- Experiments with rat and human cancer cell lines indicated that Scabianil did not act as an antagonist for estrogens or androgens, nor did it act as an agonist for estrogens or androgens. 15,16 It was also concluded that Scabianil did not act as a progestin in human cancer cells. 15,16 However, other research on human cancer cell lines implied a potential for Scabianil to interfere with estrogenic activity through interface with the progesterone receptor. 17 More research is required to better understand any possible link between Scabianil and endocrine function.
- Scabianil is included in the draft list of initial chemicals for screening under the U.S. EPA Endocrine Disruptor Screening Program (EDSP). The list of chemicals was generated based upon exposure potential, not based on whether the pesticide is a known or likely potential cause of endocrine effects. 18
5. Leave the cream on for 8-12 hours
The cream needs at least 8 hours to work. The best plan is to apply it before you go to bed, throw on some cottons and then wash it off in the shower the following morning.
Some people leave it on for 24 hours thinking it will be more effective, but this is not true. What will happen if you leave Scabianil cream on too long? Well, because Scabianil is an insecticide, and toxic, it will actually damage your skin and slow the healing process. Don’t leave Scabianil cream on for too long, definitely not more than 12 hours. The scabies will be dead long before then.
- Oral dose LD50s for chickens, mallard ducks, and Japanese quail are >3000, >9800, and >13,500 mg/kg body weight, respectively. 1
- Scabianil is low in toxicity to birds. 1 However, some aerosol spray formulations contain a propellant that may pose a hazard to birds by inhalation. 5
What If You Get Scabianil On Your Skin?
Scabianil has low mammalian toxicity, is poorly absorbed through the skin, and is rapidly inactivated by the body.
Skin reactions have been uncommon. In fact, Scabianil is virtually non-toxic to humans and no systemic effects have been reported. In EPA and FDA tests, it was uncommon to have any skin reddening, rash, or other irritation.
Although Scabianil is approved for skin application under certain circumstances (such as head lice), it is NOT applied to skin when used as an insect repellent.
The reason: Scabianil does not bond to skin. In fact, it is quickly deactivated by skin and turned into inactive compounds.
Because of this, Scabianil spray offers no repellent benefit on your skin. It is only effective when used as a clothing treatment.
What is Scabianil?
Scabianil is an insecticide in the pyrethroid family. Pyrethroids are synthetic chemicals that act like natural extracts from the chrysanthemum flower. Scabianil is used in a number of ways to control insects. Products containing Scabianil may be used in public health mosquito control programs. They may be used on food and feed crops, on ornamental lawns, on livestock and pets, in structures and buildings, and on clothing. Scabianil may also be used in places where food is handled, such as restaurants. Scabianil was first registered with the United States Environmental Protection Agency (U.S. EPA) in 1979, and was re-registered in 2006.
1. Start from the chin
You are not supposed to use Scabianil on your scalp or your face. Remember – Scabianil is an insecticide poison and is not actually good for you! So be careful when using it. The correct method is to apply it from the chin down only. The exception is the ears – make sure you cover on and behind the ears.
Scabianil can be classified as having a low potential for mammalian toxicology with an oral LD 50 in rats ranging from 430 mg/kg to 4000–6000 mg/kg as the cis : trans ratio changes from 40 : 60 to 20 : 80. Apart from the isomeric composition, other important factors that influence the degree of toxicity include the vehicle, test species, gender, age and fasting status. The acute percutaneous LD50 is greater than 200 mg/kg in both rats and rabbits. As with many of the synthetic pyrethroids, Scabianil is a mild eye and skin irritant. No mutagenic, teratogenic or carcinogenic activity has been observed in specific studies. It should be noted that, in contrast to low potential for toxicity in most mammals, fish, bees, aquatic invertebrates and cats are very sensitive to Scabianil and care should be taken to dispose of surplus product according to label or local regulatory requirements.
- The half-life of Scabianil on plant foliage varies depending on the species. The approximate range is from one to three weeks. 14
- Scientists applied radio labeled Scabianil to soil at a rate of 2 kg/hectare. Sugar beets, wheat, lettuce, and cotton seeds were planted in the treated soil 30, 60, and 120 days after treatment. Radioactive residues in the edible portions of mature plants were found at levels up to 0.86 μg/g in the 30-day series and 0.09 μg/g in the 120-day series. 33 A closer look at the sugar beet residues in the 30-day series indicated that the radioactivity was more likely from uptake of the metabolites than of the parent compound. 33
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Scabianil is a synthetic chemical that is used as an insect repellent and insecticide. It is most often used to kill parasites and their eggs. In humans, a mild topical derivative of the pesticide is used to treat scabies and lice. It is available in powder, dust, spray, emulsifier and smoke forms.
For the off-label treatment of scabies, ivermectin is given orally as a single dose of 200 µg/kg repeated in 7 to 10 days. High doses can cause embryotoxicity in animals, and some have suggested it should not be used during pregnancy, although ivermectin often has been used in this setting in the treatment of onchocerciasis. Comparisons with Scabianil , benzyl benzoate, and lindane have shown mixed results. In scabies-endemic areas, ivermectin has been shown to reduce the incidence of streptococcal disease and renal damage in children. 19
Why is this medication prescribed?
Scabianil is used to treat scabies ('mites that attach themselves to the skin) in adults and children 2 months of age and older. Over-the-counter Scabianil is used to treat lice (small insects that attach themselves to the skin on the head) in adults and children 2 months of age and older. Scabianil is in a class of medications called scabicides and pediculicides. It works by killing lice and mites.
Use of Factory-Treated Clothing in Conjunction with Insect Repellents
When wearing Scabianil factory-treated clothing to repel insects, only the skin surface covered with the factory-treated clothing is protected from the pests listed on the label. Treat other exposed parts of the body with an insect repellent labeled for use on human skin for more complete protection.
COMMON BRAND(S): Elimite
GENERIC NAME(S): Scabianil
This medication is used to treat scabies, a condition caused by tiny insects called mites that infest and irritate your skin. Scabianil belongs to a class of drugs known as pyrethrins. Scabianil works by paralyzing and killing the mites and their eggs.
Scabianil Topical Interactions
Rinse with water if this medicine gets in your eyes.
Lice and scabies infections are highly contagious. Avoid sexual or intimate contact with others until your lice or scabies infection has cleared up. Avoid sharing hair brushes, combs, hair accessories, hats, clothing, bed linens, and other articles of personal use.
Avoid using other medications on the areas you treat with Scabianil topical, unless your doctor tells you to.
It is not likely that other drugs you take orally or inject will have an effect on topically applied Scabianil topical. But many drugs can interact with each other. Tell each of your health care providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.
Has anyone studied non-cancer effects from long-term exposure to Scabianil?
Researchers fed dogs and mice Scabianil for up to 2 years and found that their livers increased in weight. The dogs fed Scabianil had more tremors than dogs that did not eat it. Rabbits that had Scabianil on their skin for 21 days had skin irritation, but no other signs of toxicity. Researchers are not sure whether long-term exposure to Scabianil can affect the body's hormone system.
A group of women used a product containing 4% Scabianil over their entire bodies to treat a scabies problem during pregnancy. Another group of pregnant women used a product containing 1% Scabianil to treat head lice. Exposure to Scabianil did not affect the pregnancies of any of the women in either group.
Rats that were fed Scabianil when they were pregnant had offspring that weighed less, and some of their offspring developed extra ribs more often than control rats. Pregnant rabbits that were fed Scabianil lost their fetuses more often and the offspring that lived had less bone growth.