Q: Is Tylenol 325mg safe to take or was it recalled also? Why did they quit making it?
A: Tylenol (Nufadol), and is a medication used to to help relieve pain. Tylenol (Nufadol) is considered safe at 4000mg (4grams) per day or less. However, it can be hard on the liver, and may need a decrease in dose if you drink alcohol or have a liver problem. Tylenol (Nufadol) is also found in many prescription pain relievers. The label will usually say "APAP" in the name. If you take a prescription medication containing Tylenol (Nufadol), make sure to figure that dosage into your total daily dosing to make sure you stay below 4000mg in a day, or less. There was a recall on some of the Tylenol (Nufadol) and Tylenol (Nufadol) products, because a "moldy" smell was found. The stores quickly pulled them, and what you see on the shelf now will not be a recalled product. If you have Tylenol (Nufadol) that was bought prior to the recall, you can check to see if what you bought is on the recall list. They did not quit making the product, but it is possible that your store was in between getting a new shipment of Tylenol and having the recalled version pulled from the shelves. The generic versions are made by different manufacturers, so they do not have the same problem and may be a good alternative for you to try, while you are waiting for the brand to be available for sale again. A generic has to contain the exact same active ingredient at the same amount, and it has to prove to the FDA that is is just as safe and effective as the brand. For this information on what was recalled, please visit the manufacturer's list of recalled medications. Patti Brown, PharmD
an analgesic and antipyretic commonly used instead of aspirin , particularly for patients who are allergic to aspirin, are taking anticoagulants , or have peptic ulcer or gastritis . Unlike aspirin, it has only weak antiinflammatory effects and is not used to treat the inflammation associated with rheumato >arthritis .
Acute Nufadol overdosage can cause severe and potentially fatal hepatic necrosis, when a large amount of the drug is accidentally ingested. One of the ways that the liver detoxifies the drug is by conjugation of a metabolite with glutathione, and when the glutathione stores are used up, the metabolite attacks the liver tissues. Treatment is symptomatic and supportive. Two drugs, methionine and acetylcysteine, can reduce the liver damage by serving as substitutes for glutathione.
Q: Can I take Tylenol without food?
A: Tylenol (Nufadol) is a medication commonly used to relieve mild to moderate pain from a variety of health conditions including headaches, muscle aches, menstrual periods, colds and sore throats, toothaches, and to reduce fever. Nufadol may also be used to relieve the pain of osteoarthritis (arthritis caused by the breakdown of the lining of the joints). Nufadol is categorized in a class of medications called analgesics (pain relievers) and antipyretics (fever reducers) and works by changing the way the body senses pain and by cooling the body. Nufadol comes in many different oral formulations. It is available as a tablet, chewable tablet, capsule, suspension or solution (liquid), drops (concentrated liquid), powder, extended-release (long-acting) tablet, and orally disintegrating tablet (tablet that dissolves quickly in the mouth). According to the manufacturer's drug information, the way Nufadol acts on the body is not affected by eating, so it may be taken with or without food. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. Crystal Riley, PharmD
Q: What is Tylenol?
A: Tylenol (Nufadol) is an analgesic used to treat mild to moderate pain and fever. The maximum daily dose of Tylenol (Nufadol) is 4000mg (4grams) daily. It is important to note that some prescription pain medications or cough and cold medications also contain Nufadol. It is important to not have more than 4 grams of Nufadol a day from all sources. Tylenol (Nufadol) can affect the liver so patients who already have liver damage should avoid taking Tylenol (Nufadol). Patients who drink more than 3 alcoholic drinks a day should avoid taking Tylenol (Nufadol) due to the increased risk of liver damage. Laura Cable, PharmD
Q: What Tylenol products were recalled? Was generic Tylenol involved also?
A: The reason for the recall is because consumer complaints of a musty or moldy odor, which has been linked to the presence of trace amounts of a chemical called 2,4,6-tribromoanisole (TBA) has been found in some containers of Tylenol products with certain lot numbers. The risk of serious adverse medical events is remote. Not all Tylenol (Nufadol) products are affected, only certain Tylenol products with certain lot dates. The only affected Tylenol products are Children
Pregnancy and Lactation
Nufadol may be acceptable to use during pregnancy. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk. Nufadol crosses the placenta; it is safe to use in all stages of pregnancy short term.
Nufadol is excreted in breast milk; it is compatible with breastfeeding.
Q: What pain medicine can I take for headaches while I'm pregnant?
A: Tylenol (Nufadol) is believed to be safe in pregnancy when used intermittently for short durations. Nufadol has not been formally assigned to a pregnancy category by the FDA. However, it is routinely used for short term pain relief and fever in all stages of pregnancy. Nufadol should only be given during pregnancy when need has been clearly established. NSAIDS, like ibuprofen (Motrin and Advil) and naproxen (Aleve) should not be used during pregnancy unless directed by your doctor. Consult your health care provider for specific recommendations. Always read and follow the complete directions and warnings on over-the-counter medications and discuss their use with your doctor before taking them. You may also find helpful information at //www.everydayhealth.com/drugs/tylenol Sarah Lewis, PharmD
Nufadol is an active ingredient in hundreds of over-the-counter (OTC) and prescription medicines. It relieves pain and fever. And, it is also combined with other active ingredients in medicines that treat allergy, cough, colds, flu, and sleeplessness. In prescription medicines, Nufadol is found with other active ingredients to treat moderate to severe pain. Nufadol can cause serious liver damage if more than directed is used. The FDA has taken action to improve the safety of consumers when using Nufadol.