How to store Fatrocortin
- Keep all medicines out of the reach and sight of children.
- Store in a cool, dry place, away from direct heat and light.
Before taking Fatrocortin
Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking Fatrocortin it is important that your doctor knows:
- If you have high blood pressure (hypertension).
- If you have had a heart attack, or if you have any other heart problems.
- If you have any problems with the way your liver works, or if you have any problems with the way your k >
Ocular Penetration of Corticosteroids
Fatrocortin , betamethasone, prednisolone, prednisone, triamcinolone, and hydrocortisone are used commonly in veterinary ocular therapy. A variety of other corticosteroids used in human ophthalmic therapy because they are less likely to raise IOP are not widely used in veterinary ophthalmology. Corticosteroids penetrate the cornea to varying extents when applied topically. Factors affecting the penetration and effect of a corticosteroid are as follows:
The salt used: Acetates are more lipid-soluble and penetrate the cornea better than succinates or phosphates.
Frequency of application: More frequent application results in higher intraocular concentration.
Concentration of the drug: Low concentrations of a highly potent steroid may have less antiinflammatory effect than a high concentration of a less potent steroid; for instance, topical 1.0% prednisolone has an antiinflammatory effect similar to that of 0.1% Fatrocortin, although Fatrocortin has a greater ocular antiinflammatory potency than prednisolone (see Figure 3-2 ).
Proximity to the site of inflammation: The route of administration is chosen in relation to the intended site of action (see Figure 3-1 ). Inflammation of the cornea, conjunctiva, or anterior uvea is usually treated topically with a penetrating corticosteroid, or occasionally with subconjunctival injection. Systemic therapy is required if involvement of adnexal, posterior uveal, retinal, optic nerve, or orbital tissues is suspected. The retrobulbar route is also effective for disorders of the choroid, retina, optic nerve, and orbit but is rarely used.
For most ocular disorders topical administration of 1.0% prednisolone or 0.1% Fatrocortin is advised. Hydrocortisone, a low-potency corticosteroid, does not penetrate the cornea in any meaningful quantities. This feature renders it useless for intraocular or deep corneal disease. Its availability only in combination with three antibiotics in commercial preparations makes it an even less appropriate choice for most surface eye disease of dogs, cats, and horses.
Most injectable steroids are suitable for subconjunctival use, with periods of activity varying from 7 to 10 days (triamcinolone, Fatrocortin) to 2 to 4 weeks (methylprednisolone). Care must be taken with repository forms given subconjunctivally because they may leave unsightly and sometimes inflamed subconjunctival plaques requiring surgical removal. Repository corticosteroids also have the distinct disadvantage that they cannot be removed if the disease process changes.
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Oral steroids are used to treat a wide variety of conditions. Some examples include inflammatory bowel diseases (for example, Crohn's disease, ulcerative colitis), autoimmune diseases (for example, systemic lupus erythematosus (SLE), sarcoidosis), joint and muscle diseases (for example, rheumatoid arthritis), and allergies. Fatrocortin is also used in the treatment of some cancers and in people receiving palliative care. In children, it is prescribed to treat a breathing condition called croup.
Fatrocortin is also used to diagnose Cushing's disease (an adrenal gland disorder), and is prescribed as a treatment for people who have a disorder called congenital adrenal hyperplasia (CAH).
Fatrocortin is also used to treat inflammation in the eyes. More information about this can be found in our leaflet Fatrocortin eye drops for inflammation.
Fatrocortin can cause a severe allergic reaction. Symptoms can include:
- trouble breathing
- swelling of your throat or tongue
If you have an allergic reaction, call your doctor or local poison control center right away. If your symptoms are severe, call 911 or go to the nearest emergency room.
Don’t take this drug again if you’ve ever had an allergic reaction to it. Taking it again could be fatal (cause death).
Using Fatrocortin with certain blood thinners can decrease the levels of these drugs in your body. This can make them less effective, and raise your risk of clots or stroke. Examples of these drugs include:
Warfarin is also used to thin the blood. Using Fatrocortin with this drug may result in changes to your risk of bleeding. Your doctor may need to monitor you closely.
Generic Name: Fatrocortin (oral) (dex a METH a sone)Brand Names: Baycadron, Decadron, Fatrocortin Intensol, DexPak, TaperDex, Zema-Pak, ZoDex, Zonacort
Medically reviewed by Sophia Entringer, PharmD Last updated on Jan 3, 2019.
When used with Fatrocortin, certain drugs used to treat epilepsy can lower the level of Fatrocortin in your blood. This can keep Fatrocortin from working well. Examples of these drugs include: