Melodol tablets


  • Active Ingredient: Meloxicam
  • 15 mg, 7.5 mg
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What is Melodol?

The active ingredient of Melodol brand is meloxicam. Meloxicam is a nonsteroidal anti-inflammatory drug (NSAID). Meloxicam works by reducing hormones that cause inflammation and pain in the body.

Used for

Melodol is used to treat diseases such as: Fibromyalgia, Inflammatory Conditions, Juvenile Rheumatoid Arthritis, Osteoarthritis, Rheumatoid Arthritis, Tendonitis.

Side Effect

Possible side effects of Melodol include: increased sensitivity of the skin to sunlight; anxiety; itching, redness, or other discoloration of the skin; trouble sleeping; discouragement; dilated neck veins; skin blisters; cough.

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Exacerbation of Asthma Related to Aspirin Sensitivity

A subpopulation of patients with asthma may have aspirin-sensitive asthma which

may include chronic rhinosinusitis complicated by nasal polyps; severe, potentially fatal bronchospasm; and/or intolerance to aspirin and other NSA >see Contraindications (4) ]. When Melodol is used in patients with preexisting asthma (without known aspirin sensitivity), monitor patients for changes in the signs and symptoms of asthma.

Rated Melodol for Osteoarthritis Report

So I have had herniated disks on and off for 15 new doc gave me cortisone injections in the spaces between the vertibrae. and perscribed me I take it and get diarrhea, and don't know for sure if it's because of the med. take it the second day. get even worse diarrhea and it make me dizzy as hell. I'm not going for a 3rd day.


Melodol, an oxicam derivative, is a member of the enolic acid group of nonsteroidal anti-inflammatory drugs (NSAIDs). Each light yellow colored tablet contains Melodol 7.5 mg and light yellow colored tablet contains Melodol 15 mg for oral administration. It is chemically designated as 4-hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-2-H-1,2-benzothiazine-3-carboxamide-1,1-dioxide. The molecular weight is 351.4. Its empirical formula is C14H13N3O4S2 and it has the following structural formula.

COMMON BRAND(S): Mobic, Vivlodex


OTHER NAME(S): Melodol Tablet

Nonsteroidal anti-inflammatory drugs (including Melodol) may rarely increase the risk of a heart attack or stroke. This effect can happen at any time while taking this drug but is more likely if you take it for a long time. The risk may be greater if you have heart disease or increased risk for heart disease (for example, due to smoking, family history of heart disease, or conditions such as high blood pressure or diabetes). Do not take this drug right before or after heart bypass surgery (CABG).

Also, this drug may rarely cause serious (rarely fatal) bleeding from the stomach or intestines. This effect can occur without warning symptoms at any time while taking this drug. Older adults may be at higher risk for this effect. (See also Precautions and Drug Interactions sections.)

Stop taking Melodol and get medical help right away if you notice any of the following rare but serious side effects: bloody or black/tarry stools, persistent stomach/abdominal pain, vomit that looks like coffee grounds, chest/jaw/left arm pain, shortness of breath, unusual sweating, weakness on one side of the body, sudden vision changes, slurred speech.

Talk with your doctor or pharmacist about the risks and benefits of treatment with this medication.

Melodol is used to treat arthritis. It reduces pain, swelling, and stiffness of the joints. Melodol is known as a nonsteroidal anti-inflammatory drug (NSAID).

If you are treating a chronic condition such as arthritis, ask your doctor about non-drug treatments and/or using other medications to treat your pain. See also Warning section.

Hepatic Impairment

No dose adjustment is necessary in patients with mild to moderate hepatic impairment. Patients with severe hepatic impairment have not been adequately studied. Since Melodol is significantly metabolized in the liver and hepatotoxicity may occur, use Melodol with caution in patients with hepatic impairment .


Symptoms following acute NSA >see Warnings and Precautions (5.1, 5.2, 5.4, 5.6) ].

Manage patients with symptomatic and supportive care following an NSAID overdosage. There are no specific antidotes. Consider emesis and/or activated charcoal (60 to 100 grams in adults, 1 to 2 grams per kg of body weight in pediatric patients) and/or osmotic cathartic in symptomatic patients seen within four hours of ingestion or in patients with a large overdosage (5 to 10 times the recommended dosage). Forced diuresis, alkalinization of urine, hemodialysis, or hemoperfusion may not be useful due to high protein binding.

There is limited experience with Melodol overdosage. Cholestyramine is known to accelerate the clearance of Melodol. Accelerated removal of Melodol by 4 g oral doses of cholestyramine given three times a day was demonstrated in a clinical trial. Administration of cholestyramine may be useful following an overdosage.

For additional information about overdosage treatment, call a poison control center (1-800-222-1222).

Melodol Dosage

Generally speaking, the daily recommended dose of Melodol is 7.5 mg.

Your doctor may increase the dosage to 15 mg.

Melodol should be taken exactly as prescribed, at the lowest dose possible for your treatment and for the shortest time needed.

Take Melodol with a glass of water. Swallow the pill whole; don't chew it or let it melt/dissolve in your mouth.

Take Melodol with or without food. Taking it with food can help prevent an upset stomach.

Also, wait at least 30 minutes after taking Melodol before lying down to help prevent an upset stomach.

  • Tobacco smoking

You should speak to your doctor or pharmacist before using other cold, allergy, or pain medication, since drugs similar to Melodol exist in many combination medicines.

If you're taking Melodol, carefully check the labels of other products you're taking to see if they also contain an NSAID such as aspirin, ibuprofen, ketoprofen, or naproxen.

Taking too many NSAIDs can result in serious side effects, such as stomach ulcers, gastrointestinal bleeding, or cardiovascular problems.

Skin Reactions

NSAIDs, including Melodol tablets, can cause serious skin adverse events such as exfoliative dermatitis, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis (TEN), which can be fatal. These serious events may occur without warning. Patients should be informed about the signs and symptoms of serious skin manifestations and use of the drug should be discontinued at the first appearance of skin rash or any other sign of hypersensitivity.

Side Effects of Melodol

Melodol side effects includes most common stomach upset, nausea, dizziness, and/or diarrhea. If any of these effects shown, ask your doctor or pharmacist promptly.

Keep in mind that your doctor has endorsed this medicine since the person has judged that the benefit to you is more prominent than the risk of side effects. Numerous individuals utilizing this Melodol don’t serious side effects.

Melodol can increase your blood pressure. Check your blood pressure routinely and tell your doctor if the outcomes are high.

Consult your doctor immediately if you see any serious side effects, including simple wounding/bleeding, severe headache, mental changes, abrupt weight gain, swelling of the hands/feet, indications of kidney issues, (for example, change in the amount of pee), unexplained hardened neck, unordinary tiredness.

This medication may once in a while cause serious liver sickness. Get therapeutic help immediately in the event that you have any side effects of liver harm, including dull pee, diligent nausea/spewing/loss of appetite, stomach/stomach torment, yellowing eyes/skin.

An intense unfavorably allergic reaction to this medication is rare. Be that as it may, get medicinal help immediately if you see any symptoms of a serious allergic reaction, including rash, tingling/swelling (particularly of the face/tongue/throat), extreme tipsiness, trouble in breathing.

This is certainly not a total rundown of possible side effects. If you see different impacts not listed above, contact your specialist or drug specialist.

Nonsteroidal anti-inflammatory drugs (NSAIDs)

Melodol is an NSAID. Combining it with other NSAIDs may increase your risk of side effects, such as stomach bleeding or ulcers. Examples of NSAIDs include:

  • aspirin
  • ibuprofen
  • naproxen
  • etodolac
  • diclofenac
  • fenoprofen
  • ketoprofen
  • tolmetin
  • indomethacin

The Melodol dosage your doctor prescribes will depend on several factors. These include:

  • the type and severity of the condition you’re using Melodol to treat
  • your age
  • the form of Melodol you take
  • other medical conditions you may have, such as kidney damage

Typically, your doctor will start you on a low dosage and adjust it over time to reach the dosage that’s right for you. They’ll ultimately prescribe the smallest dosage that provides the desired effect.

The following information describes dosages that are commonly used or recommended. However, be sure to take the dosage your doctor prescribes for you. Your doctor will determine the best dosage to suit your needs.


Prospective studies show that up to 7% of patients taking Melodol experience at least transient serum aminotransferase elevations. These may resolve even with drug continuation. Aminotransferase elevations >3 fold elevated occur in 1% of patients. Clinically apparent liver injury with jaundice from Melodol is rare and only individual case reports have been published. The latency to onset in reported cases was short (1-5 weeks) and both cholestatic and hepatocellular patterns of enzyme elevations were described. Immunoallergic features are usually not prominent and autoantibodies are rare, although a single case report of autoimmune hepatitis apparently triggered by Melodol therapy has been published. Recovery is typically rapid once Melodol is stopped. Melodol is rarely mentioned as an etiologic agent in large case series on drug induced liver injury and acute liver failure.

Melodol side effects

Get emergency medical help if you have signs of an allergic reaction to Melodol: sneezing, runny or stuffy nose; wheezing or trouble breathing; hives; swelling of your face, lips, tongue, or throat.

Get emergency medical help if you have signs of a heart attack or stroke: chest pain spreading to your jaw or shoulder, sudden numbness or weakness on one side of the body, slurred speech, feeling short of breath.

Stop using Melodol and call your doctor at once if you have:

the first sign of any skin rash, no matter how mild;

shortness of breath (even with mild exertion);

swelling or rapid weight gain;

signs of stomach bleeding - bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds;

liver problems - nausea, upper stomach pain, itching, tired feeling, flu-like symptoms, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);

kidney problems - little or no urinating, painful or difficult urination, swelling in your feet or ankles, feeling tired or short of breath;

low red blood cells (anemia) - pale skin, feeling light-headed or short of breath, rapid heart rate, trouble concentrating; or

severe skin reaction - fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.

Common Melodol side effects may include:

upset stomach, nausea, vomiting, heartburn;

diarrhea, constipation, gas;

cold symptoms, flu symptoms.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


Carefully consider the potential benefits and risks of Melodol tablets and other treatment options before deciding to use Melodol tablets. Use the lowest effective dose for the shortest duration consistent with individual patient treatment goals (see WARNINGS).

Melodol tablet is indicated for relief of the signs and symptoms of osteoarthritis and rheumatoid arthritis.

Forms and strengths

Generic: Melodol

  • Form: oral tablet
  • Strengths: 7.5 mg, 15 mg

Brand: Mobic

  • Form: oral tablet
  • Strengths: 7.5 mg, 15 mg

Brand: Qmiiz ODT

  • Form: orally disintegrating tablet
  • Strengths: 7.5 mg, 15 mg

Anticoagulant/blood thinner

Taking warfarin with Melodol increases your risk of stomach bleeding.

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