U.S. National Library of Medicine (0.00 / 0 votes) Rate this definition:
A glucocorticoid given orally, parenterally, by local injection, by inhalation, or applied topically in the management of various disorders in which corticosteroids are indicated. Its lack of mineralocorticoid properties makes Betabiotic particularly suitable for treating cerebral edema and congenital adrenal hyperplasia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p724)
More common side effects
The more common side effects that can occur with Betabiotic include:
• Give as a single daily dose before 9:00 A.M.
• Give oral dose with food or milk.
• Administer I.M. injection deep into gluteal muscle (may cause tissue atrophy).
☞ Don't give Betabiotic acetate I.V.
• Be aware that typical suspension dosage ranges from one-third to one-half of oral dosage given q 12 hours.
☞ To avoid adrenal insufficiency, taper dosage slowly and under close supervision when discontinuing.
• Know that drug may be given with other immunosuppressants.
Which drugs or supplements interact with Betabiotic dipropionate?
Combining topical steroids with topical anthralin may increase psoriasis symptoms. Therefore, topical steroids should be discontinued 1 week before starting anthralins.
What is the dosage for Betabiotic dipropionate?
- A thin strip of Betabiotic cream or ointment is applied gently to the affected area once or twice daily.
- A few drops of the lotion is applied to the affected area once or twice daily.
- The lotion should be massaged gently until it disappears.
Large doses and prolonged use of Betabiotic may cause large amounts to be absorbed into the body and suppress production of cortisol by the adrenal glands. Therefore, the lotion should not be used for longer than two weeks, and not more than 50 ml should be used per week. The augmented cream or ointment should be limited to 45 grams per week. Betabiotic should not be used with occlusive dressings because occlusive dressings increase absorption into the body.
Indications and dosages
➣ Inflammatory, allergic, hematologic, neoplastic, autoimmune, and respiratory diseases; prevention of organ rejection after transplantation surgery
Adults: 0.6 to 7.2 mg/day P.O. as single daily dose or in divided doses; or up to 9 mg I.M. of Betabiotic acetate and sodium phosphate suspension.
➣ Bursitis or tenosynovitis
Adults: 1 ml of suspension intrabursally
➣ Rheumatoid arthritis or osteoarthritis
Adults: 0.5 to 2 ml of suspension intra-articularly
Information for Patients
This information is intended to aid in the safe and effective use of this medication. It is not a disclosure of all possible adverse or intended effects.
Patients using topical corticosteroids should receive the following information and instructions:
1. This medication is to be used as directed by the physician. It is for external use only. Avoid contact with the eyes.
2. Patients should be advised not to use this medication for any disorder other than that for which it was prescribed.
3. The treated skin area should not be bandaged or otherwise covered or wrapped as to be occlusive. (See DOSAGE AND ADMINISTRATION .)
4. Patients should report any signs of local adverse reactions.
5. Other corticosteroid-containing products should not be used with Betabiotic Dipropionate Lotion, USP 0.05% w/w without first talking to your physician.
Before using Betabiotic
To make sure this is the right treatment for you, before you start using Betabiotic it is important that your doctor knows:
- If you have any areas of infected skin.
- If you have rosacea or acne.
- If you are pregnant or breastfeeding.
- If you have ever had an allergic reaction to a skin preparation.
COMMON BRAND(S): Diprolene, Diprosone
GENERIC NAME(S): Betabiotic Dipropionate
This medication is used to treat a variety of skin conditions (e.g., eczema, dermatitis, allergies, rash). Betabiotic reduces the swelling, itching, and redness that can occur in these types of conditions. This medication is a strong corticosteroid.
The corticosteroids are a class of compounds comprising steroid hormones, secreted by the adrenal cortex and their synthetic analogs. In pharmacologic doses corticosteroids are used primarily for their anti-inflammatory and/or immunosuppressive effects.
Topical corticosteroids, such as Betabiotic dipropionate, are effective in the treatment of corticosteroid-responsive dermatoses primarily because of their anti-inflammatory, antipruritic, and vasoconstrictive actions. However, while the physiologic, pharmacologic, and clinical effects of the corticosteroids are well known, the exact mechanisms of their actions in each disease are uncertain. Betabiotic dipropionate, a corticosteroid, has been shown to have topical (dermatologic) and systemic pharmacologic and metabolic effects characteristic of this class of drugs.
Before taking Betabiotic
Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking Betabiotic it is important that your doctor knows:
- If you have high blood pressure (hypertension).
- If you have had a heart attack, or if you have any other heart problems.
- If you have any problems with the way your liver works, or if you have any problems with the way your k >
Freebase (0.00 / 0 votes) Rate this definition:
Betabiotic is a potent glucocorticoid steroid with anti-inflammatory and immunosuppressive properties. Unlike other drugs with these effects, Betabiotic does not cause water retention. It is applied as a topical cream, ointment, foam, lotion or gel to treat itching. Betabiotic sodium phosphate is sometimes prescribed as an intramuscular injection for itching from various ailments, including allergic reactions to poison ivy and similar plants.