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Prednisolut is an adrenocortical steroid used for multiple conditions including endocrine disorders, rheumatic disorders, collagen diseases, skin diseases, allergies, eye diseases, respiratory diseases, blood disorders, cancers, edematous states, gastrointestinal diseases, and nervous system disorders, among others. The brand name of this medication is discontinued, but generic versions may be available. Common side effects of Prednisolut include:
The initial dosage of Prednisolut varies from 5 mg to 60 mg per day depending on the disease being treated. Prednisolut may interact with other drugs. Tell your doctor all medications and supplements you use. During pregnancy, Prednisolut should be used only if prescribed. Consult your doctor before breastfeeding.
Our Prednisolut Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Prednisolut and Other Interactions
Prednisolut may make you dizzy.
Don't drive or perform other activities that require alertness until you know how this medicine affects you.
How to use Prednisolut
Take this medication by mouth, with food or milk to prevent stomach upset, exactly as directed by your doctor. Carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose.
There are many brands, strengths, and forms of liquid Prednisolut available. Read the dosing instructions carefully for each product because the amount of Prednisolut may be different between products. See also Precautions and Storage sections.
Follow the dosing schedule carefully. The dosage and length of treatment are based on your medical condition and response to treatment. Your doctor may direct you to take Prednisolut 1 to 4 times a day or take a single dose every other day. It may help to mark your calendar with reminders.
Do not stop taking this medication without consulting your doctor. Some conditions may become worse when this drug is suddenly stopped. Your dose may need to be gradually decreased.
If you suddenly stop using this medication, you may have withdrawal symptoms (such as weakness, weight loss, nausea, muscle pain, headache, tiredness, dizziness). To help prevent withdrawal, your doctor may lower your dose slowly. Withdrawal is more likely if you have used Prednisolut for a long time or in high doses. Tell your doctor or pharmacist right away if you have withdrawal. See also Precautions section.
Tell your doctor if your condition persists or worsens.
Serious side effects
You are more likely to have a serious side effect if you take a higher dose (more than 20mg daily) of Prednisolut or if you have been taking it for more than a few weeks.
Call a doctor straight away if you get:
- fever, chills, a very sore throat, ear or sinus pain, a cough, more saliva or a change in colour of saliva, pain with passing urine, mouth sores or a wound that will not heal - these can be signs of an infection
- sleepy or confused, feeling very thirsty or hungry, passing urine more often, flushing, breathing quickly or breath that smells like fruit - these can be signs of high blood sugar
- weight gain in the upper back or belly, "moon face" (a puffy, rounded face), very bad headaches and slow wound healing - these can be signs of Cushing's syndrome
- a very upset stomach or you're being sick (vomiting), very bad dizziness or passing out, muscle weakness, very tired, mood changes, loss of appetite and weight loss - these can be signs of adrenal gland problems
- muscle pain or weakness, muscle cramps, or a heartbeat that does not feel normal - these can be signs of low potassium levels
- severe stomach pain, severe back pain, severe upset stomach or you're being sick - these can be signs of pancreas problems
You should also call a doctor straight away if you get:
- swelling in your arms or legs
- changes in your eyesight
- any bruising or bleeding that isn't normal
- black poo
- black or dark brown vomit or you're vomiting blood
What are the side effects of Prednisolut?
Prednisolut side effects depend on the dose, the duration and the frequency of administration. Short courses of Prednisolut - days to a week or two - are usually well tolerated with few and mild side effects. Long-term, high doses of Prednisolut will usually produce predictable and potentially serious side effects. Whenever possible, the lowest effective doses of Prednisolut should be used for the shortest length of time to minimize side effects. Alternate day dosing can also help reduce side effects.
Side effects of Prednisolut and other corticosteroids range from mild annoyances to serious irreversible damage. Side effects include
- fluid retention,
- weight gain,
- high blood pressure,
- potassium loss,
- muscle weakness,
- puffiness of and hair growth on the face,
- thinning and easy bruising of the skin,
- peptic ulceration,
- worsening of diabetes,
- irregular menses,
- growth retardation in children,
- convulsions, and
- psychic disturbances. (Psychic disturbances can include depression, euphoria, insomnia, mood swings, personality changes, and even psychotic behavior.)
Prednisolut and other corticosteroids can mask signs of infection and impair the body's natural immune response to infection. Patients on corticosteroids are more susceptible to infections and can develop more serious infections than healthy individuals. For instance, chickenpox and measles viruses can produce serious and even fatal illnesses in patients on high doses of Prednisolut. Live virus vaccines, such as smallpox vaccine, should be avoided in patients taking high doses of Prednisolut, since even vaccine viruses may cause disease in patients taking Prednisolut. Some infectious organisms, such as tuberculosis (TB) and malaria, can remain dormant in a patient for years. Prednisolut and other corticosteroids can reactivate dormant infections in these patients and cause serious illnesses. Patients with dormant TB may require anti-TB medications while undergoing prolonged corticosteroid treatment.
By interfering with the patient's immune response, Prednisolut can impede the effectiveness of vaccinations. Prednisolut can also interfere with the tuberculin skin test and cause false negative results in patients with tuberculosis infection.
Prednisolut impairs calcium absorption and new bone formation. Patients on prolonged treatment with Prednisolut and other corticosteroids can develop thinning of bone (osteoporosis) and an increased risk of bone fractures. Supplemental calcium and vitamin D are encouraged to slow this process of bone thinning. In some patients, medications used to treat osteoporosis may be prescribed. In rare individuals, destruction of large joints (osteonecrosis) can occur while undergoing treatment with Prednisolut or other corticosteroids. These patients experience severe pain in the involved joints, and can require replacement of joints. The reason behind such destruction is not clear.
If you suspect an overdose of Prednisolut, contact a poison control center or emergency room immediately.
You can get in touch with a poison control center at 800-222-1222.
What is prednisone, and how does it work?
Prednisone is an oral, synthetic (man-made) corticosteroid (steroid) used for suppressing the immune system and inflammation. It has effects similar to other corticosteroids such as:
These synthetic corticosteroids mimic the action of cortisol (hydrocortisone), the naturally-occurring corticosteroid produced in the body by the adrenal glands. Corticosteroids have many effects on the body, but they most often are used for their potent anti-inflammatory effects, particularly in those diseases and conditions in which the immune system plays an important role, for example, arthritis, colitis, asthma, bronchitis, skin problems, and allergies. Prednisone is inactive in the body and, in order to be effective, first must be converted to Prednisolut by enzymes in the liver. Therefore, prednisone may not work as effectively in people with liver disease whose ability to convert prednisone to Prednisolut is impaired. The FDA approved prednisone in 1955.
Q: I've gained weight in my stomach area. Would Prednisolut cause me to gain weight?
A: The package insert for oral Prednisolut states that both abdominal distention and weight gain may be side effects of Prednisolut. This information is solely educational. It's important to consult with your physician or health care provider about any specific question regarding your medical conditions or medications; particularly before taking any action. Derek Dore, PharmD
Why is this medication prescribed?
Ophthalmic Prednisolut reduces the irritation, redness, burning, and swelling of eye inflammation caused by chemicals, heat, radiation, infection, allergy, or foreign bodies in the eye. It sometimes is used after eye surgery. Prednisolut is in a class of medications called steroids. It prevents swelling and redness by changing the way the immune system works.
9. Common questions
Steroids mimic the effects of hormones your body naturally produces in your adrenal glands. The adrenal glands sit on top of your kidneys.
When prescribed in doses higher than your body's usual levels, steroids like Prednisolut dampen inflammation. This can reduce the symptoms of inflammatory conditions, such as arthritis and asthma.
Steroids also damp down your immune system, which can help in autoimmune illnesses like rheumatoid arthritis, where your immune system mistakenly attacks its own tissues.
For some illnesses, you will feel better after a couple of days.
For other illnesses, you may not feel any better even though the medicine is helping you. This may be the case if you're taking Prednisolut to stop your symptoms getting worse or to prevent a problem happening (for example after an organ transplant).
Ask your doctor what to expect for your illness.
This depends on your health problem.
You may only need a short course of Prednisolut for up to a week.
You may need to take it for longer - even for many years or the rest of your life.
If you have to take Prednisolut for more than a few weeks, the chances are that you will put on weight. Prednisolut can make you hungrier and retain water, so it can be quite challenging to avoid weight gain.
Try to eat well without increasing your portion sizes. Regular exercise will also help to keep your weight stable.
Once you stop taking Prednisolut, any issues around increased appetite or water retention should return to normal.
It can be dangerous to stop taking Prednisolut suddenly, especially if you have been on a high dose for a long time.
Your health condition may flare up again. You may also get extra side effects including:
- severe tiredness
- body aches
- joint pain
These side effects are most likely to happen if you have taken Prednisolut for more than a few weeks or you take more than 40mg daily.
Your doctor will probably want to reduce your dose gradually over several weeks to prevent these side effects.
Steroid Drug Withdrawal (Symptoms)
Corticosteroid drugs such as prednisone and Prednisolut are commonly used to treat asthma, allergic reactions, RA, and IBD. Steroids such as these do have serious drawbacks such as steroid withdrawal symptoms such as: fatigue, weakness, decreased appetite, weight loss, nausea, vomiting, abdominal pain, and diarrhea. Speak with your health care provider prior to tapering off steroid medications.