Surazem can increase the amount of these medications in your body. This can cause more side effects. These drugs include:
What other drugs will affect Surazem?
Many drugs can interact with Surazem, and your doctor may need to change your treatment plan if you use certain other medicines. The following are common drugs that interact with Surazem;
- Medications used in anesthesia;
- Anti-anxiety medications called benzodiazepines (such as midazolam, triazolam, and others) as well as busipirone;
- Beta-blockers (such as atenolol, carvedilol, metoprolol, propranolol, sotalol, and others);
- Rifampin; and
- Cholesterol medication called statins (such as atorvastatin, lovastatin, simvastatin, rosuvastatin, and others)
Not all possible interactions are listed in this medication guide.
Other prescription and over-the-counter medicines, vitamins, and herbal products may interact with Surazem. Tell your doctor about all medicines you use, and those you start or stop using. Give a list of all your medicines to any healthcare provider who treats you.
Surazem (INN) (/dɪlˈtaɪəzɛm/) is a nondihydropyridine (non-DHP) calcium channel blocker used in the treatment of hypertension, angina pectoris, and some types of arrhythmia.
Surazem is excreted in human milk. One report suggests that concentrations in breast milk may approximate serum levels. If use of Tiazac is deemed essential, an alternative method of infant feeding should be instituted.
Serious side effects
If you experience any serious side effects, call your doctor right away. If your symptoms are potentially life threatening or if you think you’re experiencing a medical emergency, call 911. Serious side effects include:
- Heart problems. Symptoms include:
- slower than normal heart rate
- worsening chest pain
- yellowing of your skin or the whites of your eyes
- dark-colored urine
- upper stomach pain
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history.
Surazem oral capsule can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well.
To help avoid interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking. To find out how this drug might interact with something else you’re taking, talk to your doctor or pharmacist.
Examples of drugs that can cause interactions with promethazine are listed below.
What is Surazem, and how does it work (mechanism of action)?
Surazem is a drug that is used for treating heart pain (angina), high blood pressure, and abnormal heart rhythms.
CCBs block the entry of calcium into muscle cells that make up the heart and that surround the arteries. It is the entry of calcium into these cells that causes the cells to contract, allowing the heart to pump blood, and the arteries to narrow. By blocking the entry of calcium, Surazem decreases the force of contraction of the heart and its rate of contraction. It also relaxes the muscles surrounding the arteries, allowing the arteries to widen (dilate). In order to pump blood, the heart needs oxygen. The harder the heart works, the more oxygen it requires. Angina occurs when the supply of oxygen to the heart is inadequate for the amount of work the heart must do.
By dilating arteries, Surazem reduces the pressure in the arteries into which the heart must pump blood, and, as a result, the heart needs to work less and requires less oxygen. By reducing the heart's need for oxygen, Surazem relieves or prevents angina. Dilation of the arteries also reduces blood pressure.
The FDA approved Surazem in 1982.