Dextasone tablets

Dextasone

  • Active Ingredient: Dexamethasone
  • 1 mg, 0.5 mg
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What is Dextasone?

The active ingredient of Dextasone brand is dexamethasone. Dexamethasone is a steroid that prevents the release of substances in the body that cause inflammation.

Used for

Dextasone is used to treat diseases such as: Addison's Disease, Adrenal Insufficiency, Adrenocortical Insufficiency, Adrenogenital Syndrome, Allergic Rhinitis, Ankylosing Spondylitis, Aphthous Ulcer, Aspiration Pneumonia, Asthma, Asthma, acute, Atopic Dermatitis, Bronchopulmonary Dysplasia, Bursitis, Cerebral Edema, Chorioretinitis, Croup, Cushing's Syndrome, Dermatitis Herpetiformis, Eczema, Epicondylitis, Tennis Elbow, Erythroblastopenia, Evan's Syndrome, Gouty Arthritis, Hemolytic Anemia, Hypercalcemia of Malignancy, Idiopathic Thrombocytopenic Purpura, Inflammatory Bowel Disease, Inflammatory Conditions, Iridocyclitis, Iritis, Juvenile Rheumatoid Arthritis, Keratitis, Leukemia, Loeffler's Syndrome, Lymphoma, Meningitis, Haemophilus influenzae, Meningitis, Listeriosis, Meningitis, Meningococcal, Meningitis, Pneumococcal, Mountain Sickness / Altitude Sickness, Multiple Myeloma, Multiple Sclerosis, Mycosis Fungoides, Nausea/Vomiting, Chemotherapy Induced, Neurosarcoidosis, Pemphigus, Plaque Psoriasis, Psoriasis, Psoriatic Arthritis, Pulmonary Tuberculosis, Rheumatoid Arthritis, Sarcoidosis, Seborrheic Dermatitis, Shock, Synovitis, Systemic Lupus Erythematosus, Thrombocytopenia, Toxic Epidermal Necrolysis, Transverse Myelitis, Tuberculous Meningitis, Ulcerative Colitis, Uveitis, Posterior.

Side Effect

Possible side effects of Dextasone include: backache; muscle pain or tenderness; skin rash; decrease in height; trouble healing; mental depression; agitation.

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For people with certain health conditions

For people with infections. Dextasone may make a systemic fungal infection worse. (Systemic means it affects the whole body, not just one part.) This drug shouldn’t be used if you’re taking medication to treat a systemic fungal infection. Also, Dextasone may hide the signs of a non-fungal infection.

For people with congestive heart failure. Dextasone can increase sodium levels, edema (swelling), and potassium loss. This can make your heart failure worse. Before taking this drug, talk to your doctor about whether it’s safe for you.

For people with high blood pressure. Dextasone can increase sodium levels and edema (swelling). This can increase your blood pressure. Before taking this drug, talk to your doctor about whether it’s safe for you.

For people with peptic ulcers. Dextasone can increase the risk of stomach or intestinal bleeding and ulcers. If you have peptic ulcers or other conditions of the intestines, talk to your doctor about whether this drug is safe for you. Conditions of the intestines include:

  • diverticulitis
  • ulcerative colitis

For people with osteoporosis. Dextasone decreases bone formation. It also increases bone resorption (breakdown of bone). As a result, it raises the risk of osteoporosis (bone thinning). The risk is higher for people already at an increased risk of osteoporosis. These include postmenopausal women.

For people with hyperthyroidism. This drug is removed from the body more quickly than normal. Your doctor may adjust your dose of this drug based on your condition.

For people with eye problems. Long-term use of Dextasone may cause eye problems such as cataracts or glaucoma. Your risk is higher if you already have eye problems such as cataracts, glaucoma, or increased pressure in the eye.

For people with tuberculosis. If you have latent tuberculosis or tuberculin reactivity, Dextasone can re-activate the disease. If you test positive for tuberculosis, talk with your doctor about whether taking this drug is safe for you.

For people with recent history of heart attack. If you’ve recently had a heart attack, use of Dextasone may lead to a tear in your heart muscle. Before you start this drug, be sure your doctor knows you’ve had a recent heart attack.

For people with diabetes. Dextasone can increase blood sugar levels. As a result, your doctor may change the dose of your antidiabetic drugs.

For people with myasthenia gravis (MG). If you have MG, using Dextasone with certain drugs used to treat Alzheimer’s disease can cause severe weakness. Examples of these drugs include memantine, rivastigmine, and donepezil. If possible, wait at least 24 hours after taking these drugs to start Dextasone therapy.

Dextasone Dosage

Doses of Dextasone in eye drop, cream and other forms differ from patient to patient and depend on the condition being treated.

For oral forms, strengths range from 0.5 milligrams (mg) to 6 mg per tablet.

The prescribed dose depends on the medical condition. In general, dosage for oral solutions and tablets are:

  • For adults: 0.75 to 9 mg a day, adjusted as needed.
  • For children: 0.02 to 0.3 mg per kilogram (2.2 pounds) of body weight a day, spread out throughout the day.

The dose for intravenous and intramuscular injections ranges from 0.5 to 9 mg daily, but can be higher or lower.

How to take Dextasone

  • Before starting the treatment, read the manufacturer's printed information leaflet from ins >

Cushing’s syndrome drugs

Aminoglutethimide is used to treat symptoms of Cushing’s syndrome (a disease of the adrenal gland). Using this drug with Dextasone may decrease the amount of Dextasone in your body. This means it may not work as well.

What is Dextasone?

Dextasone is a steroid that prevents the release of substances in the body that cause inflammation.

Dextasone is used to treat many different conditions such as allergic disorders, skin conditions, ulcerative colitis, arthritis, lupus, psoriasis, or breathing disorders.

Dextasone may also be used for purposes not listed in this medication guide.

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Hormones

Taking certain hormones with Dextasone can cause decreased levels of these hormones in your body. Your doctor may have to adjust your dose of either the Dextasone or hormone medications. Examples of these drugs include:

Abstract

Dextasone is a potent, synthetic member of the glucocorticoid class of steroid drugs with pleiotropic effects on multiple signaling pathways, and has been widely used in many disorders during the last 50 years. Recent studies sustain a role of this drug in the heat stress response, increasing the levels of heat-shock proteins, particularly under certain stress conditions. More conflictive is the role of Dextasone on the levels of endoplasmic reticulum chaperons. However, these effects may certainly contribute to explain the therapeutic benefits of Dextasone in cardiac transplant, sepsis, cancer, and other pathologic disorders associated with stress affecting the folding of proteins. In this chapter, we review the methods that can be used to evaluate the effect of Dextasone in the heat stress response both in patients and animal and cellular models.

Interactions

Drug-drug. Barbiturates, phenytoin, rifampin: decreased Dextasone effects

Digoxin: increased risk of digoxin toxicity

Ephedrine: increased Dextasone clearance

Estrogen, hormonal contraceptives: blocking of Dextasone metabolism

Fluoroquinolones: increased risk of tendon rupture

Itraconazole, ketoconazole: increased Dextasone blood level and effects

Live-virus vaccines: decreased antibody response to vaccine, increased risk of adverse reactions

Loop and thiazide diuretics: additive hypokalemia

Nonsteroidal anti-inflammatory drugs: increased risk of GI adverse effects

Somatrem, somatropin: decreased response to these drugs

Drug-diagnostic tests. Calcium, potassium: decreased levels

Cholesterol, glucose: increased levels

Nitroblue tetrazolium test: false-negative result

Drug-herbs. Echinacea: increased immune-stimulating effect

Ginseng: potentiation of immunemodulating response

Drug-behaviors. Alcohol use: increased risk of gastric irritation and GI ulcers

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

An overdose of Dextasone is not expected to produce life threatening symptoms. Long term use of high doses can lead to thinning skin, easy bruising, changes in body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex.


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