Permetral cream

Permetral

  • Active Ingredient: Permethrin
  • 30gm
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What is Permetral?

The active ingredient of Permetral brand is permethrin. Chemical Name – The Permethrin used is an approximate 1:3 mixture of the cis and trans isomers of the pyrethroid 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylic acid, (3-phenoxyphenyl) methyl ester. Permethrin has a molecular formula of C21H20Cl2O3 and a molecular weight of 391.29. It is a yellow to light orange-brown, low melting solid or viscous liquid. Active Ingredient – Each gram contains Permethrin 50 mg (5%). Inactive Ingredients – Butylated hydroxytoluene, carbomer homopolymer type B, fractionated coconut oil, glycerin, glyceryl monostearate, isopropyl myristate, lanolin alcohols, mineral oil, polyoxyethylene cetyl ethers, purified water, and sodium hydroxide. Formaldehyde 1 mg (0.1%) is added as a preservative.

Used for

Permetral is used to treat diseases such as: Head Lice, Lice, Scabies.

Side Effect

Possible side effects of Permetral include: Burning, itching, numbness, rash, redness, stinging, swelling, or tingling of the scalp; ; ; ; ; .

How to Buy Permetral cream online?

To buy Permetral online - just click on the "Buy Now" button from the top and follow on to our shop. Payment and Order takes a couple of minutes, and all measures are evident. We don't take a medical prescription and also we have many methods of payment. With all the details of fast delivery and confidentiality, then you can read on the relevant pages on the links in the top menu.

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Has anyone studied non-cancer effects from long-term exposure to Permetral?

Researchers fed dogs and mice Permetral for up to 2 years and found that their livers increased in weight. The dogs fed Permetral had more tremors than dogs that did not eat it. Rabbits that had Permetral on their skin for 21 days had skin irritation, but no other signs of toxicity. Researchers are not sure whether long-term exposure to Permetral can affect the body's hormone system.

A group of women used a product containing 4% Permetral over their entire bodies to treat a scabies problem during pregnancy. Another group of pregnant women used a product containing 1% Permetral to treat head lice. Exposure to Permetral did not affect the pregnancies of any of the women in either group.

Rats that were fed Permetral when they were pregnant had offspring that weighed less, and some of their offspring developed extra ribs more often than control rats. Pregnant rabbits that were fed Permetral lost their fetuses more often and the offspring that lived had less bone growth.

Dangers

Although Permetral is useful as a pesticide, Permetral can be dangerous to animals and human beings. It is almost certain to cause major irritation to the skin and eyes. When used injudiciously, Permetral can even cause infertility. It is classified as a non-toxic class II or class III pesticide, the benchmark classification for pesticides that can cause irritation to the skin and eyes. Because of this classification, Permetral is considered a restricted-use pesticide (RUP).

Permetral Topical S >

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have severe burning, stinging, redness, or swelling after applying Permetral topical.

Common side effects may include:

  • mild burning, stinging, itching or mild rash;
  • numbness or tingling where the medicine was applied;
  • headache, dizziness;
  • fever; or
  • stomach pain, nausea, vomiting, diarrhea.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Summary

Permetral topical cream (Elimite, Nix Cream) is a medication prescribed to treat scabies. Drug interactions, side effects, warnings and precautions, dosage, and pregnancy safety information should be reviewed prior to using this medication.

Humans

  • In 1991, the International Agency for Research on Cancer (IARC) classified Permetral as Group 3, "not classifiable as to its carcinogenicity to humans", due to a lack of evidence. 20 More recently, the U.S. EPA has classified Permetral as "likely to be carcinogenic to humans" by ingestion. This rating is based on benign lung and liver tumors found in mice and similar, though inconclusive, evidence in rats, as well as corroborative Structure-Activity Relationships (SAR) information. 2 See the text box on Cancer.

Cancer: Government agencies in the United States and abroad have developed programs to evaluate the potential for a chemical to cause cancer. Testing guidelines and classification systems vary. To learn more about the meaning of various cancer classification descriptors listed in this fact sheet, please visit the appropriate reference, or call NPIC.

Permetral cream 5% (Elimite,Acticin) is an insecticide and works by killing parasites that live on humans,such as the scabies mite and pubic lice. Some info – www.nlm.nih.gov

PACKAGE/LABEL PRINCIPAL DISPLAY PANEL

Permetral Cream, 5%*

For External Use Only. Not for Use In Eyes.

Carcinogenesis, Mutagenesis, Impairment of Fertility

Six carcinogenicity bioassays were evaluated with Permetral, three each in rats and mice. No tumorigenicity was seen in the rat studies. However, species-specific increases in pulmonary adenomas, a common benign tumor of mice of high spontaneous background inc >in vitro and in vivo genetic toxicity studies.

Permetral did not have any adverse effect on reproductive function at a dose of 180mg/kg/day orally in a three-generation rat study.

How to use Lice Treatment Liquid

Apply this medication as soon as possible after it is prescribed. When treating head lice, apply this medication to the hair and scalp only. First wash hair with your regular shampoo, but do not use conditioner. Thoroughly rinse the shampoo out with water, and towel-dry hair. Shake this medication well before using. Cover your eyes with a towel while applying this medication. Completely cover the hair and scalp with the medicine (especially behind the ears and on the hairline at the neck). Avoid getting Permetral in your nose, ears, mouth, vagina, or eyes. If the medicine gets in any of these areas, flush with plenty of water. Do not use more medication than prescribed. Leave the medication on your hair for 10 minutes or as directed by your doctor, then rinse with warm water. Towel-dry your hair and comb out any tangles. A single Permetral treatment can help prevent lice from coming back for 14 days. If eyebrows or eyelashes are infested, do not apply this medication to those areas without first consulting your doctor.

Head lice lay small white eggs (nits) at the base of hair close to the scalp, especially on the hairline at the back of the neck and behind the ears. After treatment with this medication, the infected person should be checked by another person for lice and nits using a magnifying glass and bright light. To remove nits, use the special comb provided, and follow the instructions on the package. After combing, re-check the entire head every day for nits you might have missed. Remove any nits by combing, by hand using a disposable glove, or by cutting them out. If live lice are seen 7 days or more after treatment, a second treatment with Permetral or another drug may be needed.

Inform your doctor if your condition persists or worsens.

Pestic >DEET, Permetral , and organophosphate pesticides are routinely used when U.S. military personnel deploy to more tropical regions in which mosquito or other insect-borne diseases are endemic. While these compounds are used to help prevent diseases that have the potential to disrupt mission operations, they also may produce significant central and peripheral nervous system symptoms when exposure occurs at high doses or at chronic, lower-level exposures.

During the Vietnam War, the U.S. military sprayed herbicides from United States and South Vietnamese military transport planes to defoliate large areas of jungle during the war. These spraying missions started in 1962 (with Agent Purple) and continued for the next 9 years with different combinations of chemicals, including Agent Orange. Each combination of these herbicides contained the long-lived contaminant 2,3,7,8-tetrachlorodibenzo-para-dioxin (TCDD), which has been associated with chloroacne and other more severe health problems, including certain cancers.

Ecological and Environmental Effects

Permetral is known to cause no damage to some kinds of birds, while it can be deadly to others. In birds such as pheasants, Japanese quail and mallard ducks, it is not known to cause any toxicity. However, the effect is almost exactly the opposite in insects and other invertebrates that feed on fish. Inhaling certain quantities can cause extensive and immediate damage to bluefish; catfish; salmon; rainbow trout and bluegill sunfish. Permetral also causes extensive breakdown in soil and groundwater. It is also known to debilitate the nutritive quality of plants, water and vegetables when used in excessive quantities.

Side Effects

Skin irritation, including itching, swelling, and redness, may occur with scabies and temporarily worsen after treatment with Permetral. Mild burning or stinging may also occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

This insecticide can help prevent some mosquito and tick bites. But you must use it properly.

When it comes to preventing bites from mosquitoes and ticks, remember: Summer isn't over yet, so it's important to remain vigilant and stay protected when you head outdoors.

You may think first of insect repellents, such as products containing deet. Using an effective repellent is one of the best ways to keep biting bugs away. It’s also helpful to take steps that safeguard your yard against these pests.

But the Centers for Disease Control and Prevention also recommends another strategy on top of those two: treating your clothing with a pesticide called Permetral. (A repellent keeps bugs away; a pesticide kills them on contact.)

Permetral-treated clothing, first developed by the military a few decades ago, has been available to consumers since 2003. And there are a few ways to use it. You can buy pretreated clothing from various manufacturers (especially those that specialize in outdoor gear). At least one company, Insect Shield, will treat your clothes with Permetral for you, if you mail them in. And you can do it yourself: Permetral spray is available for consumers to buy and apply to their own clothing and gear.

“If it’s used correctly, it works really well,” says Thomas Mather, Ph.D., director of the University of Rhode Island’s Center for Vector-Borne Disease, of treating clothing with Permetral yourself. But the key, he says, is to use it correctly, which not everyone does.

Here, we’ll explain why Permetral-treated clothing might be an option you want to consider for protection against ticks and mosquitoes, how to make sure you get the best protection, and how to treat clothing with Permetral the right way.

DOSAGE AND ADMINISTRATION

Adults and Children

Thoroughly massage Permetral Cream, 5% into the skin from the head to the soles of the feet. Scabies rarely infests the scalp of adults, although the hairline, neck, temple, and forehead may be infested in infants and geriatric patients. Usually 30 grams is sufficient for an average adult. The cream should be removed by washing (shower or bath) after 8 to 14 hours. Infants should be treated on the scalp, temple, and forehead. ONE APPLICATION IS GENERALLY CURATIVE.

Patients may experience persistent pruritus after treatment. This is rarely a sign of treatment failure and is not an indication for retreatment. Demonstrable living mites after 14 days indicate that retreatment is necessary.


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