Important: you should let your doctor know if you start to experience blurred vision or other vision problems whilst taking Dexazone.
For more information about side-effects which are possible when Dexazone is taken long-term, see the separate leaflet called Oral Steroids.
Michael Stewart, Reviewed by Sid Dajani | Last edited 27 Sep 2019 | Certified by The Information Standard
Dexazone belongs to a class of medicines known as corticosteroids (more commonly called steroids).
Take Dexazone with food.
If your pharmacist gives you a blue 'Steroid Treatment Card', carry this with you at all times.
If you need any medical treatment, make sure the person treating you knows you are taking Dexazone. This is because your dose may need to be increased for a short while.
How to use Dexazone
Take this medication by mouth as directed by your doctor. Take with food or milk to prevent stomach upset. Take this medication by mouth with a full glass of water (8 ounces/240 milliliters) unless your doctor directs you otherwise. If you are using the liquid form of the medication, use a medication-measuring device to carefully measure the prescribed dose. Do not use a household spoon.
If you take this medication once daily, take it in the morning before 9 AM. If you are taking this medication every other day or on another schedule besides a daily one, it may help to mark your calendar with a reminder.
The dosage and length of treatment are based on your medical condition and response to therapy. Your doctor may attempt to reduce your dose slowly from time to time to minimize side effects.
Use this medication regularly in order to get the most benefit from it. To help you remember, take it at the same time(s) each day. It is important to continue taking this medication even if you feel well. Follow the dosing schedule carefully, and take this medication exactly as prescribed.
Do not stop taking this medication without consulting your doctor. Some conditions may become worse when this drug is suddenly stopped. Your dose may need to be gradually decreased.
Inform your doctor if your condition does not improve or worsens.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
An overdose of Dexazone is not expected to produce life threatening symptoms. Long term use of high doses can lead to thinning skin, easy bruising, changes in body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex.
More About Dexazone
Definition from the NCI Drug Dictionary - Detailed scientific definition and other names for this drug.
MedlinePlus Information on Dexazone - A lay language summary of important information about this drug that may include the following:
- warnings about this drug,
- what this drug is used for and how it is used,
- what you should tell your doctor before using this drug,
- what you should know about this drug before using it,
- other drugs that may interact with this drug, and
- possible s >Drugs are often studied to find out if they can help treat or prevent conditions other than the ones they are approved for. This patient information sheet applies only to approved uses of the drug. However, much of the information may also apply to unapproved uses that are being studied.
More common side effects
The more common side effects that can occur with Dexazone oral tablets include:
- stomach upset
- swelling (edema)
- mood changes, such as depression, mood swings, or personality changes
- trouble falling asleep
- low potassium levels (causing symptoms such as tiredness)
- high blood glucose
- high blood pressure
If these effects are mild, they may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, talk to your doctor or pharmacist.
Pharmacology and mechanism of action
Corticostero >Dexazone are approximately 30 times more potent than cortisol. Anti-inflammatory effects are complex, but primarily via inhibition of inflammatory cells and suppression of expression of inflammatory mediators. Use is for treatment of inflammatory and immune-mediated disease. This Dexazone solution differs from Dexazone sodium phosphate in that the sodium phosphate form is water soluble and appropriate for IV administration. Dexazone solution is in a polyethylene glycol vehicle that should not be administered rapidly IV. Dexazone-21-isonicotinate is a suspension registered for IM use. After an injection of 10 mg (total dose) to horses, the half-life was 2.5-5 hours, and the volume of distribution (VDss) was 1.7 L/kg. Oral administration of the same dose had a half-life of 4.3 hours and bioavailability (F) of 61%, with a peak concentration at 1.3 hours. The suspension, (Dexazone-21-isonicotinate) has a slow-release and produces a 39 hour half-life in horses and suppresses cortisol for 140 hours.