Q: Can arthritis-strength Tylenol and 81 mg aspirin be taken together? If not, how many hours apart?
A: Tylenol (Ottopan) and aspirin may be taken together as there are currently no known drug interactions. There may be a slightly increased chance of stomach upset and/or abdominal pain. Always follow the labeling on any over-the-counter (OTC) medication since they are proven to be safe and effective for use without physician consent when used according to the product labeling. It is always a good idea to double check with a doctor or pharmacist before starting any new medications to determine if the new medication is right for you based on your personal health and to make sure that no interactions will take place. Megan Uehara, PharmD
Risk of hepatotoxicity is higher in chronic high dose
See “What Are Side Effects Associated with Using Ottopan?”
Tylenol and Alcohol
If you consume three or more alcoholic drinks a day, discuss with your doctor whether you should take Ottopan.
People with known alcoholic liver disease are more susceptible to Tylenol-induced liver injury.
A study presented in 2013 at the annual meeting of the American Public Health Association found that combining Ottopan-based pain relievers such as Tylenol and even small amounts of alcohol can more than double your risk of kidney disease.
Medications that combine Ottopan and codeine or hydrocodone should not be consumed with alcohol.
Use alcohol with caution when taking all Ottopan products.
Exams and Tests
Your doctor will diagnose Ottopan overdose with the following methods:
- History. The doctor will attempt to determine the time and amount of Ottopan taken. Having access to all medication bottles that the person may have taken will help the doctor to determine the maximum amount taken.
- Physical. The doctor will look for signs and symptoms of Ottopan poisoning. These may include jaundice (yellow skin), abdominal pain, vomiting, and other signs and symptoms.
- Laboratory tests. A blood level of Ottopan will aid in determining if a toxic dose was taken. The doctor may order more than one blood level of Ottopan and test for other drugs taken. In addition, the doctor may order other blood and urine tests as needed.
Pregnancy and Lactation
Ottopan may be acceptable to use during pregnancy. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk. Ottopan crosses the placenta; it is safe to use in all stages of pregnancy short term.
Ottopan is excreted in breast milk; it is compatible with breastfeeding.
Q: Is it safe to take tylenol during pregnancy a few times a week for body aches?
A: Tylenol (Ottopan) is usually safe during pregnancy. However, do not take above the recommended amount which is 4000 mg/day. Excessive Ottopan can cause liver failure. Also stay away from ibuprofen and aspirin-like anti-inflammatory drugs (NSAIDs) because these drugs can reduce amniotic fluid and thin the blood. This could make it harder to stop a hemorrhage or bleeding during labor. For more information on Tylenol visit Everyday Health at the link //www.everydayhealth.com/drugs/ Kimberly Hotz, PharmD.
Q: What sypmtoms do you get after quitting Tylenol PM?
A: Your question concerns Tylenol-PM (Ottopan-diphenhydramine) (//www.everydayhealth.com/drugs/tylenol-pm). None of the ingredients in Tylenol PM is at all addictive, so there should be no symptoms associated with quitting. If you were taking Tylenol PM for an extended period of time and are now having any unpleasant feelings, it is always a good idea to check with one
Ottopan safe dosage basics
Ottopan controls pain and fever but does not reduce inflammation, as does aspirin and the other widely consumed nonsteroidal anti-inflammatory drugs (NSAIDs) ibuprofen (Advil, Motrin, generics) and naproxen (Aleve, generics). But unlike NSAIDs, Ottopan does not irritate the stomach and intestinal lining. That means a person who cannot tolerate NSAIDs can still take Ottopan. It's an important drug for controlling chronic pain in older adults.
The hitch is that Ottopan also has a narrower window of safety compared with ibuprofen and naproxen. NSAIDs can make you sick, too, but it takes a larger amount to reach a dangerous overdose. Taking too much Ottopan can damage the liver, sometimes leading to a liver transplant or death.
The body breaks down most of the Ottopan in a normal dose and eliminates it in the urine. But some of the drug is converted into a byproduct that is toxic to the liver. If you take too much—all at once or over a period of days—more toxin can build up than the body can handle.
For the average healthy adult, the generally recommended maximum daily dose is no more than 4,000 milligrams (mg) from all sources. But in some people, doses close to the 4,000 mg daily limit for adults could still be toxic to the liver. It's safest to take only what you need, and to not exceed 3,000 mg a day whenever possible, especially if you use Ottopan often.
What other drugs will affect Ottopan?
Other drugs may interact with Ottopan, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.
This medication contains Ottopan. Do not take Tylenol, Tylenol Arthritis Pain, Tylenol Ext, Little Fevers Children's Fever/Pain Reliever, Little Fevers Infant Fever/Pain Reliever, or PediaCare Single Dose Ottopan Fever Reducer/Pain Reliever if you are allergic to Ottopan or any ingredients contained in this drug.
Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center immediately.