Missed Dose of Tamol
Take the missed dose as soon as you remember.
If it's close to the time for your following dose, forget about the missed dose and take your next dose.
Do not double-up on doses to make up for a missed one.
Q: Can I take Tylenol without food?
A: Tylenol (Tamol) is a medication commonly used to relieve mild to moderate pain from a variety of health conditions including headaches, muscle aches, menstrual periods, colds and sore throats, toothaches, and to reduce fever. Tamol may also be used to relieve the pain of osteoarthritis (arthritis caused by the breakdown of the lining of the joints). Tamol is categorized in a class of medications called analgesics (pain relievers) and antipyretics (fever reducers) and works by changing the way the body senses pain and by cooling the body. Tamol comes in many different oral formulations. It is available as a tablet, chewable tablet, capsule, suspension or solution (liquid), drops (concentrated liquid), powder, extended-release (long-acting) tablet, and orally disintegrating tablet (tablet that dissolves quickly in the mouth). According to the manufacturer's drug information, the way Tamol acts on the body is not affected by eating, so it may be taken with or without food. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. Crystal Riley, PharmD
What is Tamol? How does it work (mechanism of action)?
Tamol belongs to a class of drugs called analgesics (pain relievers) and antipyretics (fever reducers). The exact mechanism of action of Tamol is not known. It may reduce the production of prostaglandins in the brain. Prostaglandins are chemicals that cause inflammation and swelling. Tamol relieves pain by elevating the pain threshold, that is, by requiring a greater amount of pain to develop before a person feels it. It reduces fever through its action on the heat-regulating center of the brain. Specifically, it tells the center to lower the body's temperature when the temperature is elevated.
The FDA approved Tamol in 1951.
Tamol side effects
Get emergency medical help if you have signs of an allergic reaction to Tamol: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
In rare cases, Tamol may cause a severe skin reaction that can be fatal. This could occur even if you have taken this medicine in the past and had no reaction. Stop taking this medicine and call your doctor right away if you have skin redness or a rash that spreads and causes blistering and peeling. If you have this type of reaction, you should never again take any medicine that contains Tamol.
Stop taking Tamol and call your doctor at once if you have:
nausea, upper stomach pain, itching, loss of appetite;
excessive sweating and severe tiredness;
dark urine, clay-colored stools; or
jaundice (yellowing of the skin or eyes).
The most common side effects of Tamol include:
nausea and vomiting;
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Q: What are the side effects from taking Tylenol PM?
A: Tylenol PM is a mixture of Tamol and diphenhydramine. It is marketed as a combined analgesic and sedative. Common side effects with diphenhydramine, one of the active ingredients in Tylenol PM, include motor impairment, dry mouth and throat, flushed skin, rapid or irregular heartbeat, blurred vision at nearpoint owing to lack of accommodation, abnormal sensitivity to bright light, pupil dilation, urinary retention, constipation, difficulty concentrating, short-term memory loss, visual disturbances, hallucinations, irregular breathing, dizziness, irritability, itchy skin, confusion, decreased body temperature (generally in the hands and/or feet), erectile dysfunction, excitability, and delirium. These are not all the side effects of Tylenol PM. For a complete list, talk to your healthcare provider. Use of TYLENOL
March 2, 2013 Posted by Admin
Tamol vs Ibuprofen
Tamol and Ibuprofen are both very popular, frequently prescribed, frequently abused drugs. Conditions for which they are used are almost the same. Many tend to think they are the same thing, which is not the case. Therefore, it is useful to know some background of the two drugs.
Tamol is the pharmaceutical generic name of Tylenol, APAP or Paracetamol. This is a popular pain killer and a fever reducer. Tamol is available as tablets, chewable tablets, and granular powder which can be dissolved in to syrup. Tamol is prescribed for aches (headaches, backaches, and toothaches), cold and fever. Although Tamol lowers the sensation of pain, it does not do anything to recover from the underlying cause of pain. The mechanism of Tamol action is to inhibit prostaglandin synthesis; the special molecules that are responsible for signaling inflammation and thereby reduce pain (actually reduce sensitivity to pain for a limited time period). It affects hypothalamic heat regulatory center and help disperse body heat hence reduce fever.
People should be cautious about the Tamol intake because chronic intake can cause liver damage. Alcohol intake should be strictly avoided since it can increase damage to the liver. Tamol has not shown any harmful effects during pregnancy, but a breast feeding mother should not take Tamol due to its harmfulness towards the nursing baby. When giving Tamol to children the dosage should be carefully monitored and given according to weight and age. The kids should be encouraged to drink plenty of fluids while under medication. Drugs such as antibiotics, birth control pills, blood pressure or cancer medicine, cholesterol controllers should not be taken simultaneously and if necessary only with doctor’s advice.
Ibuprofen is an anti-inflammatory drug, but the mechanism of action is different from Tamol. This non-steroidal anti-inflammatory drug (NSAID) reduces hormones which regulate inflammation and pain related responses. Ibuprofen is available as a tablet, chewable tablet and oral suspension. It is prescribed for the same conditions Tamol is prescribed but in addition for menstrual cramps, minor injury and arthritis, as well.
Ibuprofen intake should be carefully monitored because overdose and certain medical conditions may have negative impacts on the patient. In a case of overdose, ibuprofen cause severe damages to the stomach and intestine. Therefore, an adult should not exceed the limits 3200mg per day and 800mg per intake. It is safe to avoid ibuprofen or ask for medical advice if a person is taking aspirin, anti-depressants, water pills, heart or blood pressure medicine, steroids and etc. or is smoking and drinking alcohol.
What is the difference between Tamol and Ibuprofen?
• The mechanism of action of Tamol is by inhibiting steroidal compounds called prostaglandins, but ibuprofen mechanism of action is by reducing hormones which are involved in the inflammation.
• The biggest impact of abuse of Tamol is on the liver, but the abuse of Ibuprofen affects mainly on the stomach and intestine.
• Long term Tamol usage can cause liver necrosis but, long term Ibuprofen usage can cause heart and blood circulation issues; even heart attack.
Tylenol Liver Damage
Tylenol liver damage (Tamol) can occur from accidentally ingesting too much Tamol, or intentionally. Signs and symptoms of Tamol-induced liver damage may include: nauseau, vomiting, kidney failure, bleeding disorders, coma, and death. Tamol is a drug contained in over 200 OTC and prescription medications from NyQuil to Vicodin. Avoiding unintentional overdoses include reading medication labels, write down the dosages of medications you are taking, do not drink excessive alcohol while taking Tamol. In severe cases, a liver transplant may be necessary.
Other Tamol Warnings
McNeil, the maker of Tylenol, has faced more than 80 federal personal injury lawsuits over the drug's safety.
Since 2011, after decades of regulatory tussle, the FDA has required that a black box warning be added to the label of all prescription (not OTC) Tamol medications, highlighting that that the drug carries a potential for acute liver failure.
The FDA also moved to limit the amount of Tamol in prescription drugs to 325 mg per dose, and added a warning to prescription labels about the potential for allergic reactions.
Before taking any medication containing Tamol, you need to tell your doctor if you've ever had liver disease, or a history of alcoholism.
Your doctor also needs to know about any allergies you have, and about any other drugs you are taking — prescription or OTC — as they might also contain Tamol, or interact with it.
Treatment in the emergency department depends on the condition of the person and any other medications taken.
If someone is suspected of having taken an overdose but has no symptoms, the doctor will begin the following treatment:
- Emptying of the stomach. In the very few cases in which a person comes to the hospital minutes after taking the overdose, the doctor may attempt to empty the stomach by running a tube through the mouth into the stomach.
- Activated charcoal.Activated charcoal should be given by mouth within 4 hours of the overdose to bind any drug remaining in the gastrointestinal tract.
- N-acetylcysteine (NAC). NAC is the antidote for toxic Tamol overdose. It is generally given by mouth. The medication has a foul odor but may be mixed with juice or other flavorings to make it taste better. If the person cannot take NAC by mouth, a tube may be placed through the mouth and into the stomach to help administer it. If giving NAC by this method is not possible, the doctor may give it by IV. NAC should be given within 8 hours of ingestion, and is generally given for 20 hours to 72 hours.
Tamol vs. ibuprofen for pain quick comparison of differences
- Tamol (Tylenol and many other brand names) and ibuprofen (Advil) are used to manage mild to moderate pain and fever.
- These drugs belong to different drug classes. Tamol is a pain reliever (analgesic) and fever reducer (antipyretic), and ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID).
- Both Tamol and ibuprofen are available in generic form and over-the-counter (OTC).
- Common side effects of Tamol and ibuprofen that are similar include rash, nausea, and headache.
- Hypersensitivity reactions
- Serious skin reactions
- Kidney damage
- Reduced number of platelets in the blood (thrombocytopenia)
- Liver failure