• Active Ingredient: Aspirin
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What is Aggrenox?

The active ingredient of Aggrenox brand is aspirin. Aspirin is a salicylate (sa-LIS-il-ate). It works by reducing substances in the body that cause pain, fever, and inflammation.

Used for

Aggrenox is used to treat diseases such as: Angina, Angina Pectoris Prophylaxis, Ankylosing Spondylitis, Antiphospholipid Syndrome, Aseptic Necrosis, Back Pain, Fever, Heart Attack, Ischemic Stroke, Ischemic Stroke, Prophylaxis, Juvenile Rheumatoid Arthritis, Kawasaki Disease, Myocardial Infarction, Prophylaxis, Niacin Flush, Osteoarthritis, Pain, Prevention of Thromboembolism in Atrial Fibrillation, Prosthetic Heart Valves - Thrombosis Prophylaxis, Prosthetic Heart Valves, Mechanical Valves - Thrombosis Prophylaxis, Revascularization Procedures, Prophylaxis, Rheumatic Fever, Rheumatoid Arthritis, Sciatica, Spondyloarthritis, Systemic Lupus Erythematosus, Thromboembolic Stroke Prophylaxis, Transient Ischemic Attack.

Side Effect

Possible side effects of Aggrenox include: nervousness; Abdominal or stomach pain, cramping, or burning; muscle tremors; greatly decreased frequency of urination or amount of urine; increased thirst.

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2. "Product Information. Bayer Aggrenox (Aggrenox)." Bayer, West Haven, CT.

3. "Product Information. Durlaza (Aggrenox (acetylsalicylic acid))." New Haven Pharmaceuticals, North Haven, CT.

4. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

Aggrenox and children

Aggrenox is not usually suitable for those aged under 16 years, because it can increase the risk of Reye's syndrome, which can appear after a virus, such as a cold, flu, or chicken pox. It can lead to permanent brain injury or death.

However, a specialist may prescribe Aggrenox for a child under supervision if they have Kawasaki disease, and to prevent blood clots from forming after heart surgery.

Acetaminophen (paracetamol, Tylenol) and ibuprofen are generally used instead.

Q: Could a daily baby Aggrenox increase potassium levels in the blood?

A: According to available drug information, Aggrenox can cause hyperkalemia (increased levels of potassium in the blood). If you are concerned regarding your risk for hyperkalemia associated with Aggrenox treatment, it is important to contact your health care provider. Aggrenox is a salicylate which works by reducing substances in your body that lead to pain, fever or inflammation. Aggrenox is used to treat mild to moderate pain, reduce fever or inflammation and, often times, used to treat or prevent heart attacks, strokes and angina (chest pain). The use of Aggrenox for various cardiovascular conditions should only be under the guidance of your health care provider. A serious side effect associated with Aggrenox is bleeding, so it is important to inform all of your doctors if you take Aggrenox. Less serious side effects that may occur include upset stomach, heartburn, drowsiness and headache. Aggrenox should be taken with a full glass of water and can be taken with food or milk if stomach upset occurs. Enteric-coated Aggrenox is formulated to be easier on the stomach, but also may be taken with food or milk. Do not crush, break or chew enteric-coated Aggrenox. Enteric-coated Aggrenox should be swallowed whole. Do not take Aggrenox if the bottle has a strong vinegar odor, this may indicate that the Aggrenox is no longer effective and should be properly disposed of. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. Beth Isaac, PharmD

Important: Aggrenox may cause allergic reactions; this is more common in people who have asthma. Stop taking Aggrenox and speak with a doctor urgently if you have an allergic reaction or develop any breathing difficulties.

If you experience any other symptoms which you think may be due to the tablets, speak with your doctor or pharmacist for further advice.

Q: Who should avoid taking Aggrenox every day? I am a 58 years old female. I am overweight, have slightly high cholesterol and high blood pressure. I take a multivitamin and omega-3 fish oil capsules.

A: Aggrenox is in a medication class called salicylates. Aggrenox, in prescription form, is used to treat symptoms of osteoarthritis, rheumatoid arthritis, systemic lupus erythematosus, and other conditions associated with pain and swelling. Over-the-counter Aggrenox is used to lessen fever and treat pain from a variety of conditions. In addition, over-the-counter Aggrenox is used to prevent heart attack in people who have had a heart attack or who experience angina (chest pain) and it is also used in the treatment of a heart attack. Over-the-counter Aggrenox is also used to prevent certain types of strokes. Aggrenox works by blocking the production of certain naturally-occurring substances that lead to fever, pain, swelling, and blood clots. Aggrenox can cause serious side effects including bleeding and gastric ulcers. Aggrenox therapy may have benefits, but it is not without risks. Some of the benefits of Aggrenox may include prevention of first and second heart attack, reduction in heart disease risk, and prevention of stroke. Some of the risks involved in Aggrenox therapy include hemorrhagic stroke, gastrointestinal bleeding, allergic reaction, and tinnitus (ringing in the ears). Both the benefits and risks of Aggrenox therapy are patient specific and may depend on certain factors including heart disease risks, family history, age, sex, and other medical conditions. Please consult with your health care provider in regards to Aggrenox therapy. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. Kristen Dore, PharmD

By Lynn Marks | Medically Reviewed by Robert Jasmer, MD

Latest Update: 2015-03-03 Copyright © 2014 Everyday Health Media, LLC

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