Dexamethason injection may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- slowed healing of cuts and bruises
- thin, fragile, or dry skin
- red or purple blotches or lines under the skin
- skin depressions at the injection site
- increased body fat or movement to different areas of your body
- inappropriate happiness
- difficulty falling asleep or staying asleep
- extreme changes in mood changes in personality
- increased sweating
- muscle weakness
- joint pain
- irregular or absent menstrual periods
- increased appetite
- injection site pain or redness
Important: you should let your doctor know if you start to experience blurred vision or other vision problems whilst taking Dexamethason.
For more information about side-effects which are possible when Dexamethason is taken long-term, see the separate leaflet called Oral Steroids.
Why it's used
The Dexamethason oral tablet is used to treat conditions that cause inflammation, conditions related to immune system activity, and hormone deficiency. These conditions include:
- allergic reactions
- rheumatoid arthritis and other rheumatic diseases, including ankylosing spondylitis, psoriatic arthritis, juvenile rheumatoid arthritis, lupus, and acute gouty arthritis
- skin diseases, such as pemphigus, severe erythema multiforme (Stevens-Johnson syndrome), exfoliative dermatitis, bullous dermatitis herpetiformis, severe seborrheic dermatitis, severe psoriasis, or mycosis fungoides
- flare-ups of intestinal disease, such as ulcerative colitis
- flare-ups of multiple sclerosis or myasthenia gravis
- pre-treatment for chemotherapy to reduce inflammation and side effects from cancer medications
- adrenal insufficiency (a condition where the adrenal glands don’t produce enough hormones)
Michael Stewart, Reviewed by Sid Dajani | Last edited 27 Sep 2019 | Certified by The Information Standard
Dexamethason belongs to a class of medicines known as corticosteroids (more commonly called steroids).
Take Dexamethason with food.
If your pharmacist gives you a blue 'Steroid Treatment Card', carry this with you at all times.
If you need any medical treatment, make sure the person treating you knows you are taking Dexamethason. This is because your dose may need to be increased for a short while.
The tablets contain lactose monohydrate, magnesium stearate, starch, sucrose, cosmetic ochre (1 mg), D&C Yellow No.10 (0.5, 4 mg), FD&C Blue No.1(0.75, 1.5 mg), FD&C Green No.3 (4, 6 mg), FD&C Red No.3 (1.5 mg), FD&C Red No.40 (1.5 mg), and FD&C Yellow No.6 (0.5, 4 mg).
The oral solution contains citric acid, disodium edetate, flavoring, glycerin, methylparaben, propylene glycol, propylparaben, sorbitol and water.
The Intensol ™ oral solution contains alcohol, benzoic acid, citric acid, disodium edetate, propylene glycol, and water.
Dexamethason, a synthetic adrenocortical steroid, is a white to practically white, odorless, crystalline powder. It is stable in air. It is practically insoluble in water. The molecular formula is C22H29FO5. The molecular weight is 392.47. It is designated chemically as 9-fluoro-11β, 17, 21-trihydroxy-16α-methylpregna-1, 4-diene, 3, 20-dione and the structural formula is:
What is Dexamethason, and how does it work (mechanism of action)?
Dexamethason is a synthetic (man-made) corticosteroid. Corticosteroids are naturally-occurring chemicals produced by the adrenal glands located above the kidneys. Corticosteroids affect the function of many cells within the body and suppress the immune system. Corticosteroids also block inflammation and are used in a wide variety of inflammatory diseases affecting many organs. The FDA approved Dexamethason in October 1958.
Clinical Trials Accepting Patients
Find Clinical Trials for Dexamethason - Check for trials from NCI's list of cancer clinical trials now accepting patients.
Important: The drug information on this page is meant to be educational. It is not a substitute for medical advice. The information may not cover all possible uses, actions, interactions, or side effects of this drug, or precautions to be taken while using it. Please see your health care professional for more information about your specific medical condition and the use of this drug.
Using nonsteroidal anti-inflammatory drugs (NSAIDs) with Dexamethason raises your risk of stomach upset. Talk with your doctor about whether you can take these drugs together. Examples of NSAIDs include:
- Heart Damage Warning: If you’ve recently had a heart attack, you may be at increased risk for further heart damage from this drug. Before starting this drug, be sure your doctor knows you’ve had a heart attack.
- Infection Warning: Dexamethason can cover up or worsen certain infections. In addition, infections can develop during treatment. Don’t use this drug if you have fungal infections, or a history of parasite infections or tuberculosis. Tell your doctor about any past illnesses or infections.
- Eye Problems Warning: Using Dexamethason for long periods can lead to eye problems such as cataracts or glaucoma. The drug may also cause damage to the optic nerves, or fungal or viral eye infections.
- Measles or Chickenpox Warning: Tell your doctor if you haven’t had chickenpox or measles, or if you haven’t had the vaccines to prevent them. You could have more serious versions of these illnesses if you have them while taking Dexamethason.
Dexamethason is a prescription medication. It’s available as an oral tablet, oral solution, eye drops, and eardrops. It’s also available as an injectable solution or an intraocular solution given after surgery. These last two forms are only given by a healthcare provider.
The Dexamethason tablet is available as the brand-name drug DexPak. It’s also available as a generic drug. Generic drugs usually cost less than the brand-name version. In some cases, they may not be available in all strengths or forms as the brand-name drug.
What is Dexamethason?
Dexamethason is a corticosteroid that prevents the release of substances in the body that cause inflammation.
Dexamethason is used to treat many different inflammatory conditions such as allergic disorders and skin conditions.
Dexamethason is also used to treat ulcerative colitis, arthritis, lupus, psoriasis, and breathing disorders.
Dexamethason may also be used for purposes not listed in this medication guide.
What other information should I know?
Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your body's response to Dexamethason injection.
If you are having any skin tests such as allergy tests or tuberculosis tests, tell the doctor or technician that you are receiving Dexamethason injection.
Before having any laboratory test, tell your doctor and the laboratory personnel that you are using Dexamethason injection.
Do not let anyone else use your medication. Ask your pharmacist any questions you have about refilling your prescription.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
This page contains brief information about Dexamethason and a collection of links to more information about the use of this drug, research results, and ongoing clinical trials.