Cinie tablets

Cinie

  • Active Ingredient: Sumatriptan
  • 50 mg, 25 mg
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What is Cinie?

The active ingredient of Cinie brand is sumatriptan. Sumatriptan is a headache medicine that narrows blood vessels around the brain. Sumatriptan also reduces substances in the body that can trigger headache pain, nausea, sensitivity to light and sound, and other migraine symptoms. The molecular formula is C14H21N3O2S·C4H6O4, representing a molecular weight of 413.5. Sumatriptan succinate is a white to off-white powder that is readily soluble in water and in saline. Each Sumatriptan succinate tablet for oral administration contains 35 mg, 70 mg, or 140 mg of Sumatriptan succinate, USP equivalent to 25 mg, 50 mg, or 100 mg of Sumatriptan, respectively. Each tablet also contains the inactive ingredients colloidal silicon dioxide, croscarmellose sodium, D&C Red # 27 aluminum lake (100 mg only), dibasic calcium phosphate, hypromellose, iron oxide red (100 mg only), magnesium stearate, microcrystalline cellulose, polyethylene glycol (25 mg & 50 mg only), polysorbate 80 (25 mg & 50 mg only) propylene glycol (100 mg only), talc and titanium dioxide.

Used for

Cinie is used to treat diseases such as: Cluster Headaches, Cyclic Vomiting Syndrome, Migraine, New Daily Persistent Headache.

Side Effect

Possible side effects of Cinie include: back, leg, or stomach pains; tightness in the chest; puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue; confusion; chest tightness or heaviness; pinpoint red spots on the skin; transdermal patch device assisted; nightmares.

How to Buy Cinie spray online?

To buy Cinie online - simply click on the "Buy Now" button from the top and follow on to our shop. Payment and Order takes a few minutes, and all steps are evident. We do not require a medical prescription plus also we have many methods of payment. Considering each detail of rapid shipping and confidentiality, then you may read on the applicable pages on the links from the top menu.

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Dose Adjustments

Elderly: -Dose selection for the older patient should be cautious, generally starting at the lower end of the dosing range due to a greater frequency of hepatic, renal, cardiac impairment as well as presence of concomitant disease or drug therapy.

For patients initiating therapy with subcutaneous injections: -If migraine returns after an initial dose of subcutaneous injection, additional oral doses may be given up to 100 mg orally per day, with at least a 2 hour interval between tablet doses.

For patients initiating therapy with Xsail(R) Breath Powdered Delivery Device: -If migraine returns after an initial intranasal dose, 1 dose of another Cinie product may be given as long as at least 2 hours has elapsed since intranasal administration.

Dosage Modifications

Mild to moderate hepatic impairment: Oral not to exceed 50 mg/dose; no dosage adjustments necessary if administered SC (use with caution)

Severe hepatic impairment: Contraindicated

Enter a drug name and Cinie

Lactation

Cinie is excreted in human milk following subcutaneous administration; there are no data on effects of Cinie on breastfed infant or effects of Cinie on milk production; developmental and health benefits of breastfeeding should be considered along with mother’s clinical need for injection and any potential adverse effects on breastfed infant from Cinie or from underlying maternal condition

Infant exposure to Cinie can be minimized by avoiding breastfeeding for 12 hr after therapy

For patients using Cinie injection:

This medicine comes with patient directions. Read them carefully before using the medicine, and check with your health care professional if you have any questions.

Your health care professional will teach you how to inject yourself with the medicine. Be sure to follow the directions carefully. Check with your health care professional if you have any problems using this medicine.

After you have finished injecting the medicine, be sure to follow the precautions in the patient directions about safely discarding the empty cartridge and the needle. Always return the empty cartridge and needle to their container before discarding them. Do not throw away the autoinjector unit, because refills are available.

Serious side effects

Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:

  • Heart attack. Symptoms can include:
    • chest pain that spreads to your shoulder or arm
    • excessive sweating
    • dizziness
    • weakness
    • shortness of breath
  • severe chest pain
  • fast heart rate
  • irregular heart beat
  • palpitations (feeling like your heart is skipping beats)
  • tightness
  • pain
  • pressure
  • heaviness
  • blurred vision
  • loss of vision (may be temporary or permanent)
  • headache
  • face drooping
  • trouble speaking
  • numbness or weakness on one side of your body
  • loss of balance
  • confusion
  • agitation
  • hallucinations (seeing or hearing things that aren’t real)
  • thoughts of suicide or hurting yourself
  • pain in your abdomen (stomach area)
  • bloody diarrhea
  • nausea and vomiting
  • agitation
  • confusion
  • hallucinations (seeing or hearing things that aren’t real)
  • fast heart rate
  • shaking
  • sweating
  • big pupils (dark centers of your eyes)
  • diarrhea
  • rigid muscles
  • Seizures
  • Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history.

    Cinie oral tablet can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well.

    To help avoid interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking. To find out how this drug might interact with something else you’re taking, talk to your doctor or pharmacist.

    Generic Name: Cinie succinate Dosage Form: tablet

    Medically reviewed by Drugs.com. Last updated on Oct 1, 2018.

    Cinie Succinate Tablets

    How to use Cinie Succinate

    Read the Patient Information Leaflet if available from your pharmacist before you start taking Cinie and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

    Take this medication by mouth with or without food as directed by your doctor, at the first sign of a migraine. The dosage is based on your medical condition and response to treatment. If there is no improvement in your symptoms, do not take more doses of this medication before talking to your doctor. If your symptoms are only partly relieved, or if your headache comes back, you may take another dose at least two hours after the first dose. Do not take more than 200 milligrams in a 24-hour period.

    This medication may also be used as a backup for Cinie injection. If your symptoms are only partly relieved or your headache comes back, you may take a dose of Cinie by mouth at least two hours after the injection, up to a maximum of 100 milligrams in a 24-hour period.

    If you have a higher risk for heart problems (see Precautions), your doctor may perform a heart exam before you start taking Cinie. He/she may also direct you to take your first dose of this medication in the office/clinic to monitor for serious side effects (such as chest pain). Talk to your doctor for details.

    If you are using drugs for migraine attacks on 10 or more days each month, the drugs may actually make your headaches worse (medication overuse headache). Do not use medications more often or for longer than directed. Tell your doctor if you need to use this medication more often, or if the medication is not working as well, or if your headaches get worse.

    Interactions that increase your risk of side effects

    Side effects from Cinie: Taking Cinie with certain medications raises your risk of side effects from Cinie. Examples of these drugs include:

    • Tricyclic antidepressants, such as amitriptyline. You’re at higher risk of developing a serious condition called serotonin syndrome if you take these drugs. Symptoms can include agitation, sweating, fast heartbeat, or hallucinations (seeing or hearing things that aren’t real). They can also include nausea, vomiting, diarrhea, or loss of balance.
    • Selective serotonin reuptake inhibitors used to treat depression, such as sertraline or fluoxetine. You’re at higher risk of developing a serious condition called serotonin syndrome if you take these drugs. Symptoms can include agitation, sweating, fast heartbeat, or hallucinations (seeing or hearing things that aren’t real). They can also include nausea, vomiting, diarrhea, or loss of balance.
    • Serotonin and norepinephrine reuptake inhibitors, such as venlafaxine or duloxetine. You’re at higher risk of developing a serious condition called serotonin syndrome if you take these drugs. Symptoms can include agitation, sweating, fast heartbeat, or hallucinations (seeing or hearing things that aren’t real). They can also include nausea, vomiting, diarrhea, or loss of balance.
    • Medications used to control headache pain, such as dihydroergotamine, codeine, or hydrocodone. Using too many medications to help control your headache symptoms may make your headache worse. Talk with your doctor about which medications to take to help manage your headache symptoms.

    Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.

    Cinie oral tablet comes with several warnings

    PACKAGE LABEL-PRINCIPAL DISPLAY PANEL - 25 mg Bulk Tablet Label

    To be repacked within six months from the date of manufacturing

    BULK SHIPMENT PLEASE HANDLE CAREFULLY

    Cinie Succinate Tablets 25 mg*

    *Each tablet contains: Cinie succinate equivalent to 25 mg of Cinie.

    CAUTION: FOR REPACKAGING ONLY

    Store at 20º to 25ºC (68º to 77ºF); excursions permitted to 15º to 30ºC (59º to 86ºF) .

    Manufactured by: Aurobindo Pharma Limited Hyderabad-500 072, India

    For patients using Cinie nasal solution:

    This medicine comes with patient directions. Read them carefully before using the medicine, and check with your health care professional if you have any questions.

    Tell your doctor if you suffer from epilepsy or other seizure disorder, or coronary artery disease (or risk factors that include diabetes, menopause, smoking, being overweight, having high blood pressure or high cholesterol, having a family history of coronary artery disease, being older than 40 and a man, or being a woman who has had a hysterectomy).

    Cinie can cause serious side effects on the heart, including heart attack or stroke. Tell your doctor if you have any history of heart or circulation problems. You may not be able to use Cinie.

    You should not use Cinie if you have any of the following: heart disease; angina (chest pain); liver disease; blood circulation problems; ischemic bowel disease; history of a heart attack or stroke; high blood pressure; or a headache that is not like other headache you have had.

    Moreover, do not use Cinie if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan®), tranylcypromine (Parnate®), selegiline (Eldepryl®, Emsam®), or phenelzine (Nardil®) in the past 14 days.

    Do not use Cinie within 24 hours after using any of the following medicines: ergot medicine such as methysergide (Sansert®), ergotamine (Ergostat®, Medihaler®, Cafergot®, Ercaf®, Wigraine®), or dihydroergotamine (D.H.E.®, Migranal Nasal Spray®); or almotriptan (Axert®), eletriptan (Relpax®), frovatriptan (Frova®), naratriptan (Amerge®), rizatriptan (Maxalt®, Maxalt-MLT®), or zolmitriptan (Zomig®).

    You may not be able to use Cinie, or you may require a dosage adjustment or special monitoring during treatment, if you have any of the conditions listed above.

    Cinie is in FDA pregnancy category C. This means that this medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Additionally, your name may need to be listed on a Cinie pregnancy registry when you start using this medication.

    Furthermore, Cinie can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

    What should I do if I forget a dose?

    Cinie is not for routine use. Use it only to relieve your migraine headache as soon as symptoms of the migraine appear.

    What side effects can this medication cause?

    What are the side effects of Cinie?

    Side effects are generally transient. Some common side effects of Cinie:

    Rarely, allergic reactions have been reported, usually in individuals who are highly allergic to multiple allergens. Cinie may elevate blood pressure in individuals with or without a history of high blood pressure. Individuals with uncontrolled high blood pressure should not use Cinie.

    Other important, but rare, side effects associated with Cinie include:

    How it works

    Cinie belongs to a class of drugs called serotonin-1 receptor agonists. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.

    A migraine causes the blood vessels in the brain to expand. It also causes a release of chemicals in the brain that can cause inflammation (swelling and irritation). Cinie works by helping to bring your blood vessels back to their normal size. It also helps prevent your body’s release of these chemicals that cause inflammation.

    Cinie oral tablet may cause drowsiness. It may also cause other side effects.

    For patients taking Cinie tablets:

    Cinie tablets are to be swallowed whole with a full glass of water. Do not break, crush, or chew the tablets before swallowing them.

    If you experience any of the following symptoms, call your doctor immediately:

    chest pain (severe) changes in skin color on face convulsions (seizures) fast or irregular breathing puffiness or swelling of eyelids, area around the eyes, face, or lips shortness of breath, troubled breathing or wheezing

    Other side effects than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

    What storage conditions are needed for this medicine?

    Always keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

    Please remember to throw away any medication that is outdated or no longer needed. If necessary, talk to your pharmacist about the proper disposal of your medication.

    In case of an emergency/overdose

    Should an overdose occur whilst taking Cinie, call your local poison control center on 1-800-222-1222. However, if the victim has collapsed or is not breathing, please call the local emergency services immediately on 911.

    Precautions

    Before using Cinie, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

    Before using this medication, tell your doctor or pharmacist your medical history, especially of: blood circulation problems (for example, in your legs, arms/hands, or stomach), certain types of headaches (hemiplegic or basilar migraine), heart problems (such as chest pain, irregular heartbeat, previous heart attack), liver disease, seizure, stroke or "mini-stroke" (transient ischemic attack).

    Certain conditions can increase your risk for heart problems. Tell your doctor if you have any of these conditions, including: high blood pressure, high cholesterol, diabetes, family history of heart disease, overweight, smoker, postmenopausal (women), age more than 40 years (men).

    This drug may make you dizzy or drowsy. Alcohol or marijuana (cannabis) can make you more dizzy or drowsy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis).

    Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

    The risk of heart disease, liver disease, and high blood pressure increases with age. Older adults may be more sensitive to the side effects of this drug, especially increased blood pressure and heart problems.

    During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

    This drug passes into breast milk in small amounts. Consult your doctor before breast-feeding.


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