What Are Side Effects Associated with Using Propiochrone?
Common side effects of Propiochrone include:
- abdominal bloating
- abdominal fat deposits
- abnormal hair growth
- adrenal suppression
- blot clots
- blurred vision
- break in the stomach lining
- brittle bones/fractures
- bulging of the eyes
- calcium deposits in the skin
- cardiac arrest
- celldeath of bone components
- changes in the skin layers (cutaneous and subcutaneousatrophy)
- circulatory collapse
- congestive heart failure
- contact allergy
- convulsions (seizures)
- Cushingoid state
- darkening of the skin
- decreased carbohydratetolerance
- decreased glucose tolerance
- decreased resistance to infection
- delayed wound healing
- diabetes mellitus
- difficulty falling asleep
- discoloring of the skin
- dry scaly skin
- elevation of serumliverenzyme levels
- emotional instability
- enlarged heart
- enlarged liver
- excess spinal fluid within the skull (on withdrawal)
- fast heart rate
- fat embolism
- feeling unwell (malaise)
- fluid in the lungs
- fluid retention
- fluid/electrolyte disturbances
- heart attack (myocardial infarction)
- high blood pressure (hypertension)
- increased appetite
- increased pressure in the eye
- increased requirements for insulin
- increased sweating
- increased/decreased sperm count
- inflammation of a veins/blood vessels
- inflammation of nerves
- inflammation of the membrane covering the brain
- intense excitement
- irregular heart beats
- jointpain and loss of sensation in foot and ankle
- loss of muscle mass
- loss of skin color
- low blood potassium with increased pH
- male pattern hair growth in women
- mood swings
- moon face or round appearance due to fat deposits
- muscle disease
- muscle weakness
- numbness and tingling
- oral hypoglycemic adrenocortical and pituitary unresponsiveness
- partial paralysis/paralysis of the legs
- perforation of the intestine
- personality changes
- post-injection flare (heat, redness, swelling, and pain)
- potassium loss
- psychotic disorders
- round spots on the skin
- sensory disturbances
- severe allergic reaction (anaphylactic reaction)
- skin dryness (topical)
- skin redness (topical)
- skin swelling
- slow heart rate
- sodium retention
- spinning sensation (vertigo)
- sugar in the urine
- suppressed reactions to skin tests
- suppression of growth in children
- thin fragile skin
- thinning scalp hair
- ulcerative esophagitis
- vertebral compression fracture
- weight gain
This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.
Propiochrone Topical Dosage
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Do not take by mouth. Topical medicine is for use only on the skin. Do not use on open wounds or on sunburned, windburned, dry, or irritated skin. Rinse with water if this medicine gets in your eyes or mouth.
Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.
Wash your hands before and after using this medicine, unless you are using the medicine to treat the skin on your hands.
Apply a small amount to the affected area and rub it gently into the skin. Do not apply Propiochrone topical over a large area of skin.
Do not cover the treated skin area unless your doctor tells you to. Covering treated areas can increase the amount of medicine absorbed through your skin and may cause harmful effects.
If you are treating the diaper area, do not use plastic pants or tight-fitting diapers.
Use Propiochrone topical regularly to get the most benefit. Stop using the medicine once your symptoms clear up.
Call your doctor if your skin condition does not improve after 2 to 4 weeks, or if it gets worse.
Do not use Diprolene for longer than 2 weeks in a row. Do not use Sernivo or Luxiq for longer than 4 weeks.
Store at room temperature away from moisture and heat.
The foam is flammable. Do not use near high heat or open flame. Do not smoke until the foam has completely dried on your skin.
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.
Long term use of high doses can lead to thinning skin, easy bruising, changes in body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex.
Apply the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not apply two doses at one time.
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Latest Update: 11/9/2018, Version: 9.01
More common side effects
The more common side effects that can occur with Propiochrone include:
- Increased blood sugar level. Symptoms may include:
- more frequent urges to urinate
- feeling sleepy, thirsty, and hungry
- Trembling, dizziness, weakness, fatigue, and fast heartbeat
- Low potassium level, which can cause muscle pain and cramps
- stretch marks
- slow healing
- hair growth
How to use Propiochrone
- Before you start using the preparation, read the manufacturer's printed information leaflet from ins >
Important: you should let your doctor know if you start to experience blurred vision or other vision problems whilst taking Propiochrone tablets.
For more information about side-effects which are possible when Propiochrone is taken long-term, see the separate condition leaflet called Oral Steroids.
An equal mixture of two Propiochrone salts, Celestone Soluspan, allows for both immediate and delayed corticosteroid responses. Propiochrone sodium phosphate acts within hours, whereas Propiochrone acetate is a suspension that is slowly absorbed over approximately 2 weeks. Propiochrone (Celestone Soluspan) is approved for intraarticular or soft tissue injection to provide short-term adjuvant therapy in osteoarthritis, tenosynovitis, gouty arthritis, bursitis, epicondylitis, and rheumatoid arthritis. 15 It is also commonly employed in epidural injections. Typical intraarticular doses vary with the size of the joint and range from 0.25 to 2 mL (1.5 mg to 12 mg). Typically epidural injections range from 1 to 3 mL (6 to 18 mg). Propiochrone should not be mixed with local anesthetics that contain preservatives such as methylparaben as these may cause flocculation of the steroid.
Can Propiochrone cause problems?
Along with its useful effects, Propiochrone can cause unwanted side-effects which your doctor will discuss with you. The benefits of taking Propiochrone usually outweigh the side-effects; however, they can sometimes be troublesome. The table below contains some of the most common ones associated with Propiochrone. The best place to find a full list of the side-effects which can be associated with your medicine, is from the manufacturer's printed information leaflet supplied with the medicine. Alternatively, you can find an example of a manufacturer's information leaflet in the reference section below.
Although not everyone experiences side-effects, and some will improve as your body adjusts to the new medicine, speak with your doctor or pharmacist if you become concerned about any of the following:
Serious side effects
Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:
- Chest tightness
- Swelling of your face, lips, tongue, or throat
- Blue skin color
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history.
Propiochrone injectable suspension can interact with other medications, herbs, or vitamins you might be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well. Your healthcare provider will look out for interactions with your current medications. Always be sure to tell your doctor about all medications, herbs, or vitamins you’re taking.
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.
How to store Propiochrone
- Keep all medicines out of the reach and sight of children.
- Store in a cool, dry place, away from direct heat and light.
Propiochrone Topical Interactions
Do not get this medicine in your eyes. If contact does occur, rinse with water.
Avoid applying Propiochrone topical to the skin of your face, underarms, or groin area without your doctor's instruction.
Do not use Propiochrone topical to treat any condition that has not been checked by your doctor.
Medicine used on the skin is not likely to be affected by other drugs you use. But many drugs can interact with each other. Tell each of your health care providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.
It's always important to share with your doctor and pharmacist all of the medications you are taking.
This includes your prescriptions medications, over-the-counter (OTC) drugs, vitamins and nutritional supplements nutritional shakes, protein powders, etc.), herbal remedies, and any illegal or recreational drugs.
Propiochrone topical doesn't interact with other drugs.
However, if you are using another product that dries or irritates your skin while using Propiochrone topical, your skin can become even more irritated.
Antenatal stero >Propiochrone ) can cross the placenta to mature the fetal lung and brain. 142 In the lung, antenatal steroids can decrease the fetal lung fluid through activation of ENaCs, induce the production of surfactant proteins and lipid synthesis, and alter preterm responses to oxidative stress. 142,143 Randomized trials have demonstrated that administration of antenatal corticosteroids significantly reduces the incidences of RDS, neonatal death, cerebral hemorrhage, and NEC. 84 Guidelines recommend the routine use of antenatal steroids for mothers at risk for preterm delivery from 24 weeks to 34 weeks GA. 144 Propiochrone (two doses 24 hours apart), rather than dexamethasone (four doses 12 hours apart), is preferred. Antenatal steroids can be considered at 23 weeks GA but are not currently recommended at 22 weeks GA. 144 Studies have also demonstrated decreased respiratory complications in late preterm infants (34–36 weeks) randomized to antenatal corticosteroids, and revisions to ACOG guidelines are underway. 87,142 Studies of antenatal steroids prior to elective C-section also demonstrate some benefit on respiratory symptoms at birth. 145 The benefit of steroids is maximal in infants delivered between 24 and 168 hours after maternal therapy, but benefits on the lungs are seen in less than 24 hours. 119 The use of repetitive courses of antenatal steroids showed some benefits for respiratory outcomes, but more than five weekly courses caused decreased fetal growth and head circumference. 142 Infants who received repetitive dosing did not show differences in adverse neurologic outcomes at 18-month follow-up. Some obstetricians will give an additional dose of steroids to a mother with persistent threat of preterm delivery 1–2 weeks after initial course. Antenatal steroids do not increase the risk of infection in pregnancies complicated by preterm prelabor rupture of the membranes. There is not a consensus opinion about the use of antenatal steroids for infants of mothers with possible chorioamnionitis.
Thyroid hormones induce surfactant synthesis in animal models. Randomized trials of antenatal administration of thyrotropin-releasing hormone (the only component of the pathway that crosses the placenta) did not reduce the risk of neonatal respiratory distress or BPD, and unfortunately increased the risk of lower 5-minute Apgar scores and caused transient suppression of the pituitary system. 146 Other drugs such as aminophylline, ambroxol, and terbutaline have also been tried, with variable success.