Your doctor will not prescribe Dexalergin if you have a fungal infection anywhere in your body since the medicine may worsen the infection.
If you are allergic to Dexalergin, you need to alert your doctor.
While taking this medicine, do not get any vaccines without your doctor's permission. The medicine may affect the way the vaccine works.
If someone in your household has had a live virus vaccine (measles, mumps, nasal flu vaccine), you should avoid contact with them while taking Decadron. Ask your doctor for details.
When used with Dexalergin, certain drugs used to treat epilepsy can lower the level of Dexalergin in your blood. This can keep Dexalergin from working well. Examples of these drugs include:
Pharmacology and mechanism of action
Corticostero >Dexalergin are approximately 30 times more potent than cortisol. Anti-inflammatory effects are complex, but primarily via inhibition of inflammatory cells and suppression of expression of inflammatory mediators. Use is for treatment of inflammatory and immune-mediated disease. This Dexalergin solution differs from Dexalergin sodium phosphate in that the sodium phosphate form is water soluble and appropriate for IV administration. Dexalergin solution is in a polyethylene glycol vehicle that should not be administered rapidly IV. Dexalergin-21-isonicotinate is a suspension registered for IM use. After an injection of 10 mg (total dose) to horses, the half-life was 2.5-5 hours, and the volume of distribution (VDss) was 1.7 L/kg. Oral administration of the same dose had a half-life of 4.3 hours and bioavailability (F) of 61%, with a peak concentration at 1.3 hours. The suspension, (Dexalergin-21-isonicotinate) has a slow-release and produces a 39 hour half-life in horses and suppresses cortisol for 140 hours.
You should not use Dexalergin if you have a fungal infection anywhere in your body.
Tell your doctor about all your medical conditions, and all the medicines you are using. There are many other diseases that can be affected by steroid use, and many other medicines that can interact with steroids.
Your dosage may change if you have any unusual stress such as a serious illness, fever or infection, or if you have surgery or a medical emergency. Tell your doctor about any such situation that affects you during treatment.
Dexalergin can weaken your immune system, making it easier for you to get an infection or worsening an infection you already have or have recently had. Tell your doctor about any illness or infection you have had within the past several weeks.
Call your doctor for preventive treatment if you are exposed to chicken pox or measles. These conditions can be serious or even fatal in people who are using steroid medication.
All vaccines may not work as well while you are taking a steroid. Do not receive a "live" vaccine while you are taking this medicine.
Do not stop using Dexalergin suddenly, or you could have unpleasant withdrawal symptoms. Talk to your doctor about how to avoid withdrawal symptoms when stopping the medication.
(listed alphabetically, under each subsection)
The following adverse reactions have been reported with Dexalergin or other corticosteroids:
What are the possible side effects of Dexalergin?
Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
- muscle tightness, weakness, or limp feeling;
- blurred vision, tunnel vision, eye pain, or seeing halos around lights;
- shortness of breath (even with mild exertion), swelling, rapid weight gain;
- severe depression, unusual thoughts or behavior;
- a seizure (convulsions);
- bloody or tarry stools, coughing up blood;
- fast or slow heart rate, weak pulse;
- pancreatitis--severe pain in your upper stomach spreading to your back, nausea and vomiting;
- low potassium level--leg cramps, constipation, irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling; or
- increased blood pressure--severe headache, blurred vision, pounding in your neck or ears, anxiety, nosebleed.
Dexalergin can affect growth in children. Tell your doctor if your child is not growing at a normal rate while using this medicine.
Common side effects may include:
- fluid retention (swelling in your hands or ankles);
- increased appetite;
- mood changes, trouble sleeping;
- skin rash, bruising or discoloration;
- acne, increased sweating, increased hair growth;
- headache, dizziness;
- nausea, vomiting, upset stomach;
- changes in your menstrual periods; or
- changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and waist).
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What Is Dexalergin (Decadron)?
Dexalergin is the generic form of the brand-name drug Decadron, which works on the immune system to help reduce itching, swelling, and inflammation.
It's used to treat a variety of health conditions, including allergies, arthritis, problems with blood or bone marrow, skin problems, and flare-ups of multiple sclerosis (MS).
Dexalergin is a corticosteroid, a class of steroid hormone. The Food and Drug Administration (FDA) approved Decadron in 1958. At that time, Merck & Company made the drug.
Now, several manufacturers offer Dexalergin under various brand names and formulations, including Decadron, Ozurdex, Maxidex, and Baycadron.
It's available to be taken orally or as an intravenous (IV) injection. It also comes in topical skin cream and eye drop forms.