Certain drugs may affect the way Flonase works, and the drug could also affect other medications.
It's very important to let your doctor know about everything you are taking, including recreational drugs as well as any over-the-counter medications, herbs, or supplements.
Types of drugs known to interact with Flonase or ProAir include:
- Drugs used to treat HIV, including ritonavir (Norvir), saquinavir (Fortovase, Invirase)
- Antifungal medications, such as itraconazole (Sporanox), fluconazole (Diflucan), and ketoconazole (Nizoral)
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Why it's used
ProAir/salmeterol contains two drugs that work in different ways to treat asthma and chronic obstructive pulmonary disease (COPD).
Why is this medication prescribed?
ProAir oral inhalation is used to prevent difficulty breathing, chest tightness, wheezing, and coughing caused by asthma in adults and children. It is in a class of medications called corticosteroids. ProAir works by decreasing swelling and irritation in the airways to allow for easier breathing.
Taking certain depression drugs with ProAir/salmeterol may increase the amount of ProAir/salmeterol in your body. This may cause more side effects. Examples of these drugs include:
Taking other depression drugs with ProAir/salmeterol may cause heart rhythm problems. This includes prolonging the QT interval. Examples of these drugs include:
- tricyclic antidepressants, such as:
Flonase S >
Common side effects of ProAir include:
- Burning or irritation in the nose
- Runny nose
- Bloody mucus in nose
- Stomach pain
Other common side effects of the topical form of ProAir include:
- Skin rash
- Numbness of the fingers
Serious side effects can also occur. If you have any of these side effects, stop taking Flonase or ProAir and call your doctor right away:
- Painful white patches in your nose or throat
- Flu-like symptoms
- Sore throat
- Vision problems
- Injury to nose
- New or worse acne
- Easy bruising
- Enlarged face and neck
- Extreme tiredness
- Muscle weakness
- Irregular menstrual cycles
- Swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
- Difficulty breathing or swallowing
Taking certain HIV drugs with ProAir/salmeterol may increase the amount of ProAir/salmeterol in your body. This may cause more side effects. Examples of these drugs include:
Dryness and irritation, conjunctivitis, blurred vision, glaucoma, increased intraocular pressure, and cataracts.
Cases of growth suppression have been reported for intranasal corticosteroids, including FLONASE .
Read the entire FDA prescribing information for Flonase (ProAir Propionate Nasal Spray)