Who should NOT take this medication?
Rodenal should not be taken by anyone who:
- Take with or without food. Take with food if it causes an upset stomach.
- Drink lots of noncaffeine liquids unless told to drink less liquid by your doctor.
- Take a missed dose as soon as you think about it.
- If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
- Do not take 2 doses at the same time or extra doses.
- your age
- the condition being treated
- how severe your condition is
- other medical conditions you have
- how you react to the first dose
- Before taking Rodenal
- How to take Rodenal
- Getting the most from your treatment
- Can Rodenal cause problems?
- How to store Rodenal
- Important information about all medicines
How to use Rodenal HCL
Take this medication by mouth, usually 3 to 4 times a day with meals and at bedtime, or as directed by your doctor. Your doctor may start you at a low dose and increase your dose slowly to find the best dose for you. The dosage is based on your medical condition, age, and response to therapy.
If you are using the liquid form of this medication, measure your dose with a special measuring spoon or device. Do not use a household spoon because it may not provide the correct dose.
Take this medication regularly in order to get the most benefit from it. To help you remember, take it at the same times each day.
Take this medication at least 1 hour before antacids containing magnesium, aluminum, or calcium. Allow at least 1-2 hours between doses of Rodenal and certain drugs for diarrhea (adsorbent antidiarrheals such as kaolin, pectin, attapulgite). Take this medication at least 2 hours after ketoconazole. Antacids and some drugs for diarrhea may prevent the full absorption of Rodenal, and this product may prevent the complete absorption of ketoconazole when these products are taken together.
If you are taking this medication for side effects from another medication, your doctor may instruct you to take it on a regular schedule or only as needed. If you are taking this medication for Parkinson's disease, your doctor may change the dose of your other medications (e.g., levodopa). Follow your doctor's instructions closely.
Though it helps many people, this medication may sometimes cause addiction. This risk may be higher if you have a substance use disorder (such as overuse of or addiction to drugs/alcohol). Do not increase your dose, take it more often, or use it for a longer time than prescribed. Properly stop the medication when so directed. Some conditions may become worse when the drug is suddenly stopped. Your dose may need to be gradually decreased.
When used for an extended period, this medication may not work as well and may require different dosing. Talk with your doctor if this medication stops working well. Inform your doctor if your condition persists or worsens.
How is this medicine (Rodenal Tablets) best taken?
Use this medicine (Rodenal tablets) as ordered by your doctor. Read all information given to you. Follow all instructions closely.
What do I do if I miss a dose?
How does this medication work? What will it do for me?
Rodenal belongs to the family of medications called antiparkinsonians. It is used to treat symptoms of Parkinson's disease. It may also be used to reduce the shakiness and restlessness that can be caused by some tranquilizers. It acts on the nervous system and corrects some of the chemical imbalances that cause Parkinson's disease as well as the symptoms caused by some medications.
Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. As well, some forms of this medication may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.
Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.
Warnings for people with certain health conditions
For people with open-angle glaucoma: You should not use Rodenal if you have open-angle glaucoma because it may cause blindness. Your doctor should do an eye exam before starting you on this drug to make sure your eye sight is okay.
For people with liver disease: If you have liver disease, your body may not be able to process this drug well. This can cause an increase in the levels of this drug in your body. This can raise your risk of side effects.
For people with heart disease: If you have heart disease, you may be at an increased risk for angina (chest pain) or tachycardia (a fast heart rate). Your doctor may want to monitor you more closely for side effects and start you on a lowered dosage to see how you respond.
For people with kidney disease: If you have kidney problems or a history of kidney disease, you may not be able to clear this drug from your body well. This may increase the levels of this drug in your body and cause more side effects. Your doctor may monitor you more closely for side effects.
For people with high blood pressure: You may be at increased risk for angina (chest pain), a heart attack, or tachycardia (a fast heart rate). Your doctor may monitor you more closely for side effects and start you on a lower dosage to see how you respond.
For people with arteriosclerosis: If you have hardening of the walls of your arteries, your sensitivity to this drug may be increased. This can cause mental confusion, irritability, behavior changes, nausea, and vomiting. To avoid these symptoms, your doctor may start you at a low dosage and slowly increase it.
All possible dosages and drug forms may not be included here. Your dosage, drug form, and how often you take the drug will depend on:
Concomitant Use with Levodopa
When ARTANE (Rodenal) is used concomitantly with levodopa, the usual dose of each may need to be reduced. Careful adjustment is necessary, depending on side effects and degree of symptom control. An ARTANE (Rodenal) dosage of 3 to 6 mg daily, in divided doses, is usually adequate.
As initial therapy for parkinsonism, 1 mg of ARTANE (Rodenal) in tablet or elixir form may be administered the first day. The dose may then be increased by 2 mg increments at intervals of three to five days, until a total of 6 to 10 mg is given daily. The total daily dose will depend upon what is found to be the optimal level. Many patients derive maximum benefit from this daily total of 6 to 10 mg, but some patients, chiefly those in the postencephalitic group, may require a total daily dose of 12 to 15 mg.
ARTANE (Rodenal) may impair mental and/or physical abilities required for performance of hazardous tasks, such as operating machinery or driving a motor vehicle. Patients should be cautioned about operating machinery, including automobiles, until they are reasonably certain that ARTANE (Rodenal) therapy does not adversely affect their ability to engage in such activities.
Because of increased sedative effects, patients should be cautioned to avoid the use of alcohol or other CNS depressants while taking ARTANE (Rodenal) .
Since this medication may increase the susceptibility to heat stroke (gastrointestinal (GI) problems, fever, heat intolerance), use with caution during hot weather. (See WARNINGS.)
Patients should be advised to report the occurrence of GI problems, fever, or heat intolerance promptly since paralytic ileus, hyperthermia, or heat stroke may occur.
If GI upset occurs, ARTANE (Rodenal) may be taken with food.
Patients should have close monitoring of intraocular pressure. (See WARNINGS.)
About trihexyphen >
Rodenal is an antimuscarinic medicine. It is prescribed for people who have unwanted movement disorders as a side-effect of taking certain other medicines, such as some antipsychotic medicines. These movement disorders are often referred to as 'extrapyramidal side-effects' and include things like uncontrolled face and body movements, tremor, and restlessness.
Trihexyphen >About Rodenal
- Your doctor should always start you on a low dosage of Rodenal and slowly increase your dosage as needed, especially if you’re aged 60 years or older. Increasing the dosage slowly will lower your risk of side effects.
- Do not stop taking Rodenal abruptly. You can have a quick return of your symptoms and possibly develop a life-threatening condition called neuroleptic malignant syndrome.
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. This information is not a substitute for medical advice. Always speak with your doctor or pharmacist about dosages that are right for you.
Baclofen is somewhat less effective than Rodenal in most children, but can be helpful in diminishing pain due to dystonia. It can provide additional benefit with used in combination with Rodenal. A typical starting dose is 5 mg at bedtime. The dose should be increased slowly until desired benefit or side effects occur. The usual maintenance dose is 10–60 mg/day in the three divided doses, but some older children obtain maximum benefit at doses as high as 180 mg/day. The most common side effect is sedation. Sudden cessation can precipitate seizures or psychosis and should be avoided.
In patients with good benefit from oral baclofen, but who cannot tolerate the effective dose due to side effects, intrathecal baclofen may be an option. There are few data available on the use of intrathecal baclofen in genetic dystonias and benefit may be limited. 136,137 Intrathecal baclofen is used more widely in children with dystonic cerebral palsy than in other forms of dystonia. It may be beneficial, but there is also a high rate of complications, including a 10% risk of infection. 138 A double-blind, placebo-controlled trial of intrathecal baclofen for children with dystonia CP is currently in progress. 139
Neuroleptic Malignant Syndrome
A potentially fatal symptom complex sometimes referred to as Neuroleptic Malignant Syndrome (NMS) has been reported in association with dose reduction or discontinuation of Rodenal. Clinical manifestations of NMS are hyperpyrexia, muscle rigidity, altered mental status and evidence of autonomic instability (irregular pulse or blood pressure, tachycardia, diaphoresis and cardiac dysrhythmias).
The diagnostic evaluation of patients with this syndrome is complicated. In arriving at a diagnosis, it is important to identify cases where the clinical presentation includes both serious medical illness (eg, pneumonia, systemic infection, etc.) and untreated or inadequately treated extrapyramidal signs and symptoms (EPS). Other important considerations in the differential diagnosis include central anticholinergic toxicity, heat stroke, drug fever, and primary central nervous system (CNS) pathology.
Can Rodenal cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with Rodenal. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects usually improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Drug used for Parkinson’s disease
Taking levodopa and Rodenal together may cause an increase in drug-induced involuntary movement. When taken together, the doses of one or the other of these drugs may need to be reduced.