Dermabel cream

Dermabel

  • Active Ingredient: Betamethasone
  • 20gm
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What is Dermabel?

The active ingredient of Dermabel brand is betamethasone. The originating document has been archived. We cannot confirm the completeness, accuracy and currency of the content. It is a white to creamy-white, odorless powder insoluble in water; freely soluble in acetone and in chloroform; sparingly soluble in alcohol. Each gram of Betamethasone Dipropionate Lotion USP (Augmented), 0.05% contains: 0.643 mg Betamethasone dipropionate, USP (equivalent to 0.5 mg Betamethasone) in a colorless, clear to translucent lotion base of purified water, isopropyl alcohol (30%), phosphoric acid used to adjust the pH, hydroxypropyl cellulose, propylene glycol, and monobasic sodium phosphate (monohydrate).

Used for

Dermabel is used to treat diseases such as: Bursitis, Dermatological Disorders, Gouty Arthritis, Inflammatory Conditions, Osteoarthritis.

Side Effect

Possible side effects of Dermabel include: ; ; ; ; ; ; .

How to Buy Dermabel ointment online?

To purchase Dermabel online - just click on the "Buy Now" button from the top and follow on to our shop. Payment and Order takes a few minutes, and all measures are obvious. We do not take a medical prescription and we have many methods of payment. Considering all the details of rapid delivery and confidentiality, you can read on the applicable pages on the hyperlinks from the navigation menu.

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Dermabel and Alcohol

Both alcohol and Dermabel topical can dry the skin, and the combination may dry the skin even more.

You should avoid or limit drinking alcohol while taking Dermabel topical.

How to use Dermabel Dipropionate Cream

Read the Patient Information Leaflet provided by your pharmacist before you start using this medication and each time you get a refill. Use this medication on the skin only. However, do not use it on the face, groin, or underarms or for diaper rash unless directed to do so by your doctor.

Wash and dry your hands. Before applying the medication, clean and dry the affected area. Apply a thin film of the medication to the affected area and gently rub in, usually 1-2 times daily or as directed by your doctor.

Do not cover, bandage, or wrap the area unless directed to do so by your doctor. If your doctor directs you to use this medication in the diaper area on an infant, do not use tight-fitting diapers or plastic pants.

If you are using the lotion form of this medication, shake the bottle well before each dose.

After applying the medication, wash your hands unless you are using this medication to treat the hands. When applying this medication near the eyes, avoid getting it in the eyes as this may worsen or cause glaucoma. Also, avoid getting this medication in the nose or mouth. If you get the medication in these areas, rinse with plenty of water.

Use this medication only for the condition for which it was prescribed. Do not use it for longer than prescribed.

Inform your doctor if your condition persists or worsens after 2 weeks.

What Are Side Effects Associated with Using Dermabel?

Common side effects of Dermabel include:

  • abdominal bloating
  • abdominal fat deposits
  • abnormal hair growth
  • abscess
  • acne
  • adrenal suppression
  • blindness
  • blot clots
  • blurred vision
  • bowel/bladderdysfunction
  • break in the stomach lining
  • brittle bones/fractures
  • bulging of the eyes
  • calcium deposits in the skin
  • cardiac arrest
  • cataracts
  • celldeath of bone components
  • changes in the skin layers (cutaneous and subcutaneousatrophy)
  • circulatory collapse
  • congestive heart failure
  • contact allergy
  • convulsions (seizures)
  • Cushingoid state
  • darkening of the skin
  • decreased carbohydratetolerance
  • decreased glucose tolerance
  • decreased resistance to infection
  • delayed wound healing
  • depression
  • diabetes mellitus
  • difficulty falling asleep
  • discoloring of the skin
  • dizziness
  • dry scaly skin
  • elevation of serumliverenzyme levels
  • emotional instability
  • enlarged heart
  • enlarged liver
  • excess spinal fluid within the skull (on withdrawal)
  • fainting
  • fast heart rate
  • fat embolism
  • feeling unwell (malaise)
  • fluid in the lungs
  • fluid retention
  • fluid/electrolyte disturbances
  • glaucoma
  • headache
  • heart attack (myocardial infarction)
  • hiccups
  • high blood pressure (hypertension)
  • hives
  • increased appetite
  • increased pressure in the eye
  • increased requirements for insulin
  • increased sweating
  • increased/decreased sperm count
  • indigestion
  • inflammation of a veins/blood vessels
  • inflammation of nerves
  • inflammation of the membrane covering the brain
  • intense excitement
  • irregular heart beats
  • itching
  • jointpain and loss of sensation in foot and ankle
  • loss of muscle mass
  • loss of skin color
  • low blood potassium with increased pH
  • male pattern hair growth in women
  • mood swings
  • moon face or round appearance due to fat deposits
  • muscle disease
  • muscle weakness
  • nausea
  • nervousness
  • numbness and tingling
  • oral hypoglycemic adrenocortical and pituitary unresponsiveness
  • pain
  • pancreatitis
  • partial paralysis/paralysis of the legs
  • perforation of the intestine
  • personality changes
  • post-injection flare (heat, redness, swelling, and pain)
  • potassium loss
  • psychotic disorders
  • rash
  • round spots on the skin
  • sensory disturbances
  • severe allergic reaction (anaphylactic reaction)
  • skin dryness (topical)
  • skin redness (topical)
  • skin swelling
  • slow heart rate
  • sodium retention
  • spinning sensation (vertigo)
  • stretchmarks
  • sugar in the urine
  • suppressed reactions to skin tests
  • suppression of growth in children
  • swelling
  • tendonrupture
  • thin fragile skin
  • thinning scalp hair
  • ulcerative esophagitis
  • vertebral compression fracture
  • weight gain

This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.

Pregnancy: Teratogenic effects: Pregnancy Category C

Corticosteroids are generally teratogenic in laboratory animals when administered systemically at relatively low dosage levels.

Dermabel dipropionate has been shown to be teratogenic in rabbits when given by the intramuscular route at doses of 0.05 mg/kg. This dose is approximately 0.03 fold the estimated maximum human dose based on a mg/m 2 comparison. The abnormalities observed included umbilical hernias, cephalocele and cleft palates.

Some corticosteroids have been shown to be teratogenic after dermal application in laboratory animals. There are no adequate and well-controlled studies in pregnant women on teratogenic effects from topically applied corticosteroids. Therefore, topical corticosteroids should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Drugs of this class should not be used extensively on pregnant patients, in large amounts, or for prolonged periods of time.

Pharmacokinetics

The extent of percutaneous absorption of topical corticostero >DOSAGE AND ADMINISTRATION ).

Once absorbed through the skin, topical corticosteroids are handled through pharmacokinetic pathways similar to systemically administered corticosteroids. Corticosteroids are bound to plasma proteins in varying degrees. Corticosteroids are metabolized primarily in the liver and are then excreted by the kidneys. Some of the topical corticosteroids and their metabolites are also excreted into the bile.

Twenty-five pediatric patients ages 6 to 12 years, with atopic dermatitis, were enrolled in an open-label, hypothalamic-pituitary-adrenal (HPA) axis safety study. Dermabel Dipropionate Lotion, USP 0.05% w/w was applied twice daily for 2 to 3 weeks over a mean body surface area of 45% (range 35% to 72%). In 11 of 15 (73%) evaluable patients, adrenal suppression was indicated by either a ≤ 5 mcg/dL pre-stimulation cortisol, or a cosyntropin post-stimulation cortisol ≤ 18 mcg/dL and an increase of DOSAGE AND ADMINISTRATION )

Therefore, patients receiving a large dose of a potent topical steroid applied to a large surface area should be evaluated periodically for evidence of HPA axis suppression by using the urinary-free cortisol and ACTH stimulation tests. If HPA axis suppression is noted, an attempt should be made to withdraw the drug, to reduce the frequency of application, or to substitute a less potent steroid.

Recovery of HPA axis function is generally prompt and complete upon discontinuation of the drug. In an open-label pediatric study of 15 evaluable patients, of the 11 subjects who showed evidence of suppression, 6 subjects were tested 2 weeks after discontinuation of Dermabel Dipropionate Lotion, USP 0.05% w/w, and 4 of the 6 (67%) had complete recovery of HPA axis function. Infrequently, signs and symptoms of steroid withdrawal may occur, requiring supplemental systemic corticosteroids.

Pediatric patients may absorb proportionally larger amounts of topical corticostero >PRECAUTIONS - Pediatric Use .)

If irritation develops, topical corticosteroids should be discontinued and appropriate therapy instituted.

In the presence of dermatological infections, the use of an appropriate antifungal or antibacterial agent should be instituted. If a favorable response does not occur promptly, the corticosteroid should be discontinued until the infection has been adequately controlled.

Pediatric Use

Use of Dermabel Dipropionate Lotion, USP 0.05% w/w in pediatric patients 12 years of age and younger is not recommended. (See CLINICAL PHARMACOLOGY and ADVERSE REACTIONS Sections.) In an open-label study, 11 of 15 (73%) evaluable pediatric patients (aged 6 years-12 years old) using Dermabel Dipropionate Lotion, USP 0.05% w/w for treatment of atopic dermatitis for 2-3 weeks demonstrated adrenal suppression. (See CLINICAL PHARMACOLOGY - Pharmacokinetics .)

Pediatric patients may demonstrate greater susceptibility to topical corticosteroid-induced HPA axis suppression and Cushing's syndrome than mature patients because of a larger skin surface area to body weight ratio.

Hypothalamic-pituitary-adrenal (HPA) axis suppression, Cushing's syndrome, and intracranial hypertension have been reported in pediatric patients receiving topical corticosteroids. Manifestations of adrenal suppression in pediatric patients include linear growth retardation, delayed weight gain, low plasma cortisol levels, and absence of response to ACTH stimulation. Manifestations of intracranial hypertension include bulging fontanelles, headaches, and bilateral papilledema.

Administration of topical corticosteroids to pediatric patients should be limited to the least amount compatible with an effective therapeutic regimen. Chronic corticosteroid therapy may interfere with the growth and development of pediatric patients.

Dermabel belongs to a group of medicines called corticosteroids. It is sometimes referred to simply as an oral steroid.

Important: you should let your doctor know if you start to experience blurred vision or other vision problems whilst taking Dermabel tablets.

For more information about side-effects which are possible when Dermabel is taken long-term, see the separate condition leaflet called Oral Steroids.

What Is Dermabel Topical?

Dermabel is a steroid that prevents the release of substances in the body that cause inflammation.

Dermabel topical (for the skin) is used to treat the inflammation and itching caused by a number of skin conditions such as eczema or psoriasis.

Dermabel topical may also be used for purposes not listed in this medication guide.

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

You should not use Dermabel topical if you are allergic to it.

Tell your doctor if you have ever had:

  • liver disease;
  • diabetes; or
  • any type of skin infection.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant.

It may not be safe to breast-feed a baby while you are using this medicine. Ask your doctor about any risks.

Do not use Dermabel topical on a child without a doctor's advice. Children can absorb larger amounts of this medicine through the skin and may be more likely to have side effects.

Diprolene is not approved for use by anyone younger than 13 years old. Sernivo and Luxiq are not approved for anyone younger than 18 years old.

What Other Drugs Interact with Dermabel?

If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first.

Interactions of Dermabel include:

  • aminoglutethimide
  • amphotericin B injection and potassium-depleting agents
  • antibiotics, specifically macrolide
  • anticholinesterases
  • oral anticoagulants
  • antidiabetics
  • antitubercular drugs
  • cholestyramine
  • cyclosporine
  • digitalis glycosides
  • estrogens, including oral contraceptives
  • hepatic enzyme inducers (barbituarates, phenytoin, carbamazepine, rifampin)
  • ketoconazole
  • nonsteroidal anti-inflammatory agents (NSAIDs)
  • diminished response to vaccines

This information does not contain all possible interactions or adverse effects. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share this information with your doctor and pharmacist. Check with your health care professional or doctor for additional medical advice, or if you have health questions, concerns or for more information about this medicine.

home drugs a-z list Lotrisone(Clotrimazole and Dermabel) side effects drug center

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Lotrisone (clotrimazole and Dermabel) is a combination of an antifungal antibiotic and a topical steroid cream or lotion used to treat or prevent fungal infections of the skin such as athlete's foot, jock itch, and ringworm, and to reduce itching, swelling, and redness of the skin. Side effects of Lotrisone include:

  • itching,
  • skin irritation,
  • dry skin,
  • changes in skin color,
  • increased acne,
  • burning/tingling/stinging skin, or
  • scarring or thinning of the skin.

Apply a thin film dose of Lotrisone cream into the affected skin areas twice a day for one week. Lotrisone may interact with other drugs. Tell your doctor all medications and supplements you use. There are no adequate studies in pregnant women of the teratogenic effects of topically applied corticosteroids, so this drug should be used during pregnancy only if the potential benefit justifies the potential risk. It is not known whether topical administration of corticosteroids could result in sufficient systemic absorption to produce detectable quantities in human milk. Consult your doctor before breastfeeding.

Our Lotrisone Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Can Dermabel cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. You can reduce the risk of side-effects from Dermabel by applying the preparation thinly, no more than twice a day, and applying it to the affected areas only.

What are some things I need to know or do while I take Dermabel Injection?

  • Tell all of your health care providers that you take Dermabel injection. This includes your doctors, nurses, pharmacists, and dentists.
  • Use with care in children. Talk with the doctor.
  • This medicine may affect growth in children and teens in some cases. They may need regular growth checks. Talk with the doctor.
  • Have blood work checked as you have been told by the doctor. Talk with the doctor.
  • Have a bone density test as you have been told by your doctor. Talk with your doctor.
  • Have your eye pressure checked if you are on this medicine for a long time. Talk with your doctor.
  • You may have more chance of getting an infection. Wash hands often. Stay away from people with infections, colds, or flu.
  • Chickenpox and measles can be very bad or even deadly in some people taking steroid drugs like Dermabel injection. Avoid being near anyone with chickenpox or measles if you have not had these health problems before. If you have been exposed to chickenpox or measles, talk with your doctor.
  • This medicine may lower how much natural steroid is in your body. If you have a fever, an infection, surgery, or you are hurt, talk with your doctor. You may need extra doses of oral steroids. These extra steroids will help your body deal with these stresses. Carry a warning card saying that there may be times when you need extra steroids.
  • Long-term use may raise the chance of cataracts or glaucoma. Talk with the doctor.
  • This medicine may cause weak bones (osteoporosis) with long-term use. Talk with your doctor to see if you have a higher chance of weak bones or if you have any questions.
  • Talk with your doctor before getting any vaccines. Use with this medicine may either raise the chance of an infection or make the vaccine not work as well.
  • You may need to lower how much salt is in your diet and take extra potassium. Talk with your doctor.
  • If you have high blood sugar (diabetes), talk with your doctor. This medicine may raise blood sugar.
  • Check your blood sugar as you have been told by your doctor.
  • Talk with your doctor before you drink alcohol.
  • If you are 65 or older, use Dermabel injection with care. You could have more side effects.
  • Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using this medicine while you are pregnant.
  • Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.
  • Very bad health problems have happened when drugs like this one have been given into the spine (epidural). These include paralysis, loss of eyesight, stroke, and sometimes death. It is not known if drugs like this one are safe and effective when given into the spine. These drugs are not approved for this use. Talk with the doctor.
  • Some products have benzyl alcohol. Do not give a product that has benzyl alcohol in it to a newborn or infant. Talk with the doctor to see if this product has benzyl alcohol in it.

Michael Stewart, Reviewed by Sid Dajani | Last edited 27 Sep 2019 | Certified by The Information Standard

Dermabel belongs to a class of medicines known as corticosteroids (more commonly called steroids).

Your pharmacist will give you a blue 'Steroid Treatment Card'. Carry this with you at all times.

If you need any medical treatment, make sure the person treating you knows you are taking Dermabel. This is because your dose may need to be increased for a short while.


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