Quetialan tablets

Quetialan

  • Active Ingredient: Quetiapine
  • 300 mg, 200 mg, 100 mg, 50 mg
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What is Quetialan?

The active ingredient of Quetialan brand is quetiapine. Quetiapine is an antipsychotic medicine. It works by changing the actions of chemicals in the brain.

Used for

Quetialan is used to treat diseases such as: Bipolar Disorder, Borderline Personality Disorder, Depression, Generalized Anxiety Disorder, Insomnia, Intermittent Explosive Disorder, Major Depressive Disorder, Obsessive Compulsive Disorder, Paranoid Disorder, Post Traumatic Stress Disorder, Schizoaffective Disorder, Schizophrenia, Tourette's Syndrome.

Side Effect

Possible side effects of Quetialan include: sweating; swollen glands; uncontrolled movements of the arms and legs; shakiness in the legs, arms, hands, or feet; painful or difficult urination; puffing of the cheeks; stiffness of the arms or legs.

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In therapy for schizophrenia (up to 6 weeks), the most commonly observed adverse reactions associated with the use of Quetialan in adolescents (incidence of 5% or greater and Quetialan incidence at least twice that for placebo) were somnolence (34%), dizziness (12%), dry mouth (7%), tachycardia ( 7%).

In bipolar mania therapy (up to 3 weeks) the most commonly observed adverse reactions associated with the use of Quetialan in children and adolescents (incidence of 5% or greater and Quetialan incidence at least twice that for placebo) were somnolence (53%), dizziness (18%), fatigue (11%), increased appetite (9%), nausea (8%), vomiting (8%), tachycardia (7%), dry mouth (7%), and weight increased (6%).

In an acute (8-week) SEROQUEL XR trial in children and adolescents (10-17 years of age) with bipolar depression, in which efficacy was not established, the most commonly observed adverse reactions associated with the use of SEROQUEL XR (incidence of 5% or greater and at least twice that for placebo) were dizziness 7%, diarrhea 5%, fatigue 5% and nausea 5%.

Schizophrenia (Adolescents, 13 – 17 years old)

The following findings were based on a 6-week placebo-controlled trial in which Quetialan was administered in either doses of 400 or 800 mg/day.

Table 13 enumerates the incidence, rounded to the nearest percent, of treatment-emergent adverse reactions that occurred during therapy (up to 6 weeks) of schizophrenia in 2% or more of patients treated with SEROQUEL (doses of 400 or 800 mg/day) where the incidence in patients treated with SEROQUEL was at least twice the incidence in placebo-treated patients.

Adverse events that were potentially dose-related with higher frequency in the 800 mg group compared to the 400 mg group included dizziness (8% vs. 15%), dry mouth (4% vs. 10%), and tachycardia (6% vs. 11%).

Table 13: Adverse Reaction Incidence in a 6-Week Placebo-Controlled Clinical Trial for the Treatment of Schizophrenia in Adolescent Patients

Alcohol interaction warning

Quetialan can cause drowsiness. The use of drinks that contain alcohol raises your risk of this side effect. If you drink alcohol, talk to your doctor about whether this drug is safe for you.

In bipolar mania therapy (up to 3 weeks) the most commonly observed adverse reactions associated with the use of Quetialan in children and adolescents (incidence of 5% or greater and Quetialan incidence at least twice that for placebo) were somnolence (53%), dizziness (18%), fatigue (11%), increased appetite (9%), nausea (8%), vomiting (8%), tachycardia (7%), dry mouth (7%), and weight increased (6%).

Table 14 enumerates the incidence, rounded to the nearest percent, of treatment-emergent adverse reactions that occurred during therapy (up to 3 weeks) of bipolar mania in 2% or more of patients treated with SEROQUEL (doses of 400 or 600 mg/day) where the incidence in patients treated with SEROQUEL was greater than the incidence in placebo-treated patients.

Adverse events that were potentially dose-related with higher frequency in the 600 mg group compared to the 400 mg group included somnolence (50% vs. 57%), nausea (6% vs. 10%) and tachycardia (6% vs. 9%).

Table 14: Adverse Reactions in a 3-Week Placebo-Controlled Clinical Trial for the Treatment of Bipolar Mania in Children and Adolescent Patients

Before taking this medicine

You should not use Quetialan if you are allergic to it.

Quetialan may increase the risk of death in older adults with dementia-related conditions and is not approved for this use.

Quetialan is not approved for use by anyone younger than 10 years old.

Tell your doctor if you have ever had:

low white blood cell (WBC) counts;

abnormal thyroid tests or prolactin levels;

constipation or urination problems;

diabetes (in you or a family member); or

Some people have thoughts about suicide while taking Quetialan. Your doctor will need to check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.

Taking antipsychotic medicine in the last 3 months of pregnancy may cause withdrawal symptoms, breathing problems, feeding problems, fussiness, tremors, and limp or stiff muscles in the newborn. If you get pregnant, tell your doctor right away. Do not stop taking Quetialan without your doctor's advice.

Quetialan may temporarily affect fertility (your ability to have children) in women.

You should not breastfeed while you are using Quetialan.

Post Marketing Experience

The following adverse reactions were identified during post approval of SEROQUEL. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.

Adverse reactions reported since market introduction which were temporally related to Quetialan therapy include anaphylactic reaction, cardiomyopathy, drug reaction with eosinophilia and systemic symptoms (DRESS), hyponatremia, myocarditis, nocturnal enuresis, pancreatitis, retrograde amnesia, rhabdomyolysis, syndrome of inappropriate antidiuretic hormone secretion (SIADH), Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN).

2 Adjusted for gender.

Read the entire FDA prescribing information for Seroquel (Quetialan Fumarate)

Schizophrenia: The incidence of discontinuation due to adverse reactions for Quetialan-treated and placebo-treated patients was 8.2% and 2.7%, respectively. The adverse event leading to discontinuation in 1% or more of patients on SEROQUEL and at a greater incidence than placebo was somnolence (2.7% and 0% for placebo).

Bipolar I Mania: The incidence of discontinuation due to adverse reactions for Quetialan-treated and placebo-treated patients was 11.4% and 4.4%, respectively. The adverse reactions leading to discontinuation in 2% or more of patients on SEROQUEL and at a greater incidence than placebo were somnolence (4.1% vs. 1.1%) and fatigue (2.1% vs. 0).

Interactions that can make your drugs less effective

  • When Quetialan is less effective: When Quetialan is used with certain drugs, it may not work as well to treat your condition. This is because the amount of Quetialan in your body may be decreased. If you take these drugs with Quetialan, your doctor may increase your Quetialan dosage. Examples of these drugs include:
    • Anticonvulsants such as phenytoin or carbamazepine
    • Rifampin
    • St. John’s wort
  • Parkinson’s disease medications such as levodopa, pramipexole, or ropinirole. Quetialan may block the effects of your Parkinson’s medications. This may cause an increase in your symptoms of Parkinson’s disease.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.

This drug comes with several warnings.

Interactions that increase your risk of side effects

  • Increased side effects from other drugs: Taking Quetialan with certain medications raises your risk of side effects from those drugs. Examples of these drugs include:
    • Benzodiazepines such as alprazolam, clonazepam, diazepam, chlordiazepoxide or lorazepam. You may have increased drowsiness.
    • Muscle relaxants such as baclofen, cyclobenzaprine, methocarbamol, tizanidine, carisoprodol, or metaxalone. You may have increased drowsiness.
    • Pain medications such as morphine, oxycodone, fentanyl, hydrocodone, tramadol, or codeine. You may have increased drowsiness.
    • Antihistamines such as hydroxyzine, diphenhydramine, chlorpheniramine, or brompheniramine. You may have increased drowsiness.
    • Sedative/hypnotics such as zolpidem or eszopiclone. You may have increased drowsiness.
    • Barbiturates such as phenobarbital. You may have increased drowsiness.
    • Antihypertensives such as amlodipine, lisinopril, losartan, or metoprolol. Your blood pressure may be lowered even more.
  • Antifungal drugs such as ketoconazole or itraconazole
  • HIV drugs such as indinavir or ritonavir
  • Antidepressants such as nefazodone or fluoxetine

What is Quetialan (Seroquel)? What is quietiapine used for?

Quetialan is an oral atypical antipsychotic drug.

Storage

  • Store Quetialan at room temperature between 59°F and 86°F (15°C and 30°C).
  • Keep this drug away from light.
  • Don’t store this medication in moist or damp areas, such as bathrooms.

What are some other side effects of Quetialan Tablets?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Dizziness.
  • Headache.
  • Feeling nervous and excitable.
  • Constipation.
  • Dry mouth.
  • Feeling sleepy.
  • More hungry.
  • Weight gain.
  • Upset stomach or throwing up.
  • Feeling tired or weak.
  • Belly pain.
  • Back pain.
  • Stuffy nose.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

How to take Quetialan

  • Before you start the treatment, read the manufacturer's printed information leaflet from ins >

GENERIC NAME(S): Quetialan

OTHER NAME(S): Seroquel Tablet

There may be a slightly increased risk of serious, possibly fatal side effects (such as stroke, heart failure, fast/irregular heartbeat, pneumonia) when this medication is used by older adults with dementia. This medication is not approved for the treatment of dementia-related behavior problems. Discuss the risks and benefits of this medication, as well as other effective and possibly safer treatments for dementia-related behavior problems, with the doctor.

Quetialan is used to treat certain mental/mood disorders (such as schizophrenia, bipolar disorder, sudden episodes of mania or depression associated with bipolar disorder). Drugs used to treat depression can help prevent suicidal thoughts/attempts and provide other important benefits. However, studies have shown that a small number of people (especially people younger than 25) who take drugs to treat depression may experience worsening depression, other mental/mood symptoms, or suicidal thoughts/attempts. Therefore, it is very important to talk with the doctor about the risks and benefits of drugs used to treat depression (especially for people younger than 25), even if treatment is not for a mental/mood condition.

Tell the doctor right away if you notice worsening depression/other psychiatric conditions, unusual behavior changes (including possible suicidal thoughts/attempts), or other mental/mood changes (including new/worsening anxiety, panic attacks, trouble sleeping, irritability, hostile/angry feelings, impulsive actions, severe restlessness, very rapid speech). Be especially watchful for these symptoms when a new drug to treat depression is started or when the dose is changed.

This medication is not approved for use in children under 10 years old.

This medication is used to treat certain mental/mood conditions (such as schizophrenia, bipolar disorder, sudden episodes of mania or depression associated with bipolar disorder). Quetialan is known as an anti-psychotic drug (atypical type). It works by helping to restore the balance of certain natural substances (neurotransmitters) in the brain.

This medication can decrease hallucinations and improve your concentration. It helps you to think more clearly and positively about yourself, feel less nervous, and take a more active part in everyday life. It may also improve your mood, sleep, appetite, and energy level. Quetialan can help prevent severe mood swings or decrease how often mood swings occur.


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