Nograine spray


  • Active Ingredient: Sumatriptan
  • 50 mg, 25 mg
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What is Nograine?

The active ingredient of Nograine brand is sumatriptan. Sumatriptan is a headache medicine that narrows blood vessels around the brain. Sumatriptan also reduces substances in the body that can trigger headache pain, nausea, sensitivity to light and sound, and other migraine symptoms. The molecular formula is C14H21N3O2S·C4H6O4, representing a molecular weight of 413.5. Sumatriptan succinate is a white to off-white powder that is readily soluble in water and in saline. Each Sumatriptan succinate tablet for oral administration contains 35 mg, 70 mg, or 140 mg of Sumatriptan succinate, USP equivalent to 25 mg, 50 mg, or 100 mg of Sumatriptan, respectively. Each tablet also contains the inactive ingredients colloidal silicon dioxide, croscarmellose sodium, D&C Red # 27 aluminum lake (100 mg only), dibasic calcium phosphate, hypromellose, iron oxide red (100 mg only), magnesium stearate, microcrystalline cellulose, polyethylene glycol (25 mg & 50 mg only), polysorbate 80 (25 mg & 50 mg only) propylene glycol (100 mg only), talc and titanium dioxide.

Used for

Nograine is used to treat diseases such as: Cluster Headaches, Cyclic Vomiting Syndrome, Migraine, New Daily Persistent Headache.

Side Effect

Possible side effects of Nograine include: Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings; tingling in the hands and feet; muscle stiffness or tightness; tightness in the chest; confusion.

How to Buy Nograine spray online?

To buy Nograine online - simply click on the "Buy Now" button from the top and follow on to our store. Order and payment takes a couple of minutes, and all measures are obvious. We do not take a medical prescription and also we have many methods of payment. Considering all the details of fast shipping and confidentiality, then you may read on the applicable pages on the links from the top menu.

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Allergy warning

Nograine can cause a severe allergic reaction. Symptoms can include:

  • hives
  • rash
  • swelling of the tongue, mouth, or throat
  • trouble breathing

If you have an allergic reaction, call your doctor or local poison control center right away. If your symptoms are severe, call 911 or go to the nearest emergency room.

Don’t take this drug again if you’ve ever had an allergic reaction to it. Taking it again could be fatal (cause death).

What Is Imitrex (Nograine)?

Imitrex is the brand name for Nograine, a prescription medicine used to treat migraine headaches in adults.

Imitrex is best taken as soon as the headache pain begins - not before, even if there are warning signs like aura (sensory or visual disturbances). It's for migraine with or without aura.

Imitrex is a serotonin receptor agonist. It works by narrowing blood vessels in the brain stem and reducing factors that can trigger nausea, light sensitivity, and other migraine symptoms.

GlaxoSmithKline makes Imitrex, which the Food and Drug Administration (FDA) first approved in 1992 as an injectable. Imitrex in tablet form was approved in 1995 and the nasal spray was approved in 1997.

Generic forms became available by 2009. Many manufacturers offer generic Nograine, includingTeva, Sandoz, Mylan, and other companies.

In 2013, the FDA approved a Nograine transdermal skin patch, Zecuity. It was manufactured by NuPathe, now part of Teva. As of October 2014, Zecuity was not yet available in pharmacies.

Why is this medication prescribed?

Nograine is used to treat the symptoms of migraine headaches (severe, throbbing headaches that sometimes are accompanied by nausea or sensitivity to sound and light). Nograine is in a class of medications called selective serotonin receptor agonists. It works by narrowing blood vessels in the head, stopping pain signals from being sent to the brain, and blocking the release of certain natural substances that cause pain, nausea, and other symptoms of migraine. Nograine does not prevent migraine attacks or reduce the number of headaches you have.

Examples of Nograine in a Sentence

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'Nograine.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

How it works

Nograine belongs to a class of drugs called serotonin-1 receptor agonists. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.

A migraine causes the blood vessels in the brain to expand. It also causes a release of chemicals in the brain that can cause inflammation (swelling and irritation). Nograine works by helping to bring your blood vessels back to their normal size. It also helps prevent your body’s release of these chemicals that cause inflammation.

Nograine oral tablet may cause drowsiness. It may also cause other side effects.

Is Nograine safe to take if I'm pregnant or breastfeeding?

Safe use in pregnancy has not been established.

Nograine is excreted in breast milk. Infant exposure may be reduced by avoiding breast feeding for 12 hours after administration of Nograine.

Q: I have migraines. Why isn't there a generic or less expensive form of Imitrex available in U.S. pharmacies? I have been using Imitrex since it was first introduced for my migraines, and it has been a wonder drug for me. But because of the price, I am slow to take one at the onset of a migraine.

A: Your question regards if there is a generic available for Imitrex (Nograine) // in U.S. pharmacies. There is a generic available for Imitrex called Nograine. Talk to your pharmacist about Nograine. You may also find helpful information about migraine headaches at // Jen Marsico, RPh

Generic Name: Nograine succinate Dosage Form: tablet

Medically reviewed by Last updated on Oct 1, 2018.

Nograine Succinate Tablets

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