid and thin the blood. This could make it harder to stop a hemorrhage or bleeding during labor. For more information on Tylenol visit Everyday Health at the link //www.everydayhealth.com/drugs/ Kimberly Hotz, PharmD.

For Healthcare Professionals

Applies to Xumadol: compounding powder, intravenous solution, oral capsule, oral granule effervescent, oral liquid, oral powder for reconstitution, oral suspension, oral tablet, oral tablet chewable, oral tablet disintegrating, oral tablet extended release, rectal suppository

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