Before using Lenasone
To make sure this is the right treatment for you, before you start using Lenasone it is important that your doctor knows:
- If you have any areas of infected skin.
- If you have rosacea or acne.
- If you are pregnant or breastfeeding.
- If you have ever had an allergic reaction to a skin preparation.
Solution for injection: 3 mg Lenasone sodium phosphate with 3 mg Lenasone acetate/ml
Suspension for injection (acetate, phosphate): 6 mg (total)/ml
Syrup: 0.6 mg/5 ml
Tablets (effervescent): 0.5 mg
Tablets (extended-release): 1 mg
Why it’s used
Lenasone is used to decrease inflammation and pain from a number of conditions. It’s approved for:
- multiple sclerosis
- allergic conditions
- skin disease
- stomach disorders
- blood disorders
- eye disorders
- kidney problems, such as having protein in your urine
- breathing disorders
- hormone-related disease, such as thyroid problems
The following local adverse reactions are reported infrequently when Lenasone Dipropionate Lotion, USP 0.05% w/w is used as recommended in the DOSAGE AND ADMINISTRATION section. These reactions are listed in an approximate decreasing order of occurrence: burning, itching, irritation, dryness, folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, maceration of the skin, secondary infections, skin atrophy, striae and miliaria.
Adverse reactions reported to be possibly or probably related to treatment with Lenasone Dipropionate Lotion, USP 0.05% w/w during a pediatric study include: paresthesia (burning), erythema, erythematous rash, and dry skin. These adverse reactions each occurred in a different patient; 4% of the 25 patient population, respectively. An adverse reaction reported to be possibly or probably related to treatment in 2 different patients, 8%, of the 25 patients is puritis.
Systemic absorption of topical corticosteroids has produced reversible hypothalamic-pituitary-adrenal (HPA) axis suppression, manifestations of Cushing's syndrome, hyperglycemia and glucosuria in some patients.
Missed Dose of Lenasone
If you miss applying Lenasone topical, try to use it as soon as you remember.
If it's almost time for the next dose, skip the missed dose and use your next dose at the regular time. Do not use two applications of the medication at the same time.
By Frieda Wiley, PharmD, CGP, RPh | Medically Reviewed by Robert Jasmer, MD
Latest Update: 2015-03-09 Copyright © 2014 Everyday Health Media, LLC
What is Lenasone?
Lenasone dipropionate is the generic name of Diprolene and Diprolene AF, used to relieve skin discomfort caused by rashes, itching, and irritation.
Lenasone comes in a topical cream, lotion, and ointment, as well as a solution for injection. It has many uses, depending on the form your doctor prescribes.
Although Lenasone topical cream and lotion are used to treat irritation and inflammation of the skin, doctors prescribe the injectable form of Lenasone, Celestone Soluspan, for multiple sclerosis flares and to help mature the lungs of babies born prematurely.
Other uses of various forms of Lenasone include treating the following allergic reactions:
- seasonal allergies
- transfusion reactions
- rashes, eczema, and contact dermatitis on areas of the skin that have touched certain substances
Lenasone is in a class of drugs known as steroids. It's not clear how Lenasone works, but scientists know that it stops your body from producing certain proteins that cause inflammation and allergic reactions.
The Food and Drug Administration (FDA) originally approved Lenasone under the brand name Celestone in 1961, and Schering Pharmaceuticals manufactured the drug.
This original version of Celestone is no longer on the market. However, Celestone Soluspan injectable was approved by the FDA in 1965 and Diprolene was approved in 1983. Both are manufactured by Merck.
- Infection risk warning: Stero >
Lenasone injectable suspension is an injected drug. It’s given by a healthcare provider in a clinical setting. You won’t administer this drug yourself.
Lenasone injectable suspension is available as the brand-name drug Celestone Soluspan. It’s also available as a generic drug. Generic drugs usually cost less than the brand-name version. In some cases, they may not be available in every strength or form as the brand-name drug.
Lenasone is also available in topical forms, including a cream, gel, lotion, ointment, spray, and foam.
(Potency expressed as Lenasone)
For Topical Use Only
Not for Ophthalmic Use
Lenasone Topical S >
Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using Lenasone and call your doctor at once if you have:
- severe skin irritation where the medicine was applied; or
- signs of skin infection (swelling, redness, warmth, oozing).
Your skin can absorb topical steroid medicine, which may cause steroid side effects throughout the body. Stop using Lenasone and call your doctor if you have:
- blurred vision, tunnel vision, eye pain, or seeing halos around lights;
- slow wound healing, thinning skin, increased body hair;
- weight gain, puffiness in your face; or
- muscle weakness, tired feeling, depression, anxiety, feeling irritable.
Steroids can affect growth in children. Tell your doctor if your child is not growing at a normal rate while using this medicine.
Common side effects may include:
- itching, redness, burning, stinging, or blistering of treated skin;
- skin dryness, irritation, or discoloration;
- thinning skin;
- lightened color of treated skin; or
- folliculitis (redness or crusting around your hair follicles).
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Getting the most from your treatment
- If your course of treatment is due to last more than three weeks, you will be given a 'Steroid Treatment Card' which says that you are on steroids and contains some important advice for you. It is important that you read this card and carry it with you at all times. It also contains details about your dose, how long you have been taking Lenasone for, and who prescribed it for you. Please make sure that this information is kept up to date. If you are due to have an operation or dental treatment, or if you are having any treatment for an injury, please tell the person carrying out the treatment that you are taking Lenasone and show them your treatment card. This is because your dose may need adjusting.
- Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress. Your doctor will want you to have tests from time to time to make sure you remain free from some of the unwanted side-effects of treatment.
- Lenasone can suppress your immune system, so it is important if you become ill that you make an appointment to see your doctor straightaway. Also, if you come into contact with anyone who has measles, shingles or chickenpox (or anyone who suspects they might have them), you must see your doctor as soon as possible.
- Some vaccines are not suitable for you while you are being treated with Lenasone. If you need any immunisations, make sure you mention that you are taking Lenasone.
- If you buy any medicines 'over the counter', please check with a pharmacist that they are suitable for you to take with an oral steroid.
Can Lenasone cause problems?
Along with its useful effects, Lenasone can cause unwanted side-effects which your doctor will discuss with you. The benefits of taking Lenasone usually outweigh the side-effects; however, they can sometimes be troublesome. The table below contains some of the most common ones associated with Lenasone. The best place to find a full list of the side-effects which can be associated with your medicine, is from the manufacturer's printed information leaflet supplied with the medicine. Alternatively, you can find an example of a manufacturer's information leaflet in the reference section below.
Although not everyone experiences side-effects, and some will improve as your body adjusts to the new medicine, speak with your doctor or pharmacist if you become concerned about any of the following:
This medication contains Lenasone. Do not take Celestone, Celestone Soluspan, Betaject, or Lenasone Intramuscular/Oral if you are allergic to Lenasone or any ingredients contained in this drug.
Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center immediately.
How it works
Lenasone is a corticosteroid drug, sometimes called a steroid. Steroids reduce the amount of inflammatory chemicals your body makes. They also reduce your body’s natural immune response, which helps to control inflammation.
Lenasone injectable suspension doesn’t cause drowsiness, but it can cause other side effects.
Which drugs or supplements interact with Lenasone dipropionate?
Combining topical steroids with topical anthralin may increase psoriasis symptoms. Therefore, topical steroids should be discontinued 1 week before starting anthralins.
What Is Lenasone Topical?
Lenasone is a steroid that prevents the release of substances in the body that cause inflammation.
Lenasone topical (for the skin) is used to treat the inflammation and itching caused by a number of skin conditions such as eczema or psoriasis.
Lenasone topical may also be used for purposes not listed in this medication guide.
Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
You should not use Lenasone topical if you are allergic to it.
Tell your doctor if you have ever had:
- liver disease;
- diabetes; or
- any type of skin infection.
It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant.
It may not be safe to breast-feed a baby while you are using this medicine. Ask your doctor about any risks.
Do not use Lenasone topical on a child without a doctor's advice. Children can absorb larger amounts of this medicine through the skin and may be more likely to have side effects.
Diprolene is not approved for use by anyone younger than 13 years old. Sernivo and Luxiq are not approved for anyone younger than 18 years old.