Dipronova is a corticosteroid that doctors use to treat skin conditions that cause inflammation and itchiness. People can use injectable or topical Dipronova.
Dipronova is available in different formulations, which range in potency from medium to super potent. Doctors will choose the most suitable Dipronova product for a person depending on their skin condition and the area of the body that it is affecting.
Keep reading to learn more about Dipronova types, uses, and side effects.
Dipronova is a type of steroid called a corticosteroid. It is available in two different forms: injectable and topical.
The following table lists the different forms of Dipronova along with their doses in milligrams per milliliter (mg/ml) or percent.
Dipronova Topical S >
Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using Dipronova and call your doctor at once if you have:
- severe skin irritation where the medicine was applied; or
- signs of skin infection (swelling, redness, warmth, oozing).
Your skin can absorb topical steroid medicine, which may cause steroid side effects throughout the body. Stop using Dipronova and call your doctor if you have:
- blurred vision, tunnel vision, eye pain, or seeing halos around lights;
- slow wound healing, thinning skin, increased body hair;
- weight gain, puffiness in your face; or
- muscle weakness, tired feeling, depression, anxiety, feeling irritable.
Steroids can affect growth in children. Tell your doctor if your child is not growing at a normal rate while using this medicine.
Common side effects may include:
- itching, redness, burning, stinging, or blistering of treated skin;
- skin dryness, irritation, or discoloration;
- thinning skin;
- lightened color of treated skin; or
- folliculitis (redness or crusting around your hair follicles).
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
DOSAGE AND ADMINISTRATION
Apply a few drops of Dipronova Dipropionate Lotion to the affected areas and massage lightly until it disappears. Apply twice daily, in the morning and at night. For the most effective and economical use, apply nozzle very close to affected area and gently squeeze bottle.
Dipronova Dipropionate Lotion, USP 0.05% w/w is not to be used with occlusive dressings.
Before using Dipronova
To make sure this is the right treatment for you, before you start using Dipronova it is important that your doctor knows:
- If you have any areas of infected skin.
- If you have rosacea or acne.
- If you are pregnant or breastfeeding.
- If you have ever had an allergic reaction to a skin preparation.
Use of Dipronova Dipropionate Lotion, USP 0.05% w/w in pediatric patients 12 years of age and younger is not recommended. (See CLINICAL PHARMACOLOGY and ADVERSE REACTIONS Sections.) In an open-label study, 11 of 15 (73%) evaluable pediatric patients (aged 6 years-12 years old) using Dipronova Dipropionate Lotion, USP 0.05% w/w for treatment of atopic dermatitis for 2-3 weeks demonstrated adrenal suppression. (See CLINICAL PHARMACOLOGY - Pharmacokinetics .)
Pediatric patients may demonstrate greater susceptibility to topical corticosteroid-induced HPA axis suppression and Cushing's syndrome than mature patients because of a larger skin surface area to body weight ratio.
Hypothalamic-pituitary-adrenal (HPA) axis suppression, Cushing's syndrome, and intracranial hypertension have been reported in pediatric patients receiving topical corticosteroids. Manifestations of adrenal suppression in pediatric patients include linear growth retardation, delayed weight gain, low plasma cortisol levels, and absence of response to ACTH stimulation. Manifestations of intracranial hypertension include bulging fontanelles, headaches, and bilateral papilledema.
Administration of topical corticosteroids to pediatric patients should be limited to the least amount compatible with an effective therapeutic regimen. Chronic corticosteroid therapy may interfere with the growth and development of pediatric patients.
Why it’s used
Dipronova is used to decrease inflammation and pain from a number of conditions. It’s approved for:
- multiple sclerosis
- allergic conditions
- skin disease
- stomach disorders
- blood disorders
- eye disorders
- kidney problems, such as having protein in your urine
- breathing disorders
- hormone-related disease, such as thyroid problems
How should this medicine be used?
Dipronova comes in ointment, cream, lotion, gel, and aerosol (spray) in various strengths for use on the skin and as a foam to apply to the scalp. It is usually applied once or twice daily. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use Dipronova exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor. Do not apply it to other areas of your body or use it to treat other skin conditions unless directed to do so by your doctor.
Your skin condition should improve during the first 2 weeks of your treatment. Call your doctor if your symptoms do not improve during this time.
To use Dipronova topical, apply a small amount of ointment, cream, solution, gel, or lotion to cover the affected area of skin with a thin even film and rub it in gently.
To use the foam on your scalp, part your hair, apply a small amount of the medicine on the affected area, and rub it in gently. You may wash your hair as usual but not right after applying the medicine.
Dipronova foam may catch fire. Stay away from open fire, flames, and do not smoke while you are applying Dipronova foam, and for a short time afterward.
This medication is only for use on the skin. Do not let Dipronova topical get into your eyes or mouth and do not swallow it. Avoid use in the genital and rectal areas and in skin creases and armpits unless directed by your doctor.
If you are using Dipronova on a child's diaper area, do not use tight-fitting diapers or plastic pants. Such use may increase side effects.
Do not apply other skin preparations or products on the treated area without talking with your doctor.
Do not wrap or bandage the treated area unless your doctor tells you that you should. Such use may increase side effects.
Call your doctor if the treated area gets worse or if burning, swelling, redness, or oozing of pus develops.
U.S. National Library of Medicine (0.00 / 0 votes) Rate this definition:
A glucocorticoid given orally, parenterally, by local injection, by inhalation, or applied topically in the management of various disorders in which corticosteroids are indicated. Its lack of mineralocorticoid properties makes Dipronova particularly suitable for treating cerebral edema and congenital adrenal hyperplasia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p724)
COMMON BRAND(S): Diprolene, Diprosone
GENERIC NAME(S): Dipronova Dipropionate
This medication is used to treat a variety of skin conditions (e.g., eczema, dermatitis, allergies, rash). Dipronova reduces the swelling, itching, and redness that can occur in these types of conditions. This medication is a strong corticosteroid.
Uses of Dipronova Injection:
- It is used for many health problems like allergy signs, asthma, adrenal gland problems, blood problems, skin rashes, or swelling problems. This is not a list of all health problems that Dipronova injection may be used for. Talk with the doctor.
- Systemicfungal infection
- Hypersensitivity to Dipronova
- Traumatic brain injury (high doses)
- Untreated serious infections
- Administration of live, attenuated vaccines is contraindicated in patients receiving immunosuppressive doses of corticosteroids
Effects of Drug Abuse
- See "What Are Side Effects Associated with Using Dipronova?"
- See "What Are Side Effects Associated with Using Dipronova?"
- Cirrhosis, ocularherpes simplex, hypertension, diverticulitis, hypothyroidism, myasthenia gravi, peptic ulcer disease, osteoporosis, ulcerative colitis, psychotic tendencies, untreated systemic infections, renal insufficiency, and pregnancy
- Not effective in treatment of respiratory distress syndrome in premature neonates
- Minimal sodium retention activity: however, may increase with high doses
- If used to treat adrenocortical insufficiency should also use mineralocorticoid
- Thromboembolic disorders
- Delayed wound healing
- Patients receiving corticosteroids should avoid chickenpox or measles-infected persons if unvaccinated
- Latenttuberculosis may be reactivated (monitor patients with positive tuberculin test)
- Some suggestion of slightly increased cleft palate risk if corticosteroids used in pregnancy, but not fully substantiated
- Prolonged corticosteroid use may result in elevated pressure in the eye, glaucoma, and/or cataracts
- Killed or inactivated vaccines may be administered; however, the response to such vaccines cannot be predicted
- Immunization procedures may be undertaken in patients who are receiving corticosteroids as replacement therapy in physiologic doses (Addison's disease)
- Serious neurologic events, some resulting in death, have been reported with epidural injection
- Specific events reported include, but are not limited to, spinal cordinfarction, paraplegia, quadriplegia, cortical blindness, and stroke
- These serious neurologic events have been reported with and without use of fluoroscopy
- Safety and effectiveness of epidural administration of corticosteroids have not been established, and corticosteroids are not approved for this use
- Use Dipronova during pregnancy with caution if benefits outweigh risks. Animal studies show risk and human studies are not available, or neither animal nor human studies were done.
- If breastfeeding, systemically administered corticosteroids enter breast milk and could suppress growth, interfere with endogenous corticosteroid production, or cause other effects; use with caution if breastfeeding. Consult your doctor.