Can Betasid cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. You can reduce the risk of side-effects from Betasid by applying the preparation thinly, no more than twice a day, and applying it to the affected areas only.
Effects of Stero > Dexamethasone and Betasid have been given to humans and animals in a wide range of dosages, at different gestational ages, and for various indications. While in fetuses with heart block the daily exposure does not exceed 0.05 mg per kg, the treatment is maintained over several weeks. Higher dosages were used in animal studies, for prenatal human pulmonary maturation, and for the postnatal treatment of respiratory distress syndrome. With the caveat that the published data may not be applicable to the fetus with complete atrioventricular block, steroids that cross the placenta have been shown to affect birth weight and the central nervous system with single and repeated prenatal steroid administration. Reduction in birth weight has been seen in sheep, 69 non-human primates, 70 and humans. 60,71,72 The effects on growth are more dramatic with multiple doses. Not unexpectedly, one-quarter of our newborns with isolated heart block were growth-restricted after prolonged transplacental exposure to steroids. Few, if any, other adverse effects on the fetus during the human pregnancy, however, have been documented. Neuroimaging of preterm human infants exposed to a single steroid course for lung maturation suggests a reduced incidence of intraventricular hemorrhage and white matter injury. 73,74 Multiple administration of dexamethasone before or after birth was associated with a reduction in cortical involution and in the cerebral surface area, 75,76 though the clinical significance of these findings is not known. Normal physical and mental development of children and young adults is reported, nonetheless, after prenatal exposure to steroids. 77–80 Similarly, no negative effects on neuro-psychological development and on intelligence were found in a cohort of preschool- and school-age children exposed prenatally to prolonged treatment with dexamethasone. 81
If you suspect an overdose, you should contact a poison control center or emergency room immediately.
You can get in touch with a poison control center at (800) 222-1222.
Why is this medication prescribed?
Betasid topical is used to treat the itching, redness, dryness, crusting, scaling, inflammation, and discomfort of various skin conditions, including psoriasis (a skin disease in which red, scaly patches form on some areas of the body) and eczema (a skin disease that causes the skin to be dry and itchy and to sometimes develop red, scaly rashes). Betasid is in a class of medications called corticosteroids. It works by activating natural substances in the skin to reduce swelling, redness, and itching.
Getting the most from your treatment
- If you are using a moisturiser along with this preparation, apply the moisturiser first. Then wait 10-15 minutes before applying Betasid. This allows time for the moisturiser to be absorbed before the topical corticosteroid is applied. Your skin should be moist but not slippery when you apply Betasid.
- Do not use Betasid on your face unless a skin specialist doctor has said you should. If you have been told to use it on your face, be careful not to get any preparation near your eyes and do not use it for longer periods of time than you have been advised.
- Unless advised to do so by your doctor, do not apply a bandage or dressing to the area being treated, as this will increase absorption of the preparation and increase the risk of side-effects.
- Continue to use Betasid until the flare-up has gone and then stop it. A course of treatment for 7-14 days is often sufficient. If your symptoms have not improved after this time (or if they get worse), speak again with your doctor for further advice. Topical corticosteroids like Betasid should not be used for long periods of time or on large areas of the body.
- After you finish using Betasid, continue to use your moisturiser every day. This will help to prevent a further flare-up. Your doctor may also prescribe a less potent steroid cream for you to use when needed.
- If you are using a preparation of Betasid containing clioquinol, be careful not to let the preparation come into contact with your clothing, as it may stain.
More common side effects
The more common side effects that can occur with Betasid include:
- Increased blood sugar level. Symptoms may include:
- more frequent urges to urinate
- feeling sleepy, thirsty, and hungry
- Trembling, dizziness, weakness, fatigue, and fast heartbeat
- Low potassium level, which can cause muscle pain and cramps
- stretch marks
- slow healing
- hair growth
What Is Betasid Topical?
Betasid is a steroid that prevents the release of substances in the body that cause inflammation.
Betasid topical (for the skin) is used to treat the inflammation and itching caused by a number of skin conditions such as eczema or psoriasis.
Betasid topical may also be used for purposes not listed in this medication guide.
Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
You should not use Betasid topical if you are allergic to it.
Tell your doctor if you have ever had:
- liver disease;
- diabetes; or
- any type of skin infection.
It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant.
It may not be safe to breast-feed a baby while you are using this medicine. Ask your doctor about any risks.
Do not use Betasid topical on a child without a doctor's advice. Children can absorb larger amounts of this medicine through the skin and may be more likely to have side effects.
Diprolene is not approved for use by anyone younger than 13 years old. Sernivo and Luxiq are not approved for anyone younger than 18 years old.
Important: you should let your doctor know if you start to experience blurred vision or other vision problems whilst taking Betasid tablets.
For more information about side-effects which are possible when Betasid is taken long-term, see the separate condition leaflet called Oral Steroids.
What Other Drugs Interact with Betasid?
If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first.
Interactions of Betasid include:
- amphotericin B injection and potassium-depleting agents
- antibiotics, specifically macrolide
- oral anticoagulants
- antitubercular drugs
- digitalis glycosides
- estrogens, including oral contraceptives
- hepatic enzyme inducers (barbituarates, phenytoin, carbamazepine, rifampin)
- nonsteroidal anti-inflammatory agents (NSAIDs)
- diminished response to vaccines
This information does not contain all possible interactions or adverse effects. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share this information with your doctor and pharmacist. Check with your health care professional or doctor for additional medical advice, or if you have health questions, concerns or for more information about this medicine.
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DOSAGE AND ADMINISTRATION
Apply a few drops of Betasid Dipropionate Lotion to the affected areas and massage lightly until it disappears. Apply twice daily, in the morning and at night. For the most effective and economical use, apply nozzle very close to affected area and gently squeeze bottle.
Betasid Dipropionate Lotion, USP 0.05% w/w is not to be used with occlusive dressings.
Betasid Topical Interactions
Do not get this medicine in your eyes. If contact does occur, rinse with water.
Avoid applying Betasid topical to the skin of your face, underarms, or groin area without your doctor's instruction.
Do not use Betasid topical to treat any condition that has not been checked by your doctor.
Medicine used on the skin is not likely to be affected by other drugs you use. But many drugs can interact with each other. Tell each of your health care providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.
Generic Name: Betasid dipropionate Dosage Form: lotion
Medically reviewed by Drugs.com. Last updated on Oct 1, 2018.
What is the dosage for Betasid dipropionate?
- A thin strip of Betasid cream or ointment is applied gently to the affected area once or twice daily.
- A few drops of the lotion is applied to the affected area once or twice daily.
- The lotion should be massaged gently until it disappears.
Large doses and prolonged use of Betasid may cause large amounts to be absorbed into the body and suppress production of cortisol by the adrenal glands. Therefore, the lotion should not be used for longer than two weeks, and not more than 50 ml should be used per week. The augmented cream or ointment should be limited to 45 grams per week. Betasid should not be used with occlusive dressings because occlusive dressings increase absorption into the body.
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Betasid is available in a number of different preparations. It is likely you will be prescribed a cream if the affected areas of your skin are moist or weeping, an ointment if your skin is dry, or a lotion for larger or hairy areas of skin. It is also available as an application for the scalp. Betasid is not generally suitable for children, although short courses of up to two weeks may occasionally be prescribed for a child by a skin specialist doctor.
There are also Betasid preparations available which contain an antibacterial agent (such as clioquinol, neomycin or fusidic acid), or an antifungal agent (such as clotrimazole). You may be prescribed one of these preparations for short-term use if your skin has become infected. They are typically used twice a day for one week only. Some preparations of Betasid also contain an ingredient called salicylic acid. The salicylic acid in these formulations can help the steroid to be absorbed more effectively by your skin, but these are also only prescribed for short periods of time.
The extent of percutaneous absorption of topical corticostero >DOSAGE AND ADMINISTRATION ).
Once absorbed through the skin, topical corticosteroids are handled through pharmacokinetic pathways similar to systemically administered corticosteroids. Corticosteroids are bound to plasma proteins in varying degrees. Corticosteroids are metabolized primarily in the liver and are then excreted by the kidneys. Some of the topical corticosteroids and their metabolites are also excreted into the bile.
Twenty-five pediatric patients ages 6 to 12 years, with atopic dermatitis, were enrolled in an open-label, hypothalamic-pituitary-adrenal (HPA) axis safety study. Betasid Dipropionate Lotion, USP 0.05% w/w was applied twice daily for 2 to 3 weeks over a mean body surface area of 45% (range 35% to 72%). In 11 of 15 (73%) evaluable patients, adrenal suppression was indicated by either a ≤ 5 mcg/dL pre-stimulation cortisol, or a cosyntropin post-stimulation cortisol ≤ 18 mcg/dL and an increase of DOSAGE AND ADMINISTRATION )
Therefore, patients receiving a large dose of a potent topical steroid applied to a large surface area should be evaluated periodically for evidence of HPA axis suppression by using the urinary-free cortisol and ACTH stimulation tests. If HPA axis suppression is noted, an attempt should be made to withdraw the drug, to reduce the frequency of application, or to substitute a less potent steroid.
Recovery of HPA axis function is generally prompt and complete upon discontinuation of the drug. In an open-label pediatric study of 15 evaluable patients, of the 11 subjects who showed evidence of suppression, 6 subjects were tested 2 weeks after discontinuation of Betasid Dipropionate Lotion, USP 0.05% w/w, and 4 of the 6 (67%) had complete recovery of HPA axis function. Infrequently, signs and symptoms of steroid withdrawal may occur, requiring supplemental systemic corticosteroids.
Pediatric patients may absorb proportionally larger amounts of topical corticostero >PRECAUTIONS - Pediatric Use .)
If irritation develops, topical corticosteroids should be discontinued and appropriate therapy instituted.
In the presence of dermatological infections, the use of an appropriate antifungal or antibacterial agent should be instituted. If a favorable response does not occur promptly, the corticosteroid should be discontinued until the infection has been adequately controlled.